Browsing Human- und Zahnmedizin by Referee "Neeße, Albrecht Prof. Dr. Dr."
Now showing items 1-11 of 11
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Protektive Effekte körperlicher Aktivität auf die Entwicklung der Nierenfibrose bei chronischer Niereninsuffizienz
(2024-12-20)The rising prevalence of chronic kidney disease (CKD) with its limited therapeutic options still poses a relevant clinical dilemma. Especially therapies that ameliorate the histopathological correlate, i.e. renal fibrosis, ... -
Evaluation der diagnostischen Genauigkeit der B-Bild Sonographie zur Graduierung der Lebersteatose bei Patienten mit chronischer Lebererkrankung
(2024-10-30)AbstractFatty liver disease is characterised by excessive storage of fat. The prevalence in Germany is about 30%. The worldwide prevalence is approximately 25%. This means that about 1.8 billion people are ...
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Pankreatisch zystische Neoplasien und das orointestinale Mikrobiom: Evaluierung als Biomarker
(2024-09-24)Pancreatic cystic neoplasms (PCN) are mostly benign cystic lesions of the pancreas, which can be a precursor lesion for pancreatic cancer. The risk of malignancy varies widely, depending on the entity of the PCN. Despite ... -
Einfluss von SPARC auf den Schweregrad der akuten Pankreatitis in einem genetischen Mausmodell
(2024-06-21)Acute pancreatitis (AP) is a common but severe inflammatory disease that develops upon unspecific acinar cell damage which, via intraparenchymal activation of digestive enzymes, can result in multi organ failure and death. ... -
Untersuchung der pharmakologischen Modulation von ARNT-Homodimeren auf die Renoprotektion
(2023-10-02)Chronic kidney disease is marked by progressive fibrosis and consecutive loss of function – the availability of specific therapies is limited. The bHLH-PAS transcription factor ARNT is able to form homodimeric complexes ... -
Expression of gemcitabine metabolizing enzymes in different pancreatic cancer model systems
(2023-03-23)Pancreatic cancer still exhibits a dismal five-year overall survival rate of 9 % and is foreseen to even increase in incidence and mortality rates in the future. This is due to unspecific symptoms leading to late diagnosis, ... -
In-vitro- und In-vivo-Untersuchungen zum Gemcitabinmetabolismus von Makrophagen im Duktalen Adenokarzinom des Pankreas
(2022-09-26)Despite great scientific and clinical efforts, pancreatic cancer still has a fatal prognosis. In addition to the usually late diagnosis, this is mainly due to the tumour's resistance to chemotherapy. Gemcitabine and ... -
Malnutrition und Outcome bei älteren Patienten (≥ 65 Jahre) mit aggressiven Non-Hodgkin-Lymphomen
(2021-06-08)Both malnutrition and serum albumin (SA) have been shown to be independent negative predictors of impaired treatment response in many hematological malignancies. The body mass index (BMI) as an easily measurable value is ... -
Präklinische Analyse von epithelialen und stromalen Markern in einem transgenen Mausmodell für Pankreaskarzinome
(2021-01-12)Pancreatic ductal adenocarcinoma is amongst the most aggressive cancers and is associated with an extremely poor prognosis. From a histological perspective, pancreatic cancer is char-acterised by a distinct, widespread ... -
Klinische Bedeutung des abführenden Schenkels im Vergleich zur Rektoskopie in der Diagnostik vor Ileostomarückverlagerung
(2020-07-23)In the context of visceral resections, the creation of an artificial bowel outlet (stoma) may be necessary. Among other aspects, the protective double loop ileostomy has become established. One lumen, which conveys the ... -
Messung der Lebersteifigkeit mittels der 2D-Scherwellen-Elastographie mit dem Sonographiegerät LOGIQ E9 (Firma GE Healthcare) bei gesunden Probanden, Leber-gesunden Patienten sowie Patienten mit Leberzirrhose zur Generierung von Normwerten
(2020-06-11)This work aims at generating standard values for liver stiffness of liver-healthy people for the sonography device LOGIQ E9 (GE Healthcare), which is used in the clinic for Gastroenterology, gastrointestinal Oncology, and ...