Dokumente Human- und Zahnmedizin nach Gutachter "Tönges, Lars Prof. Dr."
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Differenzierung der Pharmakotherapie mit Fasudil und Riluzol im SOD1-G93A Mausmodell der Amyotrophen Lateralsklerose
(2018-12-04)Although there was progress in understanding the aetiopathogenesis of ALS in recent years, clinical researchers still have only one established pharmaceutical for treatment of ALS in human which is Riluzole and prolongs ... -
Effekte der präsymptomatischen Applikation der Rho-Kinase-Inhibitoren Fasudil und Y-27632 im SOD1-(G93A)-Mausmodell der Amyotrophen Lateralsklerose
(2017-02-20)This study demonstrates the successful pre-clinical testing of a new pharmacological approach in the treatment of amyotrophic lateral sclerosis using Rho-kinase-(ROCK)-inhibition. The Rho/ROCK signal cascade represents an ...