Human- und Zahnmedizin: Recent submissions
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Einfluss der klinischen und interventionellen Parameter im Rahmen der mpMRT/TRUS Fusionsbiopsie der Prostata auf die Detektionsrate des Prostatakarzinoms
(2024-03-01)Prostate cancer is one of the most common cancers in men worldwide. In this context, this study investigates clinical and interventional parameters that may influence the detection rate of prostate cancer in the context ... -
Kardiovaskuläre Einflussfaktoren auf die gesundheitsbezogene Lebensqualität von onkologischen Patienten
(2024-02-29)Aims Five percent of the German population is living with the diagnosis of a malignant disease, which transforms – due to higher survival rates – to a chronic disease. Maintaining quality of life (QoL) has become increasingly ... -
Evaluation des Göttinger Kooperationsprojekts FIDEM (Frühe Informationen und Hilfen bei Demenz): Projekt-Etablierung und Erfahrungen von ärztlichen sowie nicht-ärztlichen Beteiligten
(2024-02-21)Early information and support in dementia (FIDEM) is a cooperation model that focuses on networking between general practitioners and non-medical cooperation partners (e.g. occupational therapists, care counselling, other ... -
Weitwinkel-Angiographie-Bildgebung zur Detektion von Ischämien bei Retinalen Venenverschlüssen
(2024-02-21)Retinal vein occlusions (RVO) are a relatively common and clinically relevant ophthalmological condition with numerous potential complications. Since diagnosis using fluorescein angiography (FAG) imaging, particularly the ... -
Einfluss der Zeit zwischen Diagnose und Therapie des Prostatakarzinoms mittels radikaler Prostatektomie auf klinische und onkologische Parameter
(2024-02-16)Prostate cancer is currently the most common cancer diagnosis among men in Germany and ranks among the top fatal diseases. Particularly in times of pandemic, the influence of the time interval between histological confirmation ... -
Short- and long-term quality of life in patients after surgically treated Spondylodiscitis
(2024-02-13)Background Spondylodiscitis affects a fragile patient population frequently fraught with severe comorbidities. Data on long-term outcomes, especially for patients undergoing surgery, are scarce. The aim of this study was ... -
Auswirkungen einer Variation im TREM-1-Gen auf die Mortalität bei septischen Patienten
(2024-02-12)Sepsis is a life-threatening organ dysfunction caused by a disturbed immune response of the organism to an infectious agent. Sepsis is one of the most common causes of death in intensive care units. Due to its epidemiology ... -
Chirurgische Behandlung der isolierten Aortenisthmusstenose: Risiken und Komplikationen im Langzeitverlauf
(2024-02-09)Aortic coarctation is the fifth most common congenital heart defect in Germany. Pathophysiologically, it is a narrowing at the distal end of the aortic arch, which results in reduced perfusion in the lower half of the body. ... -
MET-Alterationen als therapeutisches Target bei metastasierten kolorektalen Karzinomen
(2024-02-09)Introduction: An enhanced understanding of the molecular pathways driving oncogenesis has yielded an increasing number of potential therapeutic targets. MET amplification has been shown to be involved in angiogenesis, ... -
Match-paired study to assess influence of Kinematic versus Mechanical Alignment in Total Knee Replacement
(2024-02-09)Introduction: Match-paired study compares the early clinical and radiological outcomes after 6 weeks and 1-year between kinematic alignment total knee arthroplasty (KA TKA) and mechanical alignment total knee arthroplasty ... -
Charakterisierung von BCAS1-positiven Oligodendrozyten während der menschlichen Gehirnentwicklung
(2024-02-05)This work investigated the comparison between different stages of pre- and early postnatal development of oligodendrocytes in the white matter of the central nervous system. The main focus was to aim at BCAS1+ oligodendrocytes ... -
Standardisierte Zeitintervalle im Management von Patienten mit akutem ischämischen Schlaganfall: prognostische und prädiktive Bedeutung
(2024-02-05)Background: The importance of efficient stroke time management on the clinical outcome of thrombectomized patients has been demonstrated by numerous controlled randomized trials (RCT). Although time is an important predictor ... -
Effekte der transkutanen Vagusnervstimulation auf kardiovaskuläre und autonome Parameter
(2024-02-05)Background: Different diseases, including cardiovascular and inflammatory diseases, are associated with a shift in sympathovagal balance in the sympathetic direction. Invasive vagus nerve stimulation is a treatment method ... -
Langzeit-EIT-Monitoring als Indikator für die Entstehung eines Lungenödems während maschineller Beatmung im Tierexperiment
(2024-02-02)In the present study, the question of the extent to which long-term EIT monitoring (EIT = electrical impedance tomography) is suitable as an indicator for the development of pulmonary oedema during mechanical VILI ventilation ... -
Detektion diagnostischer Frühmarker der Nierenfibrose im Urin von Patienten mit Alport-Syndrom mittels proteomischer Methoden
(2024-02-02)Detection of early diagnostic tools of kidney sclerosis in the urine of patients with Alport-Syndrome using proteomic methods. -
Einfluss von Bluttransfusionen auf das Outcome von Patienten mit Sepsis
(2024-01-29)Despite modern medical care, sepsis remains an issue, especially for the aging society with an increasing number of multimorbid patients. The group of sepsis patients shows large heterogeneity and there are numerous factors ... -
Kalziumhandling und Kalziumpufferung bei familiärer dilatativer Kardiomyopathie am Modell der induzierten pluripotenten Stammzellen
(2024-01-29)Dilated cardiomyopathy (DCM) is a heterogeneous disease characterised by left ventricular dilatation and a reduced ejection fraction. In addition to progressive left heart failure, the poor clinical prognosis is primarily ... -
PFKFB3-Inhibition während einer Radiochemotherapie des Rektumkarzinoms – Überprüfung in einem patient-derived xenograft In-vivo-Modell
(2024-01-29)Colorectal cancer (CRC) is the third most common cancer diagnosed worldwide and the second leading cause of cancer death. Approximately 30% of colorectal carcinomas are localized in the rectum. Neoadjuvant radiotherapy ... -
Digitalisierung der Klinik für Unfallchirurgie, Orthopädie und plastische Chirurgie
(2024-01-26)Clinical relevanceThe increasing digitalization is a process that can be observed worldwide and extends over many different areas. In the healthcare sector, too, innovations are researched, developed and tested that ...
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Ablationsbehandlung epikardialer akzessorischer Leitungsbahnen über das Koronarvenensystem bei Kindern und Jugendlichen
(2024-01-24)This retrospective data analysis was used to collect data from 24 patients ≤ 18 years who underwent ablation treatment of accessory pathways within the coronary venous system in Göttingen between October 2002 and December ...