Human- und Zahnmedizin: Recent submissions
Now showing items 21-40 of 3258
-
Eine randomisierte prospektive Kohortenstudie: Präventiver Effekt verschiedener Hangboardtrainingsmethoden zur Stärkung des muskuloskelettalen Systems der Hand
(2025-06-04)Improving climbing performance strongly depends upon effective training methods. Hangboard training is one of the most popular approaches to increase finger and forearm strength. Training protocols are based on maximizing ... -
Einstellungen von Patientenorganisationen zu personalisierter Medizin und Big Data – Eine empirisch-ethische qualitative Studie
(2025-06-03)Background: Within only a few decades, ongoing developments and innovations in digitalization processes have led to a rapid accumulation of extensive data sets across various fields and contexts, including medical and ... -
Künstliche Intelligenz in der Röntgen-Thorax-Analyse auf einer Intensivstation: Eine retrospektive Studie
(2025-05-28)Supine chest radiographs are among the most frequently performed imaging studies in intensive care units. This study investigates the effect of an artificial intelligence (AI)-based system on the diagnostic performance and ... -
Die prädiktive Aussagekraft von BNP und NT-pro BNP für Vorhofflimmern bei Patienten über 75 Jahren in der Primärversorgung (Daten der SCREEN-AF Studie)
(2025-05-27)Atrial fibrillation (AF) is a common supraventricular arrhythmia that predominantly affects older adults, constituting a significant risk factor for ischemic stroke. Its frequent asymptomatic and paroxysmal presentation ... -
Die COVID-19-Pandemie als Prüfstein für gerechte Ressourcenverteilung im Krankenhaus
(2025-05-27)This dissertation examines the issue of equitable resource allocation in five hospitals during the initial phase of the COVID-19 pandemic, using qualitative expert interviews. The study responds to ethical and organizational ... -
SHISA3, a novel Wnt-dependent Signature in the Developing and Failing Heart
(2025-05-27)Understanding how vascular cells develop can be used to discover new paths of cell renewal within the diseased heart, with a particular focus on the epicardium for cardiac regeneration. Previous studies have shown that ... -
Living cell super resolution microscopy of intact cardiac nanodomains in a GFP-reporter-mouse-model
(2025-05-26)The aim of this thesis is to validate the first application of RESOLFT imaging in a transgenic mouse model in order to confirm a novel transgenic-microscopic approach and from there on address relevant questions in cardiac ... -
2D-Shear-wave Elastographie zur Evaluation der Lebersteifigkeit bei systemischer Sklerodermie und primärer biliärer Cholangitis
(2025-05-26)2D Shear-wave elastography (2D-SWE) is a simple, proven, and inexpensive method for determining the liver stiffness (LS). In the present study, we examined the LS using 2D-SWE in patients with systemic sclerosis (SSc) and ... -
Routineimpfungen im Kindesalter und ihre Assoziation mit perinataler Betreuung
(2025-05-26)Incomplete or missing doses in routine childhood immunizations remain a significant public health concern. Health systems in low- and middle-income countries (LMICs) often face challenges in ensuring full vaccination ... -
Assessment and Advancement of Genotype Imputation for genome-wide Association Studies
(2025-05-20)In genome-wide association studies (GWASs), genetic markers are independently tested across the whole genome to find genetic variants associated with a phenotype for a given population. The most commonly used markers for ... -
Verlauf der Knochendichte und der Knochenumbaumarker unter der Therapie mit Romosozumab
(2025-05-20)As a result of demographic changes and the associated increase in life expectancy, pharmacological treatment of osteoporosis will continue to gain importance in the coming years. Currently, the monoclonal antibody romosozumab ... -
Untersuchung von Translationalem Readthrough bei Peroxisomalen Biogenesestörungen im Zellmodell
(2025-05-19)Premature termination codon (PTC) mutations account for approximately 10% of pathogenic variants in monogenic diseases. Stimulation of translational readthrough, also known as stop codon suppression, using translational ... -
Etablierung eines Zellkulturmodells zur Erforschung zyklischer Druckschwankungen an retinalen Ganglienzellen
(2025-05-19)Glaucoma, one of the most common causes of irreversible vision loss, leads to the progressive degeneration of retinal ganglion cells (RGCs), with elevated intraocular pressure being the only modifiable risk factor. However, ... -
Proteomische Analyse von nicht-kleinzelligen Lungenkarzinomen
(2025-05-19)Non-small cell lung cancer is a very common disease worldwide with a poor prognosis. Lung cancer is responsible for approximately 1.6 million deaths worldwide each year. A paradigm shift in the treatment of affected patients ... -
Einfluss der differenzierten Präsentation multipler Wachstumsfaktoren in biomimetischen Multilayerbeschichtungen von Titanimplantaten auf die Angiogenese und Osteogenese
(2025-05-16)The aim of the present study was to test the simultaneous and sequential release of the growth factors rhVEGF165 and rhBMP2 from poly-L-lysine-heparin (PLL-Hep) and poly-L-lysine-heparin-collagen (PLL-Hep-Col) poly-electrolyte ... -
Einfluss von Citalopram auf die Alzheimer-Pathologie im Tg4-42-Mausmodell
(2025-05-12)Alzheimer’s disease is the most common form of dementia and currently remains without a curative or preventive treatment. Characteristic pathological features include amyloid-β (Aβ-) accumulation, neuroinflammation, synaptic ... -
Tau-Protein im Liquor cerebrospinalis in der Differenzialdiagnostik bei Morbus Alzheimer und sporadischer Creutzfeldt- Jakob-Krankheit
(2025-05-12)In der Diagnostik der Alzheimer-Demenz (AD) hat sich das totale Tau (t-Tau) im Liquor als ein wichtiges diagnostisches Mittel etabliert. Allerdings wurden auch bei Patient*innen mit Creutzfeldt-Jakob-Krankheit (CJK) stark ... -
Detektion von Nebenbefunden bei röntgenologischer Bildgebung in der kieferorthopädischen Praxis: eine fragebogenbasierte Untersuchung
(2025-05-09)Background: In orthodontic practice, radiographs with large fields of view - such as orthopantomogram (OPT) and lateral cephalogram (LC) radiographs - are routinely acquired and assessed. The reliability of identifying ... -
Cross-National Analysis of IVF Registry Data
(2025-05-08)Approximately 15% (1 in 6) of couples worldwide face infertility issues, and assisted reproductive technology (ART), which is now adopted globally, has become a key method to address these challenges. Various in-vitro ... -
Der Effekt von Erythropoetin auf das Überleben von Gehirnnervenzellen der Locusta migratoria nach Schädigung durch UV-Strahlung
(2025-05-08)Erythropoietin (Epo) is a well-known candidate for neuroprotection due to its anti-apoptotic properties. One limiting factor in previous studies has been thromboembolic side effects. Various receptors and signaling pathways ...