Human- und Zahnmedizin
Recent Submissions
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Evaluation der nicht-invasiven Leberelastizitäsmessung mittels 2D-Scherwellen-Elastographie (LOGIQ E9 shear wave elastography) im Verlauf der Gewichtsreduktion bei Adipositas im Rahmen des Therapiekonzeptes OPTIFAST®-52
(2025-04-24)Due to its high prevalence and potentially asymptomatic course, non-alcoholic fatty liver disease (NAFLD) remains a challenge in medicine. NAFLD may progress to non-alcoholic steatohepatitis (NASH) and eventually lead to ... -
Verschlussrate sowie intra- und postoperative Komplikationen nach Makulalochchirurgie
(2025-04-23)The full thickness macular hole is a vision threatening condition and without treatment the risk of permanent and severe vision loss is high. Currently, the only established and standard treatment for full thickness macular ... -
Endoplasmatischer Retikulum-Stress im Zellkulturmodel für chronische Muskelentzündungen
(2025-04-23)Background: Inclusion body myositis (IBM) is an acquired myopathy in individuals over the age of fifty. It is characterized by progressive muscle atrophy and weakness that leads to severe disability. Currently there is no ... -
Longitudinal Structural Voxel based Morphometry of 1.5 tesla MRI in early Parkinson’s disease
(2025-04-23)Parkinson’s disease is a multisystemic, progressive neurodegenerative disorder characterized by the gradual loss of dopaminergic neurons in the substantia nigra, resulting in a wide range of motor and non-motor symptoms ... -
Morphologische und mechanistische Analyse des Wachstums retinaler Ganglienzellen unter Einfluss von Mikrofluidik in vitro
(2025-04-22)Replacing retinal ganglion cells (RGCs) in a degenerated optic nerve is not yet possible but may become feasible in the future through stem cell transplantation. Microfluidic fluid streams, presumably present in the optic ... -
Differentialdiagnostische Abgrenzung des Panayiotopoulos-Syndroms von der Migräne
(2025-04-22)Migraine is among the most common primary headache syndromes in childhood and adolescence. Panayiotopoulos syndrome (PS) (also known as early-onset benign occipital seizure susceptibility syndrome (EBOSS) or self-limited ... -
Prognostische Bedeutung von hochsensitivem Troponin I bei normotensiven Patienten mit akuter Lungenembolie
(2025-04-17)This study investigated the prognostic significance of high-sensitivity troponin I (hsTnI) in normotensive patients with acute pulmonary embolism (PE). The goal was to identify an optimized cutoff value for hsTnI for risk ... -
Einfluss von Elektrolytkonzentrationen auf Qualitätsparameter bei Elektrokonvulsionstherapie
(2025-04-14)The effectiveness of electroconvulsive therapy depends on achieving a generalized seizure. Several strategies exist on how to improve seizure quality. From clinical observations we know that electrolyte disturbances often ... -
Evaluation der Behandlung mit KAN0438757 in Kombination mit verschiedenen Chemotherapien im glykolytischen und lipogenen Subtyp des duktalen Pankreaskarzinoms
(2025-04-14)Despite current treatment options, the 5-year survival rate for patients with pancreatic ductal adenocarcinoma is below 10%. This highlights the relevance of new therapeutic approaches. Pancreatic ductal adenocarcinoma, ... -
Zur Bedeutung von Typ-D-Persönlichkeit und Bindungsstil bei Patient*innen mit kardiovaskulären Risikofaktoren oder Herzinsuffizienz aus der Diast-CHF-Studie
(2025-04-14)OBJECTIVE: Although the prevalence of depression, anxiety and vital exhaustion in cardiac patients is high and can contribute to the deterioration of their health, mental disorders are often underdiagnosed and inadequately ... -
In-vivo-Diagnostik und Therapiemonitoring mittels 18F-FDG-Positronenemissionstomographie im Tg4-42 Alzheimer-Mausmodell
(2025-04-14)In this study, two groups of Alzheimer's model mice of the Tg4-42 type were injected intravenously with 18F-FDG at the age of 7 months and 3 months. Subsequently, the 18F-FDG uptake of the brain was visualized by PET/MRI. ... -
Der Einfluss von 8-Prenylnaringenin und Alendronat in Kombination mit vertikaler Ganzkörpervibration auf den Wirbelkörper des osteopenischen Rattenmodells
(2025-04-14)Osteoporosis is a systemic disease of the skeleton with reduced bone stability and increased fracture risk. Due to rising osteoporosis-related healthcare costs, the disease and its treatment represent an increasing health ... -
Gesundheitsbezogene Lebensqualität von Kindern nach Schädel-Hirn-Trauma: Vergleich der Kinder- und Elternperspektive
(2025-04-14)Pediatric Health-Related Quality of Life (HRQoL) as a measure of subjective well-being and functional capacity has gained increasing importance in recent years. However, the HRQoL of children and adolescents following a ... -
Charakterisierung der LIFR/STAT3-Inhibition in der Therapie ARID1A-defizienter Pankreaskarzinome
(2025-04-14)Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignant tumors and is expected to be the second most common cause of cancer-associated death after lung cancer by 2030. A major reason for the poor ... -
Mechanismen der Tachykardie-induzierten Kardiomyopathie im humanen Myokard und Kardiomyozyten
(2025-04-14)Tachycardia-induced cardiomyopathy (TCM) describes a reversible form of left-ventricular dysfunction based on a persisting tachycardia. Its clinical impact is relevant but often underestimated, hence its mechanisms remain ... -
Die einwärtsgleichrichtenden Kaliumströme IK1 und IK,ACh in atrialen Kardiomyozyten aus humanen induzierten pluripotenten Stammzellen und ihr Remodelling unter in-vitro Feldstimulation
(2025-04-09)Atrial fibrillation is the most common sustained supraventricular arrhythmia in humans and is associated with an immense increase in the risk of stroke. Many key questions about the development and therefore also the ... -
Differenzierung histologischer Subtypen des Nierenzellkarzinoms anhand multiphasischer CT: Eine Radiomics und Machine Learning Studie
(2025-04-08)The number of renal cell carcinoma (RCC) diagnoses has increased since the late 1990s, primarily due to incidental findings. Early detection complicates the radiological differentiation of the three most common RCC ... -
Faktoren, die Studierende im Praktischen Jahr bei der zukünftigen Facharztwahl beeinflussen
(2025-04-08)The following dissertation shows factors that influence students in choosing their future specialty in medicine. Qualitative content analysis can be chosen as a form of analysis of interviews. Referring to the elaborated ... -
Die Wirksamkeit eines 6-wöchigen hochfrequenten, standardisierten Sportprogramms auf die Erkrankungsschwere in drei Gruppen psychiatrischer Störungen
(2025-04-03)Depression, addiction syndromes and schizophrenia are three of the most common severe psychiatric disorders. For all three disorders, there are established treatment regimes and guidelines for diagnosis and treatment. The ... -
Quantitative T1-Kartierung des Cerebrums und quantitative Liquor-Flussmessungen bei Patienten mit idiopathischem Normaldruckhydrozephalus und Idiopathischer Intrakranieller Hypertension
(2025-04-03)Idiopathic normal pressure hydrocephalus (iNPH) and idiopathic intracranial hypertension (IIH) are important cerebral disorders with impaired production, circulation or resorption of cerebrospinal fluid (CSF). Despite ...