Human- und Zahnmedizin
Recent Submissions
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Auswirkungen der Maskenpflicht auf die Arzt-Patienten-Kommunikation bei Patienten mit Tumoren im Mund-, Kiefer- und Gesichtsbereich
(2025-04-29)To contain the rapid spread of SARS-CoV-2, the mandatory wearing of face masks was a key component of COVID-19 safety measures during the pandemic. This mask mandate was repeatedly subject to controversial debate. As a ... -
Varianten im Dihydropyrimidin-Dehydrogenase-Gen (DPYD) bei Patienten mit Rektumkarzinomen unter adjuvanter, 5-FU-haltiger Chemotherapie – eine monozentrische Analyse aus der GAST-05-Studie
(2025-04-29)In this monocentric posthoc study the impact of occult mutational DPYD status in patients with adenocarcinomas (stages ≥ II) of the upper rectum was investigated towards the occurrence of CTC-AEs (Common-Toxicity-Criteri ... -
FBRSL1 und seine Assoziation zum Polycomb-Komplex: Interaktionspartner und transkriptionaler Einfluss auf Zielgene
(2025-04-28)Zusammenfassung Englisch At the University of Göttingen three children with similar congenital symptoms were genetically tested, and variants in the FBRSL1-Gene were found in all of them. During my thesis work, I tested ... -
Dysfunktionen des autonomen Nervensystems bei adulter Aufmerksamkeitsdefizit- / Hyperaktivitätsstörung
(2025-04-28)Autonomic system dysfunction has been reported in children and adolescents with attention deficit hyperactivity disorder (ADHD) and may be related to their behavioural characteristics. However, findings are inconsistent ... -
Neurodegenerationsmarker im Verlauf eines 6-wöchigen hochfrequenten standardisierten Sportprogramms (SIWAS) in 3 Gruppen Psychiatrischer Erkrankungen
(2025-04-28)This study investigated the effects of a six-week, structured physical exercise program on neurodegenerative biomarkers in patients with schizophrenia, depression, or substance use disorders. A total of 61 participants ... -
Proteomische Analyse des kleinzelligen Lungenkarzinoms
(2025-04-28)Small cell lung carcinoma belonging to the group of neuroendocrine tumors of the lung is an aggressive and rapidly progressing tumor disease with a poor prognosis. Significant progress in the treatment of patients with ... -
Evaluation der nicht-invasiven Leberelastizitäsmessung mittels 2D-Scherwellen-Elastographie (LOGIQ E9 shear wave elastography) im Verlauf der Gewichtsreduktion bei Adipositas im Rahmen des Therapiekonzeptes OPTIFAST®-52
(2025-04-24)Due to its high prevalence and potentially asymptomatic course, non-alcoholic fatty liver disease (NAFLD) remains a challenge in medicine. NAFLD may progress to non-alcoholic steatohepatitis (NASH) and eventually lead to ... -
Verschlussrate sowie intra- und postoperative Komplikationen nach Makulalochchirurgie
(2025-04-23)The full thickness macular hole is a vision threatening condition and without treatment the risk of permanent and severe vision loss is high. Currently, the only established and standard treatment for full thickness macular ... -
Endoplasmatischer Retikulum-Stress im Zellkulturmodel für chronische Muskelentzündungen
(2025-04-23)Background: Inclusion body myositis (IBM) is an acquired myopathy in individuals over the age of fifty. It is characterized by progressive muscle atrophy and weakness that leads to severe disability. Currently there is no ... -
Longitudinal Structural Voxel based Morphometry of 1.5 tesla MRI in early Parkinson’s disease
(2025-04-23)Parkinson’s disease is a multisystemic, progressive neurodegenerative disorder characterized by the gradual loss of dopaminergic neurons in the substantia nigra, resulting in a wide range of motor and non-motor symptoms ... -
Morphologische und mechanistische Analyse des Wachstums retinaler Ganglienzellen unter Einfluss von Mikrofluidik in vitro
(2025-04-22)Replacing retinal ganglion cells (RGCs) in a degenerated optic nerve is not yet possible but may become feasible in the future through stem cell transplantation. Microfluidic fluid streams, presumably present in the optic ... -
Differentialdiagnostische Abgrenzung des Panayiotopoulos-Syndroms von der Migräne
(2025-04-22)Migraine is among the most common primary headache syndromes in childhood and adolescence. Panayiotopoulos syndrome (PS) (also known as early-onset benign occipital seizure susceptibility syndrome (EBOSS) or self-limited ... -
Prognostische Bedeutung von hochsensitivem Troponin I bei normotensiven Patienten mit akuter Lungenembolie
(2025-04-17)This study investigated the prognostic significance of high-sensitivity troponin I (hsTnI) in normotensive patients with acute pulmonary embolism (PE). The goal was to identify an optimized cutoff value for hsTnI for risk ... -
Einfluss von Elektrolytkonzentrationen auf Qualitätsparameter bei Elektrokonvulsionstherapie
(2025-04-14)The effectiveness of electroconvulsive therapy depends on achieving a generalized seizure. Several strategies exist on how to improve seizure quality. From clinical observations we know that electrolyte disturbances often ... -
Evaluation der Behandlung mit KAN0438757 in Kombination mit verschiedenen Chemotherapien im glykolytischen und lipogenen Subtyp des duktalen Pankreaskarzinoms
(2025-04-14)Despite current treatment options, the 5-year survival rate for patients with pancreatic ductal adenocarcinoma is below 10%. This highlights the relevance of new therapeutic approaches. Pancreatic ductal adenocarcinoma, ... -
Zur Bedeutung von Typ-D-Persönlichkeit und Bindungsstil bei Patient*innen mit kardiovaskulären Risikofaktoren oder Herzinsuffizienz aus der Diast-CHF-Studie
(2025-04-14)OBJECTIVE: Although the prevalence of depression, anxiety and vital exhaustion in cardiac patients is high and can contribute to the deterioration of their health, mental disorders are often underdiagnosed and inadequately ... -
In-vivo-Diagnostik und Therapiemonitoring mittels 18F-FDG-Positronenemissionstomographie im Tg4-42 Alzheimer-Mausmodell
(2025-04-14)In this study, two groups of Alzheimer's model mice of the Tg4-42 type were injected intravenously with 18F-FDG at the age of 7 months and 3 months. Subsequently, the 18F-FDG uptake of the brain was visualized by PET/MRI. ... -
Der Einfluss von 8-Prenylnaringenin und Alendronat in Kombination mit vertikaler Ganzkörpervibration auf den Wirbelkörper des osteopenischen Rattenmodells
(2025-04-14)Osteoporosis is a systemic disease of the skeleton with reduced bone stability and increased fracture risk. Due to rising osteoporosis-related healthcare costs, the disease and its treatment represent an increasing health ... -
Gesundheitsbezogene Lebensqualität von Kindern nach Schädel-Hirn-Trauma: Vergleich der Kinder- und Elternperspektive
(2025-04-14)Pediatric Health-Related Quality of Life (HRQoL) as a measure of subjective well-being and functional capacity has gained increasing importance in recent years. However, the HRQoL of children and adolescents following a ... -
Charakterisierung der LIFR/STAT3-Inhibition in der Therapie ARID1A-defizienter Pankreaskarzinome
(2025-04-14)Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignant tumors and is expected to be the second most common cause of cancer-associated death after lung cancer by 2030. A major reason for the poor ...