Human- und Zahnmedizin
Recent Submissions
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Ampicillin und Cefotaxim in der Intensivmedizin: Eine retrospektive Plasmaspiegel-Analyse
(2025-11-18)Ampicillin and cefotaxime are among the antibiotics most commonly used in critically ill patients. However, their use in this context has only been sporadically described and analyzed in the scientific literature to date. ... -
Untersuchung zur Tragedauer von Okklusionsschienen bei Patient*innen mit myofaszialen Schmerzen
(2025-11-18)This study examined the compliance of patients with myofascial pain with occlusal splint therapy using objective wear time recording. The intraoral wear time of the splints was measured over 90 days using integrated ... -
Seltene pädiatrische nicht-diffuse hochgradige Gliome: Epidemiologische und klinische Charakterisierung von anaplastischen Gangliogliomen, anaplastischen pleomorphen Xanthoastrozytomen und pilozytischen Astrozytomen mit Anaplasie
(2025-11-18)Pediatric high-grade gliomas (pHGG) are rare and aggressive central nervous system tumors in children and adolescents. Non-diffuse subtypes such as anaplastic ganglioglioma, anaplastic pleomorphic xanthoastrocytoma, and ... -
Vorhof-Funktion bei Patienten mit asymptomatischer Herzinsuffizienz
(2025-11-12)Background: Early atrial alterations in asymptomatic systolic heart failure (NYHA I) remain insufficiently defined. We aimed to quantify left- (LA) and right-atrial (RA) function using cardiovascular magnetic resonance ... -
Kohortenanalyse von Patienten mit chronischer Immunneuropathie an der Klinik für Neurologie
(2025-11-12)Chronic immunoneuropathies, particularly Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP), are rare disorders characterized by potentially severe neurological impairment. Given the risk of irreversible ... -
Untersuchung zu Einflussfaktoren auf das Therapieergebnis und Rezidivverhalten von operativ resezierten intrakraniellen Meningeomen
(2025-11-10)This thesis investigates the influence of different factors such as e.g. histological grade, patients' demographic data, peritumoral edema, tumor volume, surgical grade of resection and radiation on therapy outcomes and ... -
Retrospektive Analyse der Patienten mit chronischem Subduralem Hämatom nach Embolisation der Arterie meningea media versus offene Operation
(2025-11-06)This dissertation presents a retrospective analysis comparing outcomes of patients with chronic subdural hematoma (cSDH) treated either by middle meningeal artery embolization (MMAE) or conventional surgical evacuation. A ... -
Multicentric evaluation of the online elective Culinary Medicine in the winter semester 2020/2021 and summer semester 2021
(2025-11-05)Non-communicable diseases (NCDs) are one of the greatest challenges in modern medicine. NCDs include cardiovascular diseases, cancer, chronic pulmonary diseases, and diabetes. All of these diseases are associated with four ... -
Stellenwert der Lymphadenektomie im Rahmen der Ösophagusresektion bei Ösophaguskarzinomen und Karzinomen des gastroösophagealen Übergangs
(2025-11-05)Esophageal carcinoma, a malignant neoplasm of the upper gastrointestinal tract, is among the most aggressive cancers in terms of prognosis and mortality. While squamous cell carcinoma remains the most common histological ... -
Vergleichende Untersuchung von Art und Häufigkeit von Artikulationsmustern bei stotternden und bei nicht stotternden Probanden mittels Echtzeit-MRT
(2025-11-03)The genesis of primary non-syndromic stuttering remains, despite groundbreaking advances in stuttering research in the 21st century, one of the unresolved medical mysteries. In particular, the examination of the internal ... -
Morphological and functional consequences of an AAV-mediated Foxo3 knockdown on C2C12 myoblasts
(2025-11-03)Sarcopenia is a common disease in the elderly and hospitalized population, leading to a higher risk of falling and hospitalization, resulting in increased healthcare costs and significantly reduced quality of life. Current ... -
Untersuchungen zu Biomarkern der neuronalen Zellschädigung bei Autoantikörper-assoziierten psychiatrischen Syndromen
(2025-11-03)There is currently controversy surrounding whether psychiatric disorders associated with neural autoantibodies lead to neuronal cell damage. Therefore, the aim of this study was to answer the question of whether psychiatric ... -
In vitro testing of histone deacetylase inhibitors (HDACi) in combination with temozolomide radio-chemotherapy as a treatment strategy for pediatric high-grade gliomas (pedHGG)
(2025-11-03)Pediatric high-grade gliomas (pedHGG) are highly malignant pediatric brain tumors associated with a fatal prognosis and include, among others, diffuse intrinsic pontine gliomas (DIPG), which in 65 % carry an H3.3K27M ... -
Etablierung und Charakterisierung von Zervixkarzinomzelllinien mit stabiler Überexpression des G-gekoppelten Östrogenrezeptors (GPER1)
(2025-10-29)Cervical cancer (CC) remains the fourth most common malignancy among women worldwide, despite effective HPV vaccination strategies. CC can be classified into different histological subtypes. The majority of cases are ... -
Die Rolle von Vitamin K2 in der Osteoporose-Diagnostik – Etablierung neuer Messparameter
(2025-10-28)Osteoporosis is a disease of bone metabolism that can lead to frequent fractures and thus a reduced quality of life. Diagnosis primarily involves bone density measurement using DXA and various laboratory parameters. Vitamin ... -
Ergebnisse nach Zirkumzision bei Kindern – welche Faktoren beeinflussen die Elternzufriedenheit?
(2025-10-28)In Germany, slightly more than 100,000 circumcisions are performed annually, with 10.9% of boys aged 0–17 years being circumcised. The decision to circumcise a child often presents a challenge for parents. Medically indicated ... -
Multimodal structural analysis of tissue specimens using x-ray phase contrast micro-CT based 3D virtual histology
(2025-10-24)Histological analysis ofhumanand animal tissues is fundamental tomedical diagnosis and biomedical research, providing insights into disease mechanisms, progression, and treatment response. Traditional histology, involving ... -
Einfluss der körperlichen Fitness auf die Belastung und auf die individuelle Leistungsfährigkeit während der Herzdruckmassage ohne versus mit Leistungskorrektur
(2025-10-24)Background: High-quality external chest compressions (ECC) are essential for successful cardiopulmonary resuscitation (CPR). Maintaining adequate compression depth and rate is physically demanding and affected by rescuer ... -
Untersuchung der Phagozytosefähigkeit humaner Vollblutleukozyten in Abhängigkeit von der Stimulation durch Gummi arabicum
(2025-10-24)Background: Gum arabic, a polysaccharide exudate from Acacia senegal (L.)Willdenow trees, has already been used by African native people in natural medicine. Methods: Using whole-blood samples from young (20–35 years) ... -
Auswirkung veränderter Calciumsensitivität von Myofilamenten auf die Anfälligkeit und Aufrechterhaltung von Episoden des Vorhofflimmerns
(2025-10-24)Atrial fibrillation is the most common atrial arrhythmia and shows an age-dependent increase in incidence. In many cases, diagnosis is only made after the occurrence of complications such as stroke or heart failure. Since ...