Human- und Zahnmedizin
Recent Submissions
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Morphologische Normwerte von Augenmuskeln (M. levator palpebrae superioris und M. rectus superior) im Vergleich zu Extremitätenmuskeln (M. deltoideus und M. quadriceps femoris)
(2025-01-23)The function of the eye muscles enables them to perform fast and precise movements while also exhibiting a pronounced resistance to fatigue. Although the structure and function of eye muscles differ from the limb musculature, ... -
Stabilität der Synuklein Proteine
(2025-01-22)The protein α-synuclein, which belongs to the synuclein family along with β- and γ-synuclein, plays a crucial role in the pathogenesis of Parkinson's disease. β-synuclein is also etiopathologically linked to the development ... -
Einfluss selektiver Androgen- und Östrogenrezeptormodulatoren in Mono- und Kombinationstherapie auf die Knochensubstanz der osteopenen, männlichen Ratte
(2025-01-21)Osteoporosis is one of the systemic skeletal diseases characterized by a loss of bone mass, leading to increased bone fragility and susceptibility to fractures. The World Health Organization (WHO) classifies osteoporosis ... -
Interaktion zwischen ATG2, ATG9 und WIPI4 und ihre Rolle in der Autophagosommebranbildung
(2025-01-21)Autophagy is a cellular recycling mechanism involved in various physiological functions, such as homeostasis, cellular stress response, and nutrient deprivation. A key step in autophagy is the formation of the autophagosome ... -
Neuronal-exosomes biomarkers from plasma of neurodegenerative disease patients
(2025-01-21)The dementia group of diseases share some features such as the degeneration of neurons, which leads to progressive and irreversible loss of cognitive functions. Since almost 10 years, dementia syndromes were declared a ... -
Körperregionen-spezifisches Keim- und Resistenzspektrum unfallchirurgischer/orthopädischer/ plastisch chirurgischer Patienten in einer Klinik der Maximalversorgung
(2025-01-20)Musculoskeletal infections and bacterial arthritis are frequent and dreaded complications of surgery. To optimize the treatment of postoperative infections, it is useful to know the pathogen spectrum of the individual body ... -
Mechanismus von Glukokortikoiden in der Regulation des Immunmetabolismus humaner T-Zellen
(2025-01-20)Glucocorticoids are used to treat numerous inflammatory diseases. But despite decades of research, their exact mechanisms of action remain incompletely understood. Glucocorticoids influence the activity and effector functions ... -
Assessing the stratification and the prognostic value of SARS-CoV-2 routine data in the context of advanced hospitalization rate 2.0 (HR 2.0)
(2025-01-20)Background: Machine learning is becoming increasingly popular in the field of infection prevention and control. This is particularly evident in the context of surveillance, where screening clinical prediction rules (CPR) ... -
Relevanz von methylierten DNA-Fragmenten als nicht-invasiver Biomarker beim Nierenversagen
(2025-01-20)Epigenetic modifications, particularly DNA methylation, play a central role in the progression of acute and chronic kidney diseases. Early identification of at-risk patients and timely initiation of preventive measures are ... -
Patienten mit fortgeschrittenen hämatologischen Grunderkrankungen in der Spezialisierten Ambulanten Palliativversorgung (SAPV)
(2025-01-17)Patients with advanced haematological malignancies in non-curative settings suffer from complex physical symptoms and psychosocial distress, comparable to patients with solid tumour entities. Nevertheless, numerous problems ... -
Evaluation des Krankheitsverlaufs von Patienten mit Diabetes mellitus Typ 2 der Diabetesambulanz der UMG anhand laborchemischer und klinischer Parameter – eine retrospektive Analyse des Zeitraums 2014 bis 2021
(2025-01-17)The aim of this doctoral thesis was to investigate the disease progression and treatment courses of patients with type 2 diabetes at the diabetes outpatient department of University Medical Center Göttingen between the ... -
Untersuchung plasmabasierter Kompositbiomarker in der Differentialdiagnostik von Alzheimer-Demenz und Vaskulärer Demenz
(2025-01-17)Due to demographic change, dementia is not only at the center of medical research but is also becoming increasingly important in the health economic and social debate. Taking that into consideration, dementia diagnostics ... -
Persönlichkeit und Inkongruenzerleben als Determinanten des Effekts eines 6-wöchigen hochfrequenten, standardisierten Sportprogramms (SIWAS-Studie)
(2025-01-17)The therapeutic effect of exercise on mental illness has already been shown many times and for patients with various mental illnesses, especially depression (Knapen et al. 2014, Dauwan et al. 2015). However, little research ... -
Die Rolle der CHD1 Depletion im Prostatakarzinom bei der epithelial zu mesenchymalen Transition und der ossären Metastasierung
(2025-01-17)In the treatment of advanced prostate cancer with androgen deprivation, almost all patients develop castration resistance after some time. The tumor growth continues despite ongoing therapy. In these castration-resistant ... -
Molecular assembly of auditory ribbon synapses in mice
(2025-01-17)Auditory ribbon synapses are specialized structures in the inner hair cells (IHCs) that enable rapid neurotransmitter release, making them essential for precise signal transmission in the auditory system. However, insights ... -
Erhebung echokardiographischer Parameter zur Quantifizierung der Pulmonalklappeninsuffizienz und Vergleich zur Schweregradbeurteilung im MRT
(2025-01-17)Pulmonary regurgitation (PR) is a common valvular disease in patients with congenital heart defects (CHD) and contributes to morbidity and mortality in the long-term. This retrospective analysis invastigated wether ... -
Exploring the role of Cytoglobin (CYGB) in melanoma pathobiology
(2025-01-17)Skin cancer is one of the most common malignancies worldwide, with melanoma being the deadliest form. Although both targeted therapies inhibiting the MAPK pathway and immunotherapy have improved the prognosis of patients ... -
Biomechanische Untersuchungen ventraler Osteosyntheseverfahren bei Densfrakturen Anderson und D’Alonzo Typ II
(2025-01-14)The data on the use of single- or double-screw techniques for anterior osteosynthesis of type II odontoid fractures is inconclusive and contradictory. Although the double-screw technique appears to offer more rotational ... -
Untersuchung der sprechbezogenen Veränderungen der Erregbarkeit im primären Motorkortex bei Stotternden und Kontrollprobanden mittels transkranieller Magnetstimulation
(2025-01-14)Transcranial magnetic stimulation reveals a lack of reduction of intracortical inhibition of the tongue primary motor cortex in adults who stutter as compared to fluent speakers: Original neurogenic non-syndromic ... -
Analyzing Pedicle Screw Strength with Finite Element Method in Relation to Vertebral Bone Properties
(2025-01-13)Vertebral fractures are increasingly prevalent in our aging population. Conservative treatments and minimally invasive surgeries are standard, but posterior fixation systems like pedicle-screw-rod constructs face failure ...