Human- und Zahnmedizin
Recent Submissions
-
Ergebnisse mikroskopischer und röntgenologischer Untersuchungen zur Differentialdiagnose von Krankheitsspuren an ausgewählten Skeletproben der frühbyzantinischen Kinderpopulation vom Arslantepe/Malatya (Türkei)
(2026-01-16)This study shows that the microscopic analysis of bone samples can provide reliable diagnoses of disease burdens. In this case, the analysis was used to study an early Byzantine child population in southern Central ... -
Effect of microglia depletion on white and gray matter inflammation in myelin mutant mice
(2026-01-16)This thesis aimed to characterize microglia phenotype following CSF1R inhibitor PLX5622 treatment in the catatonia mouse model Cnp knockout (Cnp-/-). Prior research established Cnp-/- mice as a translational model for ... -
Die nukleare Translokation des Kalziumbindenden-Proteins Calbindin-1 und dessen Rolle bei der Kalziumhomöostase in den distalen Tubuluszellen der Niere.
(2026-01-16)The nuclear translocation of the calcium binding protein calbindin-1 and its role in the calcium-homeostasis in kidney distal tubule cells Calcium (Ca2+) plays a key role in many physiological processes like hormone ... -
Analyse der Aktivitäten verschiedener Gerinnungsfaktoren im Verlauf unter einer venovenösen extrakorporalen Membranoxygenierung
(2026-01-16)Acute respiratory distress syndrom (ARDS) can lead to severe acute hypoxemic respiratory failure. When conventional management strategies failed veno-venous extracoporeal membrane oxygenation (vvECMO) can be a rescue ... -
Liefern kapilläre Blutentnahmen, die über Postversand ins Labor verschickt wurden, vergleichbare Messergebnisse gegenüber Laboranalysen aus venösen Blutentnahmen in der Hausarztpraxis?
(2026-01-15)Introduction: New upper-arm devices allow patients to collect capillary self-blood samples on their own. Thanks to improved laboratory measurement technologies in recent decades, much smaller sample volumes are now required, ... -
Retrospektive Analyse lasergestützter Kalkulationen von Intraokularlinsen mittels unterschiedlicher Berechnungsformeln
(2026-01-14)Background: The calculation of the refractive power of the intraocular lens (IOL) to be implanted is a crucial step in cataract surgeries. Various formulas that utilize different biometric parameters are available. ... -
Lipidhomöostase und deren Maladaptation im zentralen Nervensystem
(2026-01-14)Multiple sclerosis is an autoimmune, demyelinating disease that is highly relevant in terms of both its prevalence and its socioeconomic significance. Pathophysiologically, there is a complex, dynamic interaction between ... -
Studie zum klinischen Outcome von Patienten nach Wirbelkörperersatz an der ventralen Brust- und Lendenwirbelsäule
(2026-01-13)This retrospective study evaluates long-term outcomes after anterior vertebral body replacement with bisegmental fusion in 76 patients with lower thoracic and lumbar spine fractures. No significant differences were found ... -
Eine randomisierte, verblindete, placebokontrollierte prä-klinische Studie zur antifibrotischen und nephroprotektiven Wirkung einer Kombinationstherapie mit dem monoklonalen Antikörper Actinab und dem ACE-Inhibitor Ramipril am Alport-Mausmodell
(2026-01-08)Alport syndrome is a hereditary disorder of type IV collagen that leads to impaired glomerular filtration function in the kidneys. The current standard treatment is early administration of an ACE inhibitor. In this study, ... -
Multimorbidität als Prädiktor für eine stationäre Aufnahme in der klinischen Notfall- und Akutmedizin
(2026-01-08)Background Parallel to demographic trends, an increase of multimorbid patients in emergency and acute medicine is prominent. To define easily applicable criteria for the necessity of inpatient admission, a hierarchical ... -
Vorstellungen guten Lebens von Erwachsenen mit chronischen Herzerkrankungen
(2026-01-06)Background: Quality of life is established in medicine as one of three legally defined endpoints and is typically assessed from the patient’s perspective across physical, psychological, and social dimensions. However, this ... -
Ätiologie und Häufigkeit pathologischer Veränderungen an den Skeletfunden der neolithischen Population aus Völlinghausen
(2026-01-06)Palaeopathology is an interdisciplinary field situated at the interface of (dental) medicine, anthropology, and archaeology. As the only contemporary witnesses, human remains serve as primary sources in the sense of ... -
Die Bedeutung des C-reaktiven Proteins in der Diagnostik von postoperativen periprothetischen Infektionen nach Primärimplantation von Hüftgelenksendoprothesen
(2026-01-06)The primary objective of this doctoral thesis was to develop a cost-efficient diagnostic tool for the detection of postoperative periprosthetic joint infection (PJI) following primary total hip arthroplasty (THA). Additionally, ... -
Durchführbarkeit und Wirksamkeit eines kollaborativen Behandlungsansatzes in der Sekundärprävention der Koronaren Herzerkrankung
(2026-01-06)Adequate management of cardiovascular risk factors (RFs) is important in the secondary prevention of coronary heart disease (CHD), but in practice it is often not easy to achieve. In the USA, the blended collaborative care ... -
Langfristiger Effekt einer Lungenarterienembolie auf das Mortalitätsrisiko
(2026-01-06)While numerous studies have investigated short-term outcomes after pulmonary embolism (PE), long-term mortality remains insufficiently studied. The objectives were investigate long-term outcomes in an unselected cohort of ... -
Einfluss der Aminosäure Phenylalanin an Position 244 des organischen Kationentransporters OCT1 auf die Transportaktivität
(2026-01-06)Membrane transporter proteins such as OCT1 from the SLC family are important for the distribution and homeostasis of drugs and endogenous substances in tissues. OCT1 is known for its polyspecificity, transporting at least ... -
Prä- und Posthomogenisierungsfärbung mit Antikörpern und Nanokörpern bei X10heat-Expansionsmikroskopie
(2026-01-06)Background: Conventional light microscopy is constrained by the diffraction limit and cannot resolve structures smaller than ~200 nm. Super-resolution microscopy (SRM) techniques such as STED, STORM, PALM, and SIM overcome ... -
Validierung einer deutschen Version des Central Sensitization Inventory (CSI-GE)
(2026-01-06)Central sensitization is considered an important factor in the development and maintenance of various chronic pain syndromes. Quantifying this process is challenging. The Central Sensitization Inventory (CSI) was developed ... -
Diagnostische Leistungsfähigkeit nichtinvasiver Pränataltests zur Bestimmung fetaler Merkmale des Rh-Blutgruppensystems
(2026-01-06)Over the past approximately 25 years, analysis of cell-free fetal DNA (cffDNA) from maternal plasma has enabled the non-invasive assessment of genetically determined fetal characteristics. Non-invasive prenatal testing ... -
Häufigkeit der intra- und frühen postoperativen Blutungskomplikationen bei Glaukomoperationen in Abhängigkeit von gerinnungshemmenden Substanzen
(2026-01-06)With the increasing age of the population, the number of patients requiring ophthalmologic care continues to rise. Comorbidities and pre-existing conditions often necessitate treatment with antithrombotic medication, which, ...