Dokumente Fakultät für Biologie und Psychologie (inkl. GAUSS) nach Gutachter "Tittmann, Kai Prof. Dr."
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Structural characterization of human spliceosome activation by cryo-EM
(2022-01-27)Eukaryotic genes are transcribed as precursor mRNA (pre-mRNA), in which coding regions (exons) are interrupted by non-coding regions (introns). Introns are excised and exons are ligated together in a two-step process ... -
Structural characterization of the lysosomal 66.3 kDa protein and of the DNA repair enzyme Mth0212 by means of X-ray crystallography
(2009-06-17)This PhD thesis is divided into two parts both dealing with structural characterization of macromolecules by means of X-ray crystallography. Part I concerns the lysosomal 66.3 kDa protein ... -
Structural characterization of the minimal human RISC-loading complex
(2014-03-07)Gene expression is the prerequisite for protein biosynthesis in all cells. Rapid and fine-tuned control of gene expression in response to environmental changes is of great importance. A major gene regulation mechanism in ...