Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Referee "Wimmer, Ernst A. Prof. Dr."
Now showing items 21-40 of 94
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Effekte der Klasse-3 Semaphorine auf die Entwicklung und Progression maligner Hirntumoren
(2011-03-25)The neuropilins are endothelial cell surface receptors that function as receptors for the angiogenic factors of the vascular endothelial growth factor (VEGF) family. They also function as ... -
Electron microscopic localization of tagged proteins in the yeast S. cerevisiae spliceosomal U4/U6.U5 trisnRNP
(2008-10-30)Pre-mRNA splicing is catalyzed by a macromolecular machine called spliceosome . The spliceosome is assembled in a stepwise manner from the small nuclear ribonucleoprotein particles (snRNPs), ... -
Establishment of retinoic acid gradients in the early development of Xenopus laevis
(2009-07-16)Retinoic acid (RA) is an important morphogen that regulates many biological processes, including the development of the central nervous system (CNS). Its synthesis from vitamin A (retinol) ... -
Evolution of caudal translational repression in higher insects
(2011-03-03)The anterior patterning factor bicoid (bcd) mediates translational repression of caudal (cad) in Drosophila embryos and is an evolutionary novelty present only in higher dipterans. ... -
Exploring morphological innovation and diversification: Analysis of genes involved in gin-trap formation and antenna remodeling during metamorphosis in Tribolium castaneum
(2017-08-18)How morphological traits originate and diversify is a central question in evolutionary biology. Insects are the most diverse group of animals on the planet and over 80% of insect species belong to the subgroup of holometabola. ... -
Expression screen for Wnt signaling-like phenotypes identifies Fam132b as a novel inhibitor of BMP signaling in Xenopus
(2014-03-13)The canonical Wnt signaling pathway is known to regulate multiple developmental events,including development of the digestive tract. In this study, we wanted to systematically analyze the role of the Wnt/β-Catenin signaling ... -
Functional analysis of embryonic brain development in Tribolium castaneum
(2011-08-31)The brain is one of the most complex organs in animals. It allows the coordination of complex operations like orientation and directed movements. In insects, a structure in the brain has ... -
Functional Analysis of Mars (CG17064) in Drosophila Development
(2010-03-31)The formation of the mitotic spindle is controlled by the microtubule organizing activity of the centrosomes and by the effects of chromatin-associated Ran-GTP on the activities of spindle ... -
Functional analysis of the Bazooka protein in the establishment of cell polarity in Drosophila melanogaster
(2009-10-14)Components of the PAR/aPKC (partitioning-defective / atypical protein kinase C) complex have been found to play a key role in the establishment and maintenance of cell polarity in various ... -
Functional analysis of the septate junction protein complex in Drosophila melanogaster
(2019-04-10)Body cavities and external surfaces of metazoic organisms are covered with sheets of epithelial cells that act as physical and chemical barriers. Epithelial tissues divide the body into differentiated compartments with ... -
Functional Analysis of Two Major Sperm Tail Proteins Identifies ODF1 as Being Essential for the Tight Linkage of the Sperm Head to the Tail via SPAG4 and ODF2 as A Component of the β-catenin Destruction Complex
(2015-04-02)In the mammalian sperm tail, the outer dense fibers (ODFs) are accessory fibers accompanying the axonemal tubuli doublets on their outer site. The ODFs are composed of at least 14 polypeptides of which only a few have been ... -
Functional characterization of m Satb1 and Satb2 in the developing neocortex
(2008-11-21)Satb1, special AT-rich sequence binding protein 1, is a transcription factor that is involved in the regulation of tissue-specific organization of chromatin. It is localized at nuclei ... -
Functional characterization of the gene schlappohr (CG7739) during Drosophila development
(2010-08-11)In this study the role the gene schlappohr (shlp) during development of Drosophila melanogaster (Drosophila) was investigated. shlp encodes a evolutionary highly conserved protein with ... -
Functional Characterization of the Histone Methyltransferase and Methyl DNA Binding Protein MDU and its Role in Epigenetic Regulation of Rbf Gene in Drosophila Melanogaster
(2008-12-16)The methylation of genomic DNA and histones is paramount for the execution of epigenetic events such as imprinting, gene dosage compensation, and gene silencing. Studies in fungi, plants ... -
Functions of TGF-β2 and GDNF in the Development of the Mouse Nervous System: Evidence from Double Mutant Mice
(2006-11-08)Abstract: A major area of investigations in neuroscience is directed at understanding factors that participate in neural survival versus death. A number of neurotrophic growth factors ... -
Die Funktion des Wnt Antagonisten XsFRP5 während der frühembryonalen Musterbildung des Entoderms in Xenopus laevis
(2008-05-08)In vertebrates the embryonic development of all endodermal organs follows conserved molecular mechanisms. Wnt signaling is supposed to play a key role during these processes. The gastrointestinal tract comprises the ... -
Die Funktion von Geminin beim Übergang von Neuro- zu Gliogenese in der Maus
(2008-12-10)The development of an embryo requires the precise control of temporal and spatial coordinated processes, regulating the cellular fate. Geminin was characterized as a bifunctional protein, ... -
Funktionelle Analyse des Transkriptionsfaktors Pitx3 während der Entwicklung dopaminerger Neuronen im murinen Mittelhirn
(2013-09-04)The transcription factor PITX3 is expressed only in postmitotic mDA neurons of the midbrain and shows a complete co-expression of TH in the VTA and the SN. At a loss to PITX3 expression (aphakia mouse) the mDA neurons of ... -
Funktionelle Analyse des Transkriptionsfaktors Uncx4.1 im murinen Mittelhirn
(2012-05-18)The development of the brain is a complex process, which involves a lot of finely regulated processes. The best known disease which is associated with the midbrain is morbus parkinson. In the last years a lot of effort was ... -
Funktionelle Analyse von MHC-Klasse-I-Genen der Rhesusaffen (<i>Macaca mulatta</i>)
(2008-09-01)This thesis focuses on the structure and function of rhesus macaque (Macaca mulatta, Mamu) major histocompatibility complex (MHC) class I genes. As the cellular immune response is at least ...