Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Referee "Figura, Kurt von Prof. Dr. Dr. h.c."
Now showing items 21-31 of 31
-
Role of Adaptor Proteins in MPR sorting
(2003-06-04)Mannose 6-phosphate receptors mediate sorting of lysosomal enzymes and thus play an important role in lysosomal biogenesis. They bind to the mannose 6-phosphate residues on the lysosomal ... -
Charakterisierung von SNARE-Proteinen in der Hefe Saccharomyces cerevisiae
(2003-05-14)SNARE proteins are involved in the fusion of transport vesicles with target membranes in all eukaryotes and form complexes in which 3 Q-SNAREs interact with one R-SNARE. In the first part ... -
Congenital Disorder of Glycosylation (CDG) - Ih
(2003-04-17)Die "Congenital Disorders of Glycosylation (CDG)" beschreiben eine schnell wachsende Gruppe von multisystemischen Erberkrankungen, die durch Mutationen in für die Biosynthese von Glykoproteinen ... -
Characterisation of Vti1b and Vti1a proteins and generation of knock-out mice.
(2002-07-09)Genomic DNA for Vti1b and Vti1a was isolated and the chromosomal regions characterised. Using targeted gene disruption mouse mutants lacking Vti1b constitutively were generated. It was shown ... -
Insulin-Like Growth Factor Binding Protein-6: Posttranslational modifications and sorting in polarized MDCK cells
(2002-07-02)The insulin-like growth factors (IGFs) promote proliferation, and differentiation of a variety of cell types. The IGF availability and interactions with specific cell surface IGF-receptors ... -
Isolation and characterization of Saccharomyces cerevisiae mutants for vacuolar import and autophagocytosis
(2001-11-01)The yeast vacuolar protein aminopeptidase 1 (Apelp) is synthesised as a cytosolic procursor that is transported to the vacuole via the cytoplasm to vacuole trnasport (Cvt) pathway. The ... -
Congenital Disorder of Glycosylation (CDG)-IIc: Eine retrovirale Expressionsklonierung identifiziert das CDG-IIc Syndrom (Leukozyten Adhäsionsdefekt II) als eine GDP-Fukose Transporter Defizienz
(2001-07-23)N-glycosylation is the most common modification of secretory and membrane-bound proteins in eukaryotic cells. In the last few years N-glycosylation obtained increased biomedical relevance ... -
Funktionelle Analyse von Isoformen der CAPS-Proteinfamilie
(2001-06-13)Endocrine, neural and exocrine cells posses a regulatory secretion pathway by which hormones, neurotranmittes and enzymes are released. This exocytosis process requires calcium, ATP and ...