Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Title
Now showing items 610-629 of 1726
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Functional characterization of CDY family proteins and their role in recognition of the heterochromatic histone H3K9me3 modification
(2010-01-14)In the nucleus of eukaryotic cells the DNA is wrapped around octamers of histone proteins containing two H2A-H2B dimers and one (H3-H4)2 tetramer. This entity represents the basic repeating ... -
Functional characterization of m Satb1 and Satb2 in the developing neocortex
(2008-11-21)Satb1, special AT-rich sequence binding protein 1, is a transcription factor that is involved in the regulation of tissue-specific organization of chromatin. It is localized at nuclei ... -
Functional Characterization of Neurexophilins in the Central Nervous system
(2002-09-04)Neurexophilins (Nphs) form a family of proteins that were discovered as components of the alpha-latrotoxin receptor, based on their strong binding to the synaptic membrane proteins ... -
Functional characterization of the gene schlappohr (CG7739) during Drosophila development
(2010-08-11)In this study the role the gene schlappohr (shlp) during development of Drosophila melanogaster (Drosophila) was investigated. shlp encodes a evolutionary highly conserved protein with ... -
Functional Characterization of the Histone Methyltransferase and Methyl DNA Binding Protein MDU and its Role in Epigenetic Regulation of Rbf Gene in Drosophila Melanogaster
(2008-12-16)The methylation of genomic DNA and histones is paramount for the execution of epigenetic events such as imprinting, gene dosage compensation, and gene silencing. Studies in fungi, plants ... -
Functional characterization of the human renal organic anion transporter 3 (hOAT3) and comparison to hOAT1
(2004-06-01)Renal secretion of organic anions is critically dependent on their basolateral uptake against the electrochemical gradient. Due to their localization, two transporters are likely involved, ... -
Functional diversity of mycorrhiza in relation to land-use changes and ecosystem functions
(2016-02-19)Managing forest ecosystems has a long tradition in Germany. However, the influence of this intervention on the most important symbiosis partners of the trees, mycorrhizal fungi, is poorly understood. The fungal partner ... -
Functional gene analysis in cultured vertebrate cells using siRNA mediated gene silencing
(2005-02-23)Gene expression can be silenced in a sequence-specific manner by use of small interfering RNAs (siRNAs) in a process that is known as RNA interference (RNAi). The application of RNAi ... -
Functional imaging of the anesthetized brain in primates and rodents
(2022-07-05)Understanding the brain is aided by visualizing neural activity over time. The most popular method for doing so in humans is functional magnetic resonance imaging (fMRI)—a method that tracks blood oxygenation as a proxy ... -
Functional neuroimaging of pathophysiological mesolimbic dopamine system and aberrant motivational salience in schizophrenia
(2017-06-16)Schizophrenia is a common and devastating psychiatric illness with prominent variability regarding its process, symptomatology and treatment response. The disorder is characterized by three broad types of symptoms including ... -
Functional organisation of the central complex of the grasshopper <i>Chorthippus biguttulus</i> in relation to sound production
(2008-05-27)The central complex is a major control neuropile for the situation specific selection of sound pattern of grasshoppers. The current thesis tries to investigate the role of different neurotransmitter systems in this brain ... -
Functional Phage Genomics of selected Taxa
(2019-06-26)This work reports the potential of a fully automated genome based phage prediction and classification method with ever-increasing amounts of sequencing data. Firstly, we present an approach we call ClassiPhage and ClassiPhages ... -
Functional properties and Ca2+-dependent feedback modulation of voltage-gated Ca2+ channels in glutamatergic nerve terminals of the mammalian auditory brainstem
(2012-03-02)The functional properties of mammalian presynaptic nerve endings remain elusive since most terminals of the central nervous system are not accessible to direct electrophysiological recordings. ... -
Functional properties of microglia in mouse models of Alzheimer’s disease
(2017-02-13)Microglia, resident macrophages of the CNS, execute various functions: they participate in oligodendrogenesis, neurogenesis, learning and behavior, phagocytose harmful material as well as tissue debris and mount crucial ... -
Functional Reconstitution of SLC18 Family Transporters
(2025-12-12)The Solute Carrier (SLC) family proteins are a diverse group of proteins performing many vital functions from bacteria to humans. Vesicular neurotransmitter transporters (VNTs) also belong to the SLC family. Based on ... -
Functional relevance of oligodendroglial CDC42 effector proteins CDC42EP1 and CDC42EP2 in myelin morphogenesis
(2025-11-12)Myelin sheaths are composed of multiple compacted membrane layers that tightly encase the underlying axon. Structural abnormalities of myelin indicate pathological processes and are frequently associated with neurological ... -
Functional Studies of SNAP-25 using a knock-out and rescue approach
(2006-11-01)The neuronal SNARE complex, consisting of SNAP-25, synaptobrevin and syntaxin, is required for presynaptic exocytosis of neurotransmitter-filled vesicles during synaptic transmission. However ... -
Functional studies on the transmembrane protein encoded by the TM20 gene in maize
(2002-05-03)In the course of the analysis of lachrima, a recessive, defective kernel, embryo-lethal mutation in Zea mays that blocks embryo and endosperm development at transition stage, a gene coding ... -
Functional study of potential sHSPs in Arabidopsis and tomato under environmental stress.
(2019-05-10)Small heat shock proteins (sHSPs) respond to many environmental stresses, stabilizing early unfolding protein intermediates and avoiding their irreversible aggregation. In plants, organellar sHSPs are a unique cellular ... -
Functions of TGF-β2 and GDNF in the Development of the Mouse Nervous System: Evidence from Double Mutant Mice
(2006-11-08)Abstract: A major area of investigations in neuroscience is directed at understanding factors that participate in neural survival versus death. A number of neurotrophic growth factors ...