Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Title
Now showing items 62-81 of 1725
-
Analyse von Translationsstarts in prokaryotischen Genomen mit Methoden des Maschinellen Lernens
(2007-12-11)Exact localization of prokaryotic translation initiation sites with automated prediction systems is still not completely solved. In this context, two approaches from the field of machine ... -
Analyse zur Rolle von pflanzlichen Wirkstoffen und Histondeacetylase-Inhibitoren auf Wachstumsfaktoren und deren Signalwege in Prostatakarzinomzellen
(2013-12-19)Prostate cancer (PCa) is the most frequently new diagnosed cancer entity and the third leading cause of cancer-related deaths of men in Germany. The options for therapy of PCa are restricted and most of them have strong ... -
Analyse zweier differentiell regulierter Terpensynthasen in <i>Arabidopsis thaliana</i>
(2008-09-05)Volatiles play an important role in plant-plant and plant-insect interactions and plants can emit different volatile bouquets to communicate with their environment. Thus, it can be ... -
Analysen zu TRIM-Genen in Primaten
(2009-04-16)In this work, the evolution of TRIM genes with identical domain structure as the antiviral TRIM5a was studied. The analysed TRIM genes form two clusters on chromosome 6 and 11 (MHC and 11p15 ... -
Analysen zum subzellulären Lokalisationsverhalten der atypischen Myrosinase PEN2 in Arabidopsis-Mikroben-Interaktionen
(2012-06-27)The atypical myrosinase PEN2 is a molecular component of nonhost resistance in Arabidopsis thaliana. Using a functional GFP-fusion protein revealed the localisation of PEN2 in the periphery of mobile membrane compartments, ... -
Analyses of improved long term memory in SHARP1 and SHARP2 double knockout mice
(2015-09-15)The transition of recent experiences into stable and remote memory traces is an important task that mainly occurs during sleep. Sleep-associated consolidation of remote long-term memory is based on cortical networks that ... -
Analyses of the Life Cycle of TLC1 and the Nuclear RNA Quality Control System in Saccharomyces cerevisiae
(2015-04-24)During genome replication, chromosomes undergo a progressive shortening of their ends. To counteract this loss, a complex named telomerase functions as a reverse transcriptase to elongate telomeres. In Saccharomyces ... -
Analysis of CERK1 ectodomain shedding and the role of XLG2 in cerk1-4 cell death execution
(2016-05-20)Conserved microbial signatures are perceived via plasma membrane localized pattern recognition receptors (PRRs). In Arabidopsis, perception of the fungal cell wall component chitin requires the LysM receptor-like kinase ... -
Analysis of Clp1-dependent UPR modulation in Ustilago maydis
(2019-06-13)The unfolded protein response (UPR) is a conserved signaling pathway, that is present in all eukaryotic cells and ensures endoplasmic reticulum (ER) homeostasis under stress conditions. In the phytopathogenic fungus U. ... -
Analysis of coiled coil domain containing 33 protein (CCDC33) and determination of infertility causes in mutant mouse line with the deletion of six germ cell-specific genes
(2013-02-27)Since most cases of male infertility remain idiopathic, analysis of the mechanism in which genes are involved in spermatogenesis control might help to better understand the reasons. This thesis consists of 2 parts concerning ... -
Analysis of CRM1- and Nup214- dependent nuclear export of proteins
(2012-12-12)Nuclear pore complexes (NPCs) are giant units of the nuclear envelope, mediating directional transport into and out of the nucleus. Nucleoporins are the main components of the NPC, and one third of them contain ... -
Analysis of ether-à-go-go potassium channel (Eag1) splice variants in melanoma cells
(2011-05-03)The human ether-à-go-go potassium channel (hEag1) can be detected in adult brain and in both, tumor cell lines and primary tumors. The physiological function of this channel in the brain ... -
Analysis of Myelin Membrane Growth in Oligodendrocytes
(2015-12-07)Nervous systems of mammalian organisms are composed of various cell types with different morphology, function and connectivity. Understanding this complicity from a molecular point of view requires the application of ... -
Analysis of Neuronal Diseases in the Model Organism <i>Aspergillus nidulans</i>
(2008-12-11)Neuronal diseases can include abnormal aggregation of key proteins or the dysfunction of transport processes during the development of nerve cells. Parkinson s disease (PD) is a neurodegenerative ... -
Analysis of peroxisomal turnover and myelin maintenance in mice with oligodendrocyte-specific MFP2-deficiency
(2016-11-02)Although caused by distinct genetic mutations, the peroxisomal disorders X-linked adrenoleukodystrophy (X-ALD), pseudoneonatal adrenoleukodystrophy (pseudo NALD), and neonatal adrenoleukodystrophy (NALD) share several ... -
Analysis of protein SUMOylation and its role in Alzheimer's disease using mouse models
(2017-04-26)Post-translational modifications serve as a cellular mechanism for the regulation of the activity, stability and localization of proteins. SUMOylation is a dynamic and reversible post-translational modification, which ... -
Analysis of small nucleolar (sno)RNA shuttling in Saccharomyces cerevisiae
(2025-08-07)Small nucleolar (sno)RNAs are a group of non-coding RNAs and can be classified into box C/D snoRNA and box H/ACA snoRNA based on their conserved sequences. They are further associated with snoRNA core proteins to form ... -
Analysis of the Antiviral Restriction Factor Shiftless in the context of HIV-1 Programmed –1 Ribosomal Frameshifting
(2024-07-05)The human immunodeficiency virus 1 (HIV 1) is responsible for a major global health crisis, the acquired immunodeficiency syndrome (AIDS) pandemic. Retroviruses integrate their genetic material into the genome of host ... -
Analysis of the Asc1p/RACK1 microenvironment in Saccharomyces cerevisiae using proximity-dependent Biotin Identification (BioID) and high-resolution mass spectrometry
(2017-10-11)The conserved ribosome-associated Asc1 protein of Saccharomyces cerevisiae forms a seven bladed β-propeller and binds to the head region of the 40S ribosomal subunit in close proximity to the mRNA exit tunnel. Asc1p is ... -
Analysis of the Cell Entry of Enveloped Viruses and Identification of Potential Intervention Strategies
(2022-05-19)Viruses are a continuous threat for the human population. They are causing tremendous damage to human health and economy. Not only zoonotic viruses, which jump from animals to humans, but also the spread of highly adapted ...