Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Title
Now showing items 633-652 of 1676
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Funktionelle Untersuchungen zum PTPN11-Genprodukt SHP2 und zu PTPN11 Mutanten, die dem Noonan-Syndrom zugrunde liegen
(2006-04-04)Noonan Syndrome (NS) [OMIM 163950] is an autosomal dominant disorder characterized by short stature, facial dismorphism, webbed neck, heart defects (most commonly pulmonic stenosis and ... -
Funktionen und Interaktionen von Homöodomänenproteinen während der Entwicklung des Rückenmarks
(2006-12-13)The dorsal spinal cord consists of several types of interneurons which process and relay sensory information from the periphery. These dorsal interneurons are generated during two distinct ... -
Funktionsanalyse der Ankyrin-repeat Proteine AKR2A und AKR2B in Arabidopsis thaliana
(2010-07-01)The ankyrin-repeat protein NtANK1 and the basic leucin zipper (bZIP)-transcription factor NtBZI-1 interact in tobacco. These proteins are involved in auxin-mediated gene activation ... -
Funktionsanalyse der Entwicklungskontrollgene Irx2 und Mash1 in der Maus.
(2002-10-01)The development of organism is controlled by transcription factors which can modulate cascades of genes in their activity . The search for developmental relevant genes identified the new ... -
Funktionsanalyse des Irx1-Gens
(2001-07-27)In D. melanogaster genes are composing a network, which determine neural cell lineage. Among them the genes of the Iroquois complex (IRO-C) are playing a crucial role in regulating the ... -
Funtional Analysis of the Murine Genes, MOCS1 and Sox15
(2003-08-06)In this work, function of the murine genes, MOCS1 and Sox15 were investigated. Human molybdenum cofactor deficiency is a rare and devastating autosomal-recessive disease for which no therapy ... -
Gene expression pattern and functional analysis of CD8+ T cells from individuals with or without anti HIV/SIV noncytolytic activity.
(2012-07-19)CD8+ T cell mediated antiviral response (CNAR) is associated with long-term control of HIV-infection and attributed to the secretion of an unknown factor called soluble CD8+ cell antiviral factor (CAF). In order to identify ... -
Generation of Endoplasmic Reticulum Protein 28 (ERp28) Knock Out Mice, and Structural and Functional Analysis of its Drosophila Homologue, Wind
(2004-02-16)My thesis work includes two parts: firstly, generation of a knock out mouse of a gene, ERp28, which encodes a putative endoplasmic reticulum chaperone protein and secondly, the structural ... -
Generation of Novel Photochromic GFPs: Fluorescent Probes for RESOLFT-type Microscopy at Low Light Intensities
(2012-05-23)The resolution of a conventional light microscope is limited by diffraction. Hence, light microscopy failed to discern objects that are closer together than half the wavelength of light. STED (STimulated Emission ... -
Genetic analysis of stoned B/stonin 2 function in vivo
(2005-07-04)Clathrin-mediated endocytosis at presynaptic nerve terminals is a regulated process tightly coupled to the exocytotic fusion event that requires clathrin, dynamin, AP2 as well as synaptotagmin ... -
Genetic and functional characterisation of killer cell immunoglobulin like receptors (KIR) of rhesus macaques (Macaca mulatta)
(2011-02-24)This PhD thesis reports the characterisation of the genetic diversity of killer cell immunoglobulin like receptors (KIR) as well as interactions between KIR and MHC class I molecules in the ... -
Genetic and Pharmacological Modulation of Alpha-Synuclein Aggregation
(2017-07-18)Several neurodegenerative disorders, such as Parkinson’s disease (PD), are characterized by the deposition of misfolded and aggregated forms of a particular protein in different areas of the brain. Understanding the molecular ... -
Genetic disruption of the master pacemaker in the suprachiasmatic nucleus sheds light on the hierarchical organization of the mammalian circadian timing system
(2011-11-30)Circadian timing systems evolved in most organisms to adapt to the daily alternation of light and dark and the accompanying changes of environmental parameters such as food availability and predator occurrence. Circadian ... -
Genetic Evidence For Neuron-Glia Metabolic Coupling In The CNS
(2016-07-27)The active contribution of oligodendrocytes and astrocytes to sustain brain physiology was completely underestimated, but severe consequences of their dysfunction in various diseases and glia-specific mutants emphasized ... -
Genetic factors driving the functional specification of spinal motor neurons
(2012-11-06)Spinal motor neurons which innervate different types of muscle fibers play a pivotal role in controlling body postures and locomotion. Spinal motor neurons can be broadly classified into alpha- and gamma-motor neuron ... -
Genetic fingerprints of microalgal culture strains: amplified fragment length polymorphism (AFLP) for investigations below the species level
(2006-05-16)The aim of the present thesis was to analyse microalgal culture strains at the level below species. This was important to improve the abilities of service culture collections of algae to ... -
Genetic variants of EPO and EPOR influence cognitive core features of schizophrenia
(2011-03-18)Introduction: Erythropoietin (Epo), a hematopoietic growth factor, has long been observed to improve cognition but this effect was attributed to the increase in hemoglobin levels. Even after ... -
Genetische Diversität in der Lichtensteinhöhle – Ableitungen zur Demographie und Interpretationen zu sozialen Strukturen sowie Bestattungssitten in einer bronzezeitlichen Bevölkerung
(2022-03-03)The archaeological part of the Lichtenstein Cave, a gypsum karst cave in the southwestern periphery of the Harz Mountains, was discovered in 1980 and has since been investigated in close, interdisciplinary cooperation. The ... -
Genetische Variabilität in der phagozytären NAD(P)H-Oxidase: Funktionelle Charakterisierung und Bedeutung für die Zytostatika-Therapie
(2010-01-05)Cardiotoxicity is a severe side effect of doxorubicin-containing chemotherapy as used in the treatment of several tumors and leukemia and up to 6% of treated patients develop congestive ...