Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Title
Now showing items 693-712 of 1652
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HORMA domain proteins in Autophagy initiation
(2022-08-01)The autophagic pathway is an evolutionarily conserved strategy among eukaryotic cells for maintaining cell homeostasis at the basal level and during stressful conditions. It removes protein aggregates, damaged organelles, ... -
Human and mouse meniscus progenitor cells and their role in meniscus tissue regeneration
(2014-05-19)Osteoarthritis (OA) is a degenerative disease of hyaline cartilage. The cartilage is an avascular tissue, once damaged it is difficult to repair. Articular cartilage is responsible for the smooth, frictionless, and painless ... -
Hydraulic traits and their relevance for water use strategies in five broad-leaved tree species of a temperate mixed forest
(2013-11-14)Without anthropogenic intervention, Central Europe would be covered by about 65% by beech-dominated broad-leaved forests. However, large forest areas have been replaced by coniferous monocultures since the early 19th century ... -
I. Etablierung eines induzierbaren Suizidsystems zur Identifizierung von Mutanten der salizylsäureabhängigen Signaltransduktion II. Expression von tierischen Signaltransduktionskomponenten in Tabak zur Herstellung eines induzierbaren Expressionssystems
(2002-09-04)During pathogen defense in plants the salicylic acid concentration increases. In response to this signal a number of defense genes is activated via a signal transduction chain few steps of ... -
Identification and analysis of novel insect head patterning genes
(2015-09-24)The insect head is a composite structure of several segments and an anterior non-segmental region. Due to head involution, the Drosophila larval head is strongly reduced and for technical reasons the developmental basis ... -
Identification and characterization of Campylobacter jejuni factors relevant for the infection process
(2007-10-09)Campylobacter jejuni is the most frequent bacterial cause of foodborne-illness in the developed world including Germany, where the reported number is 60,000 cases in a year. Despite the ... -
Identification and Characterization of Deafness Genes in Drosophila melanogaster
(2011-02-08)The antennal auditory organ of Drosophila, Johnston s organ (JO), provides a valuable system to study hearing. JO neurons and hair cells of mammals are developmentally specified via homologous ... -
Identification and Characterization of Microbial Key Functions in Soils of the German Biodiversity Exploratories Representing Different Land Use and Management Types
(2012-05-11)Soil probably harbors the highest microbial species diversity of any environment on Earth and represents a major reservoir of microbial taxonomic, genomic, and metabolic diversity. The most promising approach to gain ... -
Identification and Characterization of Novel Genes involved in Quinone Synthesis in the Odoriferous Defensive Stink Glands of the Red Flour Beetle, Tribolium castaneum
(2021-05-26)Defense strategies are common in insects including Coleoptera, the largest animal taxon containing various types of beetles. Stink gland secretion of beetles is playing an important role in their defense against detrimental ... -
Identification and Characterization of Protein Complexes Involved in Different Pain States in Vertebrates
(2019-02-28)Chronic pain imposes substantial challenges to medical practice as the treatment options for its clinically relevant manifestations are limited. Owing to lack of knowledge about the exact molecular mechanism underlying ... -
Identification and characterization of proteomic regulations in the cerebellum region of brain in MM1 and VV2 subtypes of sporadic Creutzfeldt-Jakob disease (sCJD)
(2017-05-17)Sporadic Creutzfeldt–Jakob disease (sCJD) is a fatal, transmissible spongiform encephalopathy (TSE) characterized by broad range of clinical and pathological manifestations. Pathological features of sCJD are largely dependent ... -
Identification and characterization of small molecule inhibitors of pre-mRNA splicing that block spliceosome assembly at novel stages
(2016-02-19)The spliceosome is a highly dynamic, megadalton ribonucleoprotein (RNP) molecular machine that catalyses the important step of the post-transcriptional processing of eukaryotic precursor messenger RNA (pre-mRNA), called ... -
Identification and characterization of virulence associated factors of C. jejuni
(2010-11-25)Campylobacter jejuni, an important food-borne human bacterial pathogen in industrialized countries and in the developing world, the leading cause of bacterial diarrhoea. The infection may ... -
Identification and Functional Characterization of Novel Genes Involved in Primary Neurogenesis in Xenopus laevis
(2002-07-16)The South African claw-toed frog, Xenopus laevis, is a good model to study neurogenesis in vertebrates. Early on, at the open neural plate stage, the territory of primary neurons is nicely ... -
Identification and Functional Characterization of Trans-acting Factors Involved in Vegetal mRNA Localization in Xenopus Oocytes
(2008-07-24)Directional transport of specific mRNAs is a mechanism for the generation of asymmetry which is of primary biological importance. In Xenopus oocytes, mRNA localization to the vegetal ... -
Identification and Functional Characterization of unc5A during Neocortical Regionalization
(2008-04-15)During the evolution of mammalian species, the cerebral neocortex acquired improved sensory, learning, and decision-making activities in parallel to its structural regionalization for specific functions. Each of these ... -
Identification of a new factor essential for vacuolar aminopeptidase I activity.
(2004-12-08)The Saccharomyces cerevisiae vacuolar aminopeptidase I, Ape1p, is transported from the cytoplasm to the vacuole by constitutive autophagocytosis. Ape1p is synthesized as a proform with a ... -
Identification of Arabidopsis genes involved in differential interaction phenotype establishment by distinct Verticillium spp. and isolates
(2018-04-20)Verticillium longisporum induces developmental reprogramming of A. thaliana Col-0 leading to transdifferentiation of chloroplast-containing bundle sheath cells to functional xylem elements. Moreover, re-initiation of cambial ... -
Identification of Genes in the Dorsal Raphe Nucleus Regulated by Chronic Stress and Citalopram
(2006-06-16)It is known that stress, especially when it is chronic, can lead to mood disorders and changes in the serotonergic (5-HT) system, which most probably play a role in stress-induced ... -
Identification of interacting partners of mammalian target of rapamycin complex 1 (mTORC1) assembly in human lymphocytes
(2012-02-14)The mammalian target of rapamycin (mTOR) is an intracellular protein kinase that plays a key role in the control of cell growth, differentiation, cell survival, and cell proliferation. In ...