Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Title
Now showing items 800-819 of 1686
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Intramembrane signal transduction and cell envelope stress response in <i>Bacillus subtilis</i>
(2008-02-04)The bacterial cell envelope is the first and major line of defence against threats from the environment. It is an essential and vulnerable structure that gives the cell its shape and ... -
Investigating chemical crosslinking of protein-RNA complexes by mass spectrometry
(2022-08-12)RNA plays a quintessential role in cellular processes such as gene expression, transcription, RNA processing, and translation. Proteins carrying out those diverse functions are inherently flexible to accommodate dynamic ... -
Investigating myelination in human bioengineered neuronal organoids (BENOs)
(2024-05-21)Myelination is a critical process for the optimal functioning of both the central and peripheral nervous systems. It involves wrapping nerve fibers with a myelin sheath to ensure the swift transmission of electrical signals, ... -
Investigating the role of lipocalin-2 as a diagnostic indicator for nonalcoholic steatohepatitis in a fructose-induced rat fatty liver model: First experimental studies
(2013-12-17)The liver is the vital organ for fat and carbohydrate metabolism as well as detoxification and excretion of metabolites. Any functional impairment will thus affect the whole organism and is absolutely undesirable. Nonalcoholic ... -
Investigating the Role of ROMO1 in Mitochondrial Protein Import and Inner Membrane Morphology
(2018-10-18)Mitochondria are vital organelles that perform fundamental functions such as ATP synthesis and iron-sulfur cluster formation. More than 99% of the mitochondrial proteome is imported by dedicated translocation machineries. ... -
Investigation into gene regulatory networks governing the development and maintenance of the planarian reproductive system
(2024-03-20)Regulation of gene expression is a fundamental mechanism allowing the existence of complex living systems. This regulation takes shape in the form of hierarchical gene regulatory networks (GRNs), culminating in the binding ... -
Investigation of cytoplasmic long noncoding RNA in Saccharomyces cerevisiae
(2025-06-12)Research on lncRNAs has increased in the past, but little is known about their function. Recently, discoveries have given us insight into sense- and asRNA regulation in yeast. dsRNA is formed in the nucleus and shuttles ... -
Investigation of early endosomal sorting and budding
(2009-11-04)Early endosomes constitute a major sorting platform of eukaryotic cells. They receive endocytic carrier vesicles from the plasma membrane and trafficking vesicles from the Golgi complex and ... -
Investigation of glycolysis in Bacillus subtilis
(2010-05-19)Bacillus subtilis is a model organism for Gram-positive bacteria and object for biotechnological applications. The extensive investigation of this bacterium makes it one of the best studied ... -
Investigation of Interactions between Homeodomain Proteins and DNA
(2004-09-10)In this work spectroscopic and transient-kinetic methods were applied to investigate homeodomain-DNA interactions. The analysis of intrinsic fluorescence and circular dichroism spectra of ... -
Investigation of myelin membrane adhesion and compaction in the central nervous system
(2013-02-13)Myelin is a multi-layered membrane which enwraps the axons in peripheral (PNS) and central nervous system (CNS). The formation and assembly of this structure is a multi-step process that is regulated by a variety of ... -
Investigation of Protein - Protein Interactions in Clathrin-Mediated Membrane Transport
(2006-11-13)Ever since it was reported that synaptic vesicle (SV) retrieval follows two kinetic phases, the molecular mechanisms corresponding to these kinetic modes have been controversially discussed. ... -
Investigation of Protein-protein Interactions within the Human Spliceosomal U4/U6.U5 tri-snRNP Particle
(2005-08-08)Two-hybrid data allowed me to define the regions through which proteins 220K, 200K, and 116K interact with each other. These regions include the N terminal and C-terminal domains of protein ... -
Investigation of storage polysaccharide metabolism in lactic acid bacteria
(2011-10-21)Glycogen biosynthesis and its regulation have been investigated extensively in bacteria at the level of ADP-Glc synthesis. The enzyme ADP-glucose pyrophosphorylase (ATP: α-dglucose-1-phosphate ... -
Investigation of Structure and Function of Esco1 and Esco2 Acetyltransferases
(2018-12-04)Cohesin is a protein complex, whose core subunits are assembled into a ring-like structure encircling the DNA. In this manner, cohesin traps DNA molecules and plays key roles in expression, repair, and segregation of ... -
Investigation of the higher order structure of the spliceosomal RNA network
(2007-02-05)Majority of the genes of higher eukaryotes possess introns (internal non-coding sequences) which have to be excised via splicing to generate translatable mRNAs. Recognition and pairing of ... -
Investigation of the mitochondrial contact site and cristae organizing system and its role in cristae formation
(2020-10-27)Mitochondria are essential organelles in eukaryotic cells that feature a unique doublemembrane architecture. The mitochondrial inner membrane forms numerous invaginations, named cristae, which can adopt different shapes ... -
Investigation of the role of prolyl isomerase A in protein misfolding associated with neurodegenerative diseases
(2023-06-26)Misfolded proteins and disrupted homeostasis are key characteristics of neurodegenerative diseases. There is a strong association between intrinsically disordered proteins and pathogenic misfolding in neurodegenerative ... -
Investigation of the structure of spliceosomal complexes from the yeast S. cerevisiae
(2021-03-19)Nuclear pre-mRNA splicing is catalysed by the spliceosome, a multi-megadalton ribonucleoprotein (RNP) complex. It assembles de novo for each round of splicing on premRNA intron with stepwise binding of five small nuclear ... -
Investigation of TOMM20 Interactome in Relation to Protein Quality Control and Translocation
(2024-11-11)The human mitochondria are home to a vast repertoire of approximately 1,500 proteins, most of which are synthesized within the cytosol and post-translationally translocated into the mitochondria. Amidst the intricate ...