Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Title
Now showing items 999-1018 of 1725
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Molecular mechanisms underlying silent synapse generation and their role in drug-associated behaviors
(2025-08-29)Silent synapses are immature glutamatergic connections that express stable NMDARs, while AMPARs are absent. These synapses are abundant during early development and serve as plasticity substrates, offering synaptic ... -
Molecular motions at the 5 stem-loop of U4 snRNA: Implications for U4/U6 snRNP assembly
(2005-07-05)The human 15.5K protein binds to the 5' stem-loop of U4 snRNA (KtU4), promotes the assembly of the spliceosomal U4/U6 snRNP, and is required for the recruitment of the 61K protein and ... -
Molecular phylogeny and morphological reconstructions of Plagiochilaceae (Jungermanniopsida) with hypotheses on biogeography and divergence times
(2006-10-30)Plagiochilaceae are one of the largest families of leafy liverworts, with an estimated species number of about 500, the magnitude of them placed in the genus Plagiochila. Members of the ... -
Molecular physiology of the inner hair cell ribbon synapses
(2005-08-05)During this work we investigated organization, molecular composition and function of hair cell ribbon synapses. We demonstrated RIBEYE, Bassoon and Piccolo to be components of IHC synaptic ... -
Molecular Physiology of the Ribbon Synapse
(2010-07-16)Hearing relies on Ca2+ influx-triggered exocytosis in cochlear inner hair cells (IHCs). In this study, we examined the regulation of IHC Ca2+ channels by the CaV(beta)2 Ca2+ channel subunit ... -
Molecular role of Pelota (PELO) in differentiation of embryonic and germ stem cells
(2015-11-05)Pelota (Pelo) is an evolutionary conserved gene, which has been characterized in diverse species. In mouse, Pelo deficiency results in embryonic lethality at early post-implantation stage. The in vitro culture of Pelo-null ... -
Molecular role of PMP22 in CMT1A
(2021-07-02)Myelinating Schwann cells wrap around peripheral axons and allow fast neural transmission. Peripheral myelin protein of 22 kDa (PMP22) is a transmembrane protein strongly expressed in Schwann cells. Alterations in PMP22 ... -
Molecular Studies on Head Development of the Amphipod Crustacean Parhyale hawaiensis
(2011-08-09)The adult head of bilateral-symmetric animals is an anterior, usually tagmatised morphological unit. In segmented phyla, the development of the anterior head segments underlies different ... -
Molekular-Dynamik-Simulationen zum Katalysemechanismus der Acetylcholinesterase
(2002-02-14)Acetylcholinesterase plays an important role in the signal transmission in cholinergic synapses. The aim of this work is to obtain a better insight into the catalytic reaction mechanism ... -
Molekularanthropologische Untersuchungen zur präkolumbischen Besiedlungsgeschichte des südlichen Perus am Beispiel der Palpa-Region
(2008-08-27)One of the elementary questions of the cultural sciences is whether and in which dimension cultural change is due to, or accompanied by population-biological change. This question is not ... -
Molekularbiologische Charakterisierung und vergleichende Genomik von ausgewählten Vertretern mariner Roseobacter-Stämme
(2014-03-13)The genome analyses presented in this thesis extend the current knowledge of the genomic potential of the Roseobacter clade and identify potential adaptations to ecological niches within marine habitats. New features were ... -
Molekularbiologische und biochemische Untersuchungen zum bakteriellen Naturkautschuk-Abbau, sowie Charakterisierung eines dazu befähigten Bakteriums
(2001-06-29)As a natural product, natural rubber (cis-1,4-polyisoprene) is subjected to a continuous biological process of degradation in the biosphere. For this reason it is astonishing that the exact ... -
Molekularbiologische und Röntgenmikroskopische Charakterisierung der Heterochromatinproteine des Nematoden Caenorhabditis elegans
(2001-12-12)The nematode C. elegans was the first multicellular organisms whose genome was completely sequenced (The C. elegans Sequencing Consortium, 1998). This model organism is highly eligible for ... -
Molekularbiologische Untersuchungen zu zentralnervösen Alterungsprozessen der Reproduktionsfunktion in der weiblichen Ratte
(2003-01-08)GABA neurones, as part of the GnRH network, play a significant role in the changes of age-related processes of the reproduction function. In order to study the regulation of the ovarian ... -
Molekulare Analyse der differentiellen Funktionen von Linkerhiston Isoformen bei Caenorhabditis elegans.
(2002-01-29)Linker histones are non-essential for the life on single-celled eucaryotes. Linker histones, however, can be important components of specific developmental programs in multicellular animals ... -
Molekulare Analyse des Biotin-regulatorischen Netzwerks Sinorhizobium meliloti durch Proteomanalyse, Expressionsstudien und Mutagenesen
(2003-10-16)Sinorhizobium meliloti is not able to synthesize endogenous biotin. Biotin-limitation leads to a clear reduction of metabolic activities, whereas biotin-sufficiency has a positive ... -
Molekulare Mechanismen der Regulation der Glukagon-Gentranskription durch die Pax6-Homöodomäne
(2007-06-05)The peptide hormone glucagon increases glucose output from the liver and thus maintains sufficient blood glucose levels during the fasting state. Malfunctions in biosynthesis and secretion ... -
Molekulare und funktionelle Analyse des Gens rings lost (CG4420) in der Entwicklung von Drosophila melanogaster
(2010-05-17)Oogenesis of Drosophila is an attractive model system to study the arrangement of the actin-cytoskeleton. At the beginning of oogenesis a 16-cell cyst is formed and all cells of these cyst ... -
Molekulare und funktionelle Analyse von Windei (CG12340) als Bindungspartner der Histonmethyltransferase Eggless während der Oogenese von <i>Drosophila</i>
(2009-02-16)The epigenetic regulation of gene expression plays a very important role in development and is often mediated by the methylation of histones. Trimethylation of histone 3 lysine 9 (H3K9me3) ... -
Molekulare, biochemische und strukturelle Untersuchungen an amylolytischen Enzymen von Thermotoga maritima MSB8
(2001-08-01)One of the most thermophilic and ancient bacteria known to date, the hyperthermophilic Thermotoga maritima MSB8 (growth range: 55°C - 90°C), degrades and fermentatively utilizes organic ...