Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Issue Date
Now showing items 21-40 of 1658
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An automated data integration platform for interpreting genomic data and reporting treatment options in molecular tumor boards
(2024-08-16)This thesis presents significant advancements in precision oncology, focusing on enhancing MTB workflows through the development and integration of innovative bioinformatics tools and methodologies. These contributions ... -
Cognitive Foundations of Ascribing Intentional Action
(2024-08-09)Understanding and interpreting actions is fundamental for profoundly social beings like humans. We explain and predict intentional actions of others by reference to mental states, such as beliefs, desires and intentions. ... -
Influence of clock gene homologs and Pseudomonas spp. on Verticillium dahliae development and host plant interaction
(2024-08-09)The soil-borne phytopathogenic fungus Verticillium dahliae requires a tight regulation to form different developmental structures for infection, colonization of the plant vasculature and survival in soil. The fungal life ... -
Characterization of the Phosphomimetic Mutant Y39E of a-Synuclein
(2024-08-06)α-Synuclein (aSyn) has long been identified as a key factor in the pathogenesis of Parkinson's Disease (PD), with familial mutations in the SNCA gene contributing to the aberrant aggregation of aSyn. Its aggregation results ... -
Mobile Cognitive Interventions in Mental Disorders
(2024-08-05)Mental disorders pose a significant public health challenge, contributing substantially to disability-adjusted life years and increasing mortality rates. Despite their prevalence, the mechanisms underlying the development, ... -
Trophic ecology of earthworms: the relative role of litter- and root-derived resources investigated with compound-specific stable isotope analysis of amino acids
(2024-07-23)Earthworms, known as ecosystem engineers, shape the structure and functioning of ecosystems by altering nutrient cycling, habitat architecture and plant growth due to feeding interactions or physiological activities. They ... -
The Role of Low-Level Visual Features in the Emotional and Motivational Relevance of Symbolic Stimuli
(2024-07-16)In our daily lives, we encounter a wide range of visual stimuli, but printed words are critical for communication and information acquisition. Emotional words receive preferential attention, resulting in modulations of ... -
The role of Wnt signalling in the microtubule-mediated maintenance of chromosomal stability
(2024-07-05)Chromosomal instability (CIN) is a major hallmark of cancer and represents a driving force for tumourigenesis, tumour progression, and the development of therapy resistance. CIN can be subdivided into structural CIN ... -
Analysis of the Antiviral Restriction Factor Shiftless in the context of HIV-1 Programmed –1 Ribosomal Frameshifting
(2024-07-05)The human immunodeficiency virus 1 (HIV 1) is responsible for a major global health crisis, the acquired immunodeficiency syndrome (AIDS) pandemic. Retroviruses integrate their genetic material into the genome of host ... -
Untersuchung von risikoprognostisch relevanten Faktoren und Aufmerksamkeitsprozessen bei Personen mit normativem und deviantem sexuellen Interesse
(2024-06-28)Child sexual abuse is associated with far-reaching negative consequences for its victims. With the increasing spread of the internet in recent decades, this no longer takes place exclusively through direct contact, but ... -
NMR spectroscopy of liquid-liquid phase separation related to transcription
(2024-06-05)The Carboxyl-Terminal Domain (CTD) of the largest subunit RPB1 of RNA Polymerase II (Pol II), is a disordered low-complexity region which is crucial for pre-mRNA transcription and processing. Due to its highly repetitive, ... -
Population Trends of Common Breeding Birds in Germany: Patterns, Drivers, and Conservation Implications
(2024-06-05)Biodiversity is declining globally. To detect population declines early, biodiversity monitoring is crucial. It enables scientists to prioritize research into the causes of declines, investigate drivers of population change, ... -
Analyzing host shift patterns of Wolbachia (Alphaproteobacteria) among arthropods using comparative genomics
(2024-05-28)In this thesis, I investigated the host shift event and patterns of the endosymbiotic bacterium Wolbachia. I examined the molecular diversity and distribution of Wolbachia among arthropod communities of different terrestrial ... -
Investigating myelination in human bioengineered neuronal organoids (BENOs)
(2024-05-21)Myelination is a critical process for the optimal functioning of both the central and peripheral nervous systems. It involves wrapping nerve fibers with a myelin sheath to ensure the swift transmission of electrical signals, ... -
Role of clathrin-mediated endocytosis in myelinating oligodendrocytes
(2024-05-17)The myelin sheath is a multi-layered oligodendroglial membrane that enwraps axons, providing insulation and support. Although myelin is one of the most long-lived structures in the nervous system, its maintenance requires ... -
Engagement in web-based interventions for individuals who sexually abused children
(2024-05-16)Although treatment for individuals who committed sexual offenses against children (ICSOC) can reduce their likelihood of reoffending, many individuals remain without treatment due to a lack of its availability. One way to ... -
Protein Signatures of Incision Injury in Humans and Mice - a Translational Study
(2024-05-08)Acute pain is the physiological reaction of a body to noxious external stimuli such as surgical interventions. Depending on the intensity and persistence of pain, tissue recovery may be hampered leading to post-operative ... -
Effects of climate change and land use on the structure and function of earthworm communities
(2024-05-07)Human activity-induced global change is increasingly threatening biodiversity and composition of species assemblages worldwide, which reduces ecosystem resilience and provokes concerns about ecosystem functions. Over the ... -
Macromolecules in Motion by High-resolution Cryo-EM
(2024-05-06)Protein synthesis, the translation of the genetic code into a defined sequence of amino acids, is a central, highly dynamic and regulated step in gene expression. The well-defined bacterial translation system enables to ... -
Causes and consequences of female competition in redfronted lemurs (Eulemur rufifrons)
(2024-04-19)Competition among female mammals appears to be much more widespread than previously thought, and it can take on extreme forms, including eviction and even death. Nevertheless, female competition has only recently been ...