Alzheimer s disease (AD) is a progressive neurodegenerative disorder, characterized by early deficits in learning and memory with eventual loss of higher cognitive functions. Although ...

While developmental processes have been extensively studied in the context of transcriptional regulation, much less is known about regulation via translational regulation. RNA-binding ...

Restless legs syndrome (RLS) comprises of both sensory and motor symptoms, observed as an increased pain and periodic jerking movement of the legs. There are two forms of RLS; one ...

Nearly 60% of patients infected with HIV are affected by neurological and psychiatric symptoms. The motor and cognitive dysfunctions, as well as behavioral changes are described by the term ...

Crustaceans have frequently been used to study the neuroethology of diverse function as agonistic behavior and circadian rhythms. Whether the highly stereotyped and quantifiable agonistic ...

This thesis focuses on the structure and function of rhesus macaque (Macaca mulatta, Mamu) major histocompatibility complex (MHC) class I genes. As the cellular immune response is at least ...

The formation of new tumor vessels (tumorangiogenesis) is an important mechanism for the growth and progression of tumors. Tumorangiogenesis depends on a complex interplay between pro-and ...

Nuclear eukaryotic DNA is organised as chromatin in conjunction with proteins. The basal structural organisation unit of chromatin is the nucleosome consisting of the nucleosome core particle, ...

Human defensins are natural peptide antibiotics. On the basis of the position and bonding of their six highly conserved cysteine residues, they are divided into two families, designated alpha- und beta-defensins. ...

In the present work, we investigated Bcl-2-associated athanogene-1 (BAG1) as a therapeutic molecule in the lesioned visual system in vivo. The effects of BAG1 were tested in two in vivo models of apoptosis and regeneration, ...