Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Advisor "Günesdogan, Ufuk Dr."
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Computational analysis of transcriptional regulation and chromatin assembly
(2023-12-07)Primordial germ cells (PGCs), the precursors of gametes, are specified from post-implantation epiblast cells in response to bone morphogenetic protein (BMP) signaling at the onset of gastrulation in mouse. Followed by ... -
Understanding the role of the transcription factor MGA in primordial germ cell differentiation
(2023-06-20)One of the most crucial cell lineage decisions in mammalian embryos is the differentiation of a few pluripotent epiblast cells into primordial germ cells (PGCs). PGCs are unique for their ability to mature into either sperm ... -
Understanding Transcriptional Control During Primordial Germ Cell Differentiation
(2022-07-08)AP2γ, encoded by Tfap2c, is a transcription factor which both represses and activates target gene expression. It is required for the survival of the early mouse embryo; depending on the context of its depletion, the loss ...