Dokumente Fakultät für Biologie und Psychologie (inkl. GAUSS) nach Gutachter "Boretius, Susann Prof. Dr."
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Ablation of cell-specific cholesterol synthesis affects cerebral β-amyloidosis
(2023-03-13)Cholesterol, an essential membrane component, among others modifies membrane fluidity and regulates cell signaling. CNS cholesterol metabolism is separated from peripheral cholesterol by specific properties of the ... -
Anti-apoptotic and neuroprotective erythropoietin/CRLF3-signalling in insects and humans
(2022-06-14)The cytokine receptor like factor 3 (CRLF3) evolved together with the eumetazoan nervous system and is present in all major groups of Animalia. Based on sequence similarities, CRLF3 was assigned to the family of class 1 ... -
CMTM5 - a novel CNS myelin protein involved in preserving axonal integrity
(2022-04-28)Myelination of axons in the nervous system facilitates rapid, saltatory signal propagation, accelerating nerve conduction speed manyfold. Additionally, myelinating glia support the long-term integrity of axons they ... -
Functional imaging of the anesthetized brain in primates and rodents
(2022-07-05)Understanding the brain is aided by visualizing neural activity over time. The most popular method for doing so in humans is functional magnetic resonance imaging (fMRI)—a method that tracks blood oxygenation as a proxy ... -
Metabolic alterations in Charcot-Marie-Tooth disease type 1A
(2021-05-03)Axo-glia interaction extend beyond myelination itself. Glial cells support axons with metabolites and trophic factors. In numerous disease models, primary glial mutations result in the disturbance of normal nerve conduction. ... -
The manifestations and interdependence of social and physiological aging in wild female Assamese macaques (Macaca assamensis)
(2023-12-11)Aging is a multifaceted process which increases the probability of death, and although there can be only one outcome, the ways to get there are diverse. Accumulating evidence of aging in natural animal populations has shed ...