Dokumente Fakultät für Biologie und Psychologie (inkl. GAUSS) nach Gutachter "Bucher, Gregor Prof. Dr."
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Analysis of Tribolium head patterning by forward and reverse genetics and transgenic techniques
(2009-09-09)In this thesis several different methods have been applied to get deeper insights into the complex process of head development in insects. As model organism the red flour beetle Tribolium ... -
Analyzing the molecular mechanism of Bucky ball localization during germ cell specification in zebrafish
(2015-08-19)Sexual reproducing animals depend on the proper establishment of the germline to ensure the survival of the species by generating fertile progeny. Therefore, many vertebrate and invertebrate species specify their ... -
Anti-apoptotic and neuroprotective erythropoietin/CRLF3-signalling in insects and humans
(2022-06-14)The cytokine receptor like factor 3 (CRLF3) evolved together with the eumetazoan nervous system and is present in all major groups of Animalia. Based on sequence similarities, CRLF3 was assigned to the family of class 1 ... -
Application of RNA Interference for the Study of Lethal Genes and Dynamic Processes
(2016-02-08)RNA interference (RNAi) is a highly conserved cellular mechanism and in the last years it has become to a major tool for functional analyses of genes in different species. Moreover, RNAi has recently been suggested as a ... -
Behavioual Adaptations to Light Deprivation
(2019-03-20)Similar to most non-sedentary animals, Drosophila shows a wide range of visually guided behaviours and their functionality is crucial for survival. Previous studies showed that visual impairment significantly reduced the ... -
Biotechnological approaches to fight fruit flies of agricultural importance
(2012-10-08)Tephritid fruit flies destroy fruits and vegetables, causing tremendous economic losses and bringing a barrier to trade in fruits, vegetables and their associated products. The Sterile Insect Technique (SIT), a target-specific ... -
Characterization of proneural bHLH transcription factor target genes in X. laevis
(2022-09-23)Zc3h12c is a member of the Zc3h12 endoribonuclease family (also known as MCPIP/Regnase), which contains four members (Zc3h12a-c). This family of proteins is characterized by the presence of a single centrally located ... -
Characterization of the neuronal proteolipids M6A and M6B and the oligodendroglial tetraspans PLP and TSPAN2 in neural cell process formation
(2012-07-12)The tetraspan-transmembrane proteins of the M6-proteolipid proteolipid protein family are among the most abundant cell surface proteins in neurons. Their cellular function has remained largely speculative, also because ... -
Charakterisierung von lipid droplet-Regulatoren der Fruchtfliege <i>Drosophila melanogaster</i>
(2012-09-28)The storage of lipids as a reservoir for energy and biosynthetic building blocks is a central feature of life. At the same time, storage amounts need to be tightly controlled since a failed regulation severely impacts the ... -
Comparative studies on the role of Egfr, Wingless and Decapentaplegic signalling in leg development in the red flour beetle Tribolium castaneum
(2012-04-18)Leg development and its underlying genetic and molececular mechanisms are best understood in the prime insect model Drosophila melanogaster and this knowledge can serve as a first guide to study leg development in other ... -
Cortical patterning in syncytial embryos: the link between microtubules and actin cortex
(2020-01-20)Abstract Spatial and temporal regulation of cortical proteins on the cell membrane leads to cortical polarization of cells. After cortical polarization, the cell membrane can divide into different domains such as apical ... -
Development of a biotechnologically enhanced sterile insect technique to fight coleopteran pests
(2021-06-30)Tribolium castaneum commonly referred to as the Red Flour Beetle (RFB) belongs to the class Insecta and order Coleoptera, and it’s the best model organism for coleopterans. About 380,000 coleopteran species, constituting ... -
Development of Transgenic Sterile Insect Technique Strains for the Invasive Fruit Pest Drosophila suzukii
(2020-12-03)Globalization has contributed enormously to emergence and expansion of invasive pests. A recent example is the invasion in Europe and the USA by the cherry vinegar fly Drosophila suzukii. The pest has high potential to ... -
Evolution of caudal translational repression in higher insects
(2011-03-03)The anterior patterning factor bicoid (bcd) mediates translational repression of caudal (cad) in Drosophila embryos and is an evolutionary novelty present only in higher dipterans. ... -
Evolution of Sp Transcription Factors in Metazoans
(2010-02-09)In contrast to the well-known trunk segmentation mechanisms in the fruit fly Drosophila melanogaster the mechanisms of arthropod head segmentation are less well understood. While the ... -
Exploring morphological innovation and diversification: Analysis of genes involved in gin-trap formation and antenna remodeling during metamorphosis in Tribolium castaneum
(2017-08-18)How morphological traits originate and diversify is a central question in evolutionary biology. Insects are the most diverse group of animals on the planet and over 80% of insect species belong to the subgroup of holometabola. ... -
Formation of the Clypeolabral Region During Embryonic Head Development of the Red Flour Beetle Tribolium castaneum
(2012-07-26)Insects are segmented organisms but the number of segments contributing to the head is disputed. The most anterior head region is patterned differently from the rest of the body and, therefore, is considered to be ... -
Functional analysis of embryonic brain development in Tribolium castaneum
(2011-08-31)The brain is one of the most complex organs in animals. It allows the coordination of complex operations like orientation and directed movements. In insects, a structure in the brain has ... -
Functional characterization and molecular identification of neuroprotective receptors for erythropoietin-like ligands
(2019-12-19)The cytokine erythropoietin (Epo) regulates erythropoiesis but also protects mammalian neurons from apoptosis. However, receptors and transduction pathways involved in neuroprotection are only partially characterized. ... -
Funktion und Evolution von hochkonservierten Kopfgenen im Reismehlkäfer Tribolium castaneum
(2009-09-09)The anterior-posterior axis of all bilaterian animals is subdivided into a posterior region marked by the expression of highly conserved Hox-cluster genes and an anterior region free of ...