Browsing Fakultät für Biologie und Psychologie (inkl. GAUSS) by Referee "Gradmann, Dietrich Prof. Dr."
Now showing items 1-20 of 24
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5HT 2 Rezeptor vermittelte Kontrolle des neonatalen medullären respiratorischen Netzwerks des Säugers
(2002-10-18)The serotonin 2B receptor (5HT 2B receptor) is an important regulator of embryonic development. Inactivation of the 5HT 2B gene leads to embryonic and early neonatal death in mice (Nebigil ... -
Characterisation of Vti1b and Vti1a proteins and generation of knock-out mice.
(2002-07-09)Genomic DNA for Vti1b and Vti1a was isolated and the chromosomal regions characterised. Using targeted gene disruption mouse mutants lacking Vti1b constitutively were generated. It was shown ... -
CHARACTERIZATION OF BACTERIAL LIPOPOLYSACCHARIDES (Pseudomonas syringae pv. tomato and Pseudomonas syringae pv. apii) AND PECTINS OF TOMATO AND CELERY PLANTS (Lycopersicon esculentum and Apium graveolens) REGARDING THEIR POSSIBLE ROLE IN HOST/PATHOGEN-INTERACTION
(2002-10-15)All plants face a formidable challenge of defending themselves against a large number of pathogens. The interactions between a pathogen and its host are governed by a number of factors. ... -
Characterization of the 5-HT7(a) receptor: Specific receptor - G- protein interactions
(2004-08-31)Serotonin (5-hydroxytryptamine, or 5-HT) is very important neurotransmitter which regulates a variety of different physiological processes within the central Nervous System and at the ... -
Charakterisierung eines neuen Proteins, Mapl-1 und seine Rolle in der Regulation der Pax-6 Funktion.
(2002-01-22)Pax proteins comprise a family of highly conserved transcriptional regulators that hold essential roles during embryonic development and organogenesis. The structural motif common to all ... -
Chlorellavirus-Proteine: I. Die Hüllprotein-Genfamilie II. Ein primitiver Kaliumkanal
(2000-11-07)Part I: The coat protein gene family Coat proteins play a decisive role in viral host recognition. They interact specifically with structures of the cell surface and mediate viral adherence. ... -
Differentielle Genexpressionsanalyse aktivierter Endothelzellen
(2001-08-28)Differential Display-PCR (DD) is a mRNA-fingerprint technique to identify differentially expressed genes by comparing displayed sets of randomized amplified cDNA. For this, an elaborated ... -
Exposition von Proteinen auf der Oberfläche von Escherichia coli Zellen: mechanistische Betrachtung und biotechnologische Anwendung
(2003-12-10)Methods of molecular evolution play an important role for the optimization of biomolecules with respect to function, stability, or interaction. A key aspect is the generation of protein ... -
Gezielte Modifikation sowie Analyse der Bindungseigenschaften des Histidin Bindeproteins aus Escherichia coli und des GCN4 Leucinzippers aus Saccharomyces cerevisiae
(2002-11-27)The histidine-binding protein (HisJ) belongs to the super-family of soluble periplasmic receptor proteins in gram-negative bacteria like Escherichia coli. HisJ takes part in transloctation ... -
Identifizierung der für die Agonisten-induzierte Phosphorylierung und Internalisierung relevanten Serine und Threonine in der C-terminalen Domäne des humanen Prostaglandin E2 Rezeptors, Subtyp EP4
(2003-08-18)The prostanoid receptors belong to the family of G protein-coupled receptors with seven transmembrane domains. Four different subtypes have been identified for prostaglandin E2 (PGE2). The ... -
Kartierung von umhüllungsrelevanten Aminosäureresten auf dem Hepatitis B Virus Kapsid
(2004-07-30)During morphogenesis of the hepatitits B virus (HBV) the cytosolic build nucleocapsid containing the viral genome interacts with transmembrane viral surface proteins to get enveloped into ... -
Molecular mechanisms governing germ line development in zebrafish and the role of this lineage in sexual differentiation
(2006-03-17)Primordial germ cells (PGCs) in zebrafish are specified early in the development by inheritance of a specific type of cytoplasm termed germ plasm. The asymmetrically distributed germ plasm ... -
Neuroligin: Charakterisierung eines neuronalen Transmembranproteins
(2004-02-06)Synapses are highly specialized contact sites where the communication between nerve cells takes place. Cell adhesion proteins are the key regulators of synaptogenesis and modulation. The ... -
Post-translational generation of Cá-formylglycine in Prokaryotic Sulfatsases by Radical SAM-Proteins
(2004-02-16)Cá-formylglycine is the catalytic residue of sulfatases. FGly is generated by posttranslational modification of a cysteine (pro- and eukaryotes) or serine (prokaryotes) located in a conserved ... -
Recognition of basic sorting motifs within synaptic membrane cargo proteins by the clathrin-adaptor complex AP-2
(2005-08-24)Communication in the central nervous system (CNS) occurs via chemical synapses, intercellular asymmetric junctions between an axon and the dendrite of a neighbouring neuron. Synapses comprised ... -
Repression der cytosolischen GS1 von Zuckerrüben (Beta vulgaris L. var. altissima) durch Antisense-DNA-Konstrukte
(2001-06-06)The accumulation of the main storage amino acid glutamine in sugar beet (Beta vulgaris L. cv. altissima) affects the sugar production. In order to reduce the amount of glutamine in sugar ... -
Role of transport systems in cortisol release from human adrenal cells
(2004-05-25)Adrenal steroid hormones (e.g., cortisol) play a pivotal role in the regulation and maintenance of metabolic homeostasis. The secretion of glucocorticoids from adrenocortical cells into ... -
Studies on the control and function of chromatin fragmentation during apoptosis
(2005-08-10)Apoptosis in eukaryotic cells is often accompanied by chromatin cleavage resulting in nucleosomal fragments. This cleavage is catalyzed by a DNase (named DFF40 or CAD) which is specifically ... -
The regulation of hypoxia-responsive gene expression by hydroxyl radicals and intracellular calcium
(2004-02-27)The heterogeneous oxygen distribution in tissues requires an oxygen-sensing system and a subsequent signaling pathway to allow the execution of adaptive responses. It has been proposed that ... -
The Regulatory Role of Syntaxin 1 N-terminal Conformation in Vesicle Priming and Exocytosis
(2004-12-16)During vesicle priming at the central synapse, Syntaxin 1, together with SNAP25 and Synaptobrevin, assemble into the synaptic SNARE complex. The formation of SNARE complex is thought to ...