Dokumente Fakultät für Biologie und Psychologie (inkl. GAUSS) nach Gutachter "Hoppert, Michael PD Dr."
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Analyse der UPR vermittelten Stressantwort und ihrer Funktion während der biotrophen Entwicklung von<i> Ustilago maydis</i>
(2016-12-09)The unfolded protein response (UPR) is a conserved eukaryotic signaling network that is activated by accumulation of misfolded proteins in the endoplasmic reticulum (ER) to ensure protein homeostasis. In the baker's yeast ... -
Analyse des Vorkommens, der Morphologie und der genetischen Diversität von Biologischen Bodenkrusten extrazonaler Gebirgssteppenstandorte der nördlichen Mongolei
(2011-08-18)At extrazonal mountain steppe sites in the western Khentej in Northern Mongolia there was to be explored the appearance, the morphology and the genetic diversity of Biological Soil Crusts. ... -
Assessment of antibiotic resistance in soil and its link to different land use types and intensities
(2020-07-15)Nowadays, bacterial infections pose a serious risk for human health again, due to multi-resistant pathogens insensitive to antibiotic treatment. Some of the antibiotic resistance genes (ARGs) carried by these pathogens ... -
Assessment of the functional diversity of soil microbial communities in the German Biodiversity Exploratories by metagenomics
(2011-04-18)Soil is the most complex microbial habitat on Earth with respect to bacterial species diversity and community size. Therefore, assessing the bacterial community composition in soil is a ... -
Biochemische, molekularbiologische und genetische Untersuchungen über strukturelle Voraussetzungen für DNA U-Endonukleaseaktivität in der ExoIII-Familie von DNA Reparaturenzymen
(2010-03-05)One of the most serious problems in any organism is the spontaneous hydrolytic DNA damage. The problem of U-DNA repair is being intensively studied in thermophilic and hyperthermophilic ... -
Biodiversity of terrestrial algal communities from soil and air-exposed substrates using a molecular approach
(2016-03-08)Terrestrial green microalgae are important primary producers in various habitats like soils, stone (epilithic and endolithic), tree bark and artificial hard substrates. In this thesis, the molecular diversity of green algae ... -
Bone Marrow Derived Adult Stem Cells: Characterization and Application in Cell Therapy
(2007-04-25)Due to their high plasticity, ES cells offer a great promise in regenerative medicine; however, the ethical and serious clinical problems limit their application. On the other hand, the ... -
Cardiac T-Tubule Membranes - Nanostructure and Remodeling Mechanisms in Disease
(2013-09-03)Transverse tubules (T-tubules, TTs) are continuous invaginations of the plasma membrane which form a complex network of excitable membranes inside mammalian ventricular cardiomyocytes. The TT network couples electrical ... -
Characterization of high-density prion protein oligomers in rapid progressive and sporadic Alzheimer’s disease
(2019-03-18)Alzheimer’s disease is the most commonly occurring dementia of the elderly, comprising up to 75% of all the neurodegenerative disorders. Over the past few decades, some atypical AD cases have been reported with a higher ... -
Chemosynthetische Endosymbiosen an rezenten und fossilen Cold Seep-Standorten
(2013-11-15)This thesis is focused on symbiosis between bivalves and autotrophic microorganisms (thiotrophic bacteria and phototrophic algae). The symbiotic relationship leads to special isotopic traces in the organics of the bivalves’ ... -
Dependence of soil microbial community structure and function on land use types and management regimes
(2016-11-10)Soil microbial communities are the most diverse assemblages of organisms on earth. They play key roles in nutrient cycling and help prevent soil erosion. Soil microbial communities also harbor many potentially plant-associated ... -
Discovery and Functional Characterization of Novel Soil-metagenome Derived Phosphatases
(2019-07-22)Phosphatases, including phytases, play a major role in phosphorous cycle, cell metabolism, biotechnology, and pathogenic processes. Despite their relevance as biocatalysts, the study of phosphatases/phytases has been almost ... -
Distribution and ecological characteristics of members of the Roseobacter group
(2020-08-27)Marine Rhodobacteraceae are collectively referred to as the Roseobacter group, and due to their functional versatility and high abundance in diverse marine habitats, serve as model organisms in the study of microbial ... -
Diversity and Activity of Soil Bacterial Communities under different Management Regimes
(2015-12-09)Bacteria are key players in nutrient cycles and energy transduction in soil. Although soil bacterial communities have been studied for several decades, our knowledge on their structure, dynamics ecosystem function is still ... -
Efficacy of enzyme replacement therapy in α-manosidosis mice
(2006-08-11)The Lysosomal Storage Disorders (LSD) are a group of about 50 diseases caused by genetic defects that affect one or more of the lysosomal hydrolases. The defect results in the accumulation ... -
Der Einfluss der Glutamatdehydrogenasen auf die Verknüpfung des Kohlenstoff- und Stickstoffstoffwechsels in Bacillus subtilis
(2011-06-01)Glutamate is the central amino group donor for all nitrogen containing compounds in the cell. In the Gram-positive soil-dwelling bacterium Bacillus subtilis glutamate is exclusively synthesized ... -
Evolutionary Genomics of Bacillus thuringiensis
(2017-11-07)Nowadays, many evolutionary processes and involved key factors are known but how they influence natural genetic variation and phenotypic traits in bacteria is under debate. However, the mechanism of evolution as well as ... -
Exploring the Functional Relevance of Polymorphisms within the CD14 and IRF-1 Gene for Promoter Activity by Haplotype-Specific Chromatin Immunoprecipitation (HaploChIP)
(2011-02-16)Genetic background may influence susceptibility and progression of various diseases. The IRF-1 promoter polymorphism rs2549009 (G/A) and the variant rs2569190 (C/T) within the CD14 gene ... -
Funktionelle Analyse RNA-basierter Regulation des zentralen Energiestoffwechsels in Bacillus licheniformis
(2015-12-17)This present dissertation focused on the identification, analysis and genetic manipulation of RNA-based regulators for strain optimization purposes. The source material of this work was transcriptome data from industrial ... -
Funktionelle Genomanalyse bakterieller Erreger, assoziiert mit der Europäischen Faulbrut von Honigbienen
(2015-11-23)Paenibacillus larvae and Melissococcus plutonius cause American foulbrood (AFB) and European foulbrood (EFB) on honey bees, respectively. Three typical strains of M. plutonius were isolated from a Swiss EFB outbreak. The ...