Dokumente Fakultät für Biologie und Psychologie (inkl. GAUSS) nach Gutachter "Söding, Johannes Dr."
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Alignment-free Phylogenetic Placement and its Applications
(2023-03-03)The study of the evolutionary interrelations of living organisms has been at the heart of biological sciences all along. A revolution in sequencing techniques in the past decades has caused a massive increase in molecular ... -
Computational methods for de novo assembly and sequencing error correction of short reads in the era of (viral) metagenomics
(2022-12-15)Viruses can affect all types of living cells, including bacteria, archaea and eukaryotes. Especially in the form of bacteriophages - bacteria infecting viruses - they have a huge impact on their host communities, driving ... -
Explaining decisions of graph convolutional neural networks for analyses of molecular subnetworks in cancer
(2022-05-03)Contemporary deep learning approaches exhibit state-of-the-art performance in various areas. In healthcare, the application of deep learning remains limited since deep learning methods are often considered as non-interpretable ... -
Investigation on the molecular factors driving the formation of distinct tau 'strains'
(2022-11-28)Pathological aggregation of the microtubule-binding protein tau into amyloid fibrils is a hallmark of different neurodegenerative diseases collectively termed tauopathies. To date, tau amyloid structures associated with ... -
Understanding the role of the transcription factor MGA in primordial germ cell differentiation
(2023-06-20)One of the most crucial cell lineage decisions in mammalian embryos is the differentiation of a few pluripotent epiblast cells into primordial germ cells (PGCs). PGCs are unique for their ability to mature into either sperm ...