Dokumente Fakultät für Biologie und Psychologie (inkl. GAUSS) nach Gutachter "Schmidt, Manuela Dr."
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Characterization of novel protein players in pain
(2023-08-16)Despite its high prevalence in the human society, the mechanisms underlying chronic pain and pain chronification are still poorly understood. The shortage of potential targets that are specific to pathological chronic pain, ... -
Characterization of protein complexes associated with TRP channels in the context of nociception
(2017-12-05)The transient receptor potential A1 (TRPA1) channel is essential for vertebrate pain. TRPA1 plays a fundamental role as a primary detector of noxious stimuli of physical and chemical nature, and is critically involved in ... -
Chromophore-independent roles of Drosophila opsin apoproteins and visual cycle components
(2019-02-13)Visual rhodopsins consist of opsin protein moieties that are covalently bound to 11-cis-retinal, the visual chromophore that is derived from vitamin A. In Drosophila, the visual opsin genes Rh5 and Rh6 were reported to be ... -
Identification and Characterization of Protein Complexes Involved in Different Pain States in Vertebrates
(2019-02-28)Chronic pain imposes substantial challenges to medical practice as the treatment options for its clinically relevant manifestations are limited. Owing to lack of knowledge about the exact molecular mechanism underlying ... -
Optogenetic Manipulation of the Auditory System
(2021-12-14)There are millions of people who are affected from sensorineural hearing loss. In this type of deafness, sensory hair cells are typically dysfunctional or lost, and thereby not conveying sound information to brain. The ...