Dokumente Fakultät für Biologie und Psychologie (inkl. GAUSS) nach Gutachter "Stülke, Jörg Prof. Dr."
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A method for the genetically encoded incorporation of FRET pairs into proteins
(2014-09-03)Proteins are composed of 20 canonical amino acids whose unique arrangements predefine a protein’s structure and function. Importantly, most proteins are not static conformations but rather very dynamic entities that undergo ... -
A novel rRNA quality control function for Npl3 in Saccharomyces cerevisiae
(2024-03-25)In all domains of life, ribosomes are essential complexes that are the sole source for protein synthesis. Ribosome biosynthesis, the most energy-consuming process in a cell, has to be tightly regulated. Misregulation ... -
An mRNA degradation complex in Bacillus subtilis
(2011-12-14)In every organism the degradation of mRNAs is a fundamental process. This step not only recycles nucleotides but also adjusts gene expression due to the availability of the mRNA templates. The main players in this process ... -
Arabidopsis thaliana class II TGA transcription factors provide a molecular link between salicylic acid and ethylene defense signalling
(2011-11-15)Since plants are exposed to a multitude of different attackers, a complex innate immune system has evolved to protect them from devastating diseases. Depending on the type of pathogen or ... -
Assessment of antibiotic resistance in soil and its link to different land use types and intensities
(2020-07-15)Nowadays, bacterial infections pose a serious risk for human health again, due to multi-resistant pathogens insensitive to antibiotic treatment. Some of the antibiotic resistance genes (ARGs) carried by these pathogens ... -
Bacillus subtilis biofilm formation under extreme terrestrial and simulated extraterrestrial conditions
(2020-05-25)Since the Apollo 16 mission in 1972, Bacillus subtilis served as bacterial model organism in space. Due to the ability to form highly resistant endospores and complex biofilms, it was used to investigate the effects of ... -
Bilaterale Koordination kommissuraler Interneurone im Mesothorakalganglion von Locusta migratoria migratorioides
(2009-03-26)Bilateral left-right-coordination of insect pairs of legs must involve commissural interneurons (CINs) which cross the midline of the segmental ganglion. This study describes two types ... -
Characterization of proteins of the Asp23 protein family in Bacillus subtilis
(2017-02-07)The acetyl-CoA carboxylase (ACCase) catalyzes the production of malonyl-CoA, the precursor in fatty acid biosynthesis. In almost all organisms, this is a fundamental process since fatty acids are the main components of ... -
Cyclic monophosphate cyclase in Firmicutes: from basic to practical approach
(2019-01-30)Cyclic di-adenosine monophosphate (c-di-AMP) is a second messenger involved in diverse metabolic processes such as cell wall homeostasis, biofilm formation, antibiotic and heat resistance, among others. In Lactococcus ... -
Der Einfluss der Glutamatdehydrogenasen auf die Verknüpfung des Kohlenstoff- und Stickstoffstoffwechsels in Bacillus subtilis
(2011-06-01)Glutamate is the central amino group donor for all nitrogen containing compounds in the cell. In the Gram-positive soil-dwelling bacterium Bacillus subtilis glutamate is exclusively synthesized ... -
Functional Characterisation of Ribosome Biogenesis Cofactors in Saccharomyces cerevisiae
(2015-02-11)The biogenesis of eukaryotic ribosomes is a highly complex and dynamic process, which requires a multitude of cofactors. In Saccharomyces cerevisiae, approximately 200 proteins have been identified to function in this ... -
Functions of the Cold Shock Proteins in Bacillus Subtilis
(2021-07-09)RNA binding proteins are fundamental to the proper functioning of all cells. They are structural components in larger complexes such as ribosomes or regulate cellular processes that involve RNA such as transcription, ... -
Funktionale Analyse des CC-Typ Glutaredoxin ROXY19 in Arabidopsis thaliana
(2019-02-05)Glutaredoxins are small widespread enzymes that are characterized by the so-called thioredoxin fold. They have an active center which can be reduced by glutathione. The glutaredoxins are divided into three classes according ... -
Identification and Functional Characterization of unc5A during Neocortical Regionalization
(2008-04-15)During the evolution of mammalian species, the cerebral neocortex acquired improved sensory, learning, and decision-making activities in parallel to its structural regionalization for specific functions. Each of these ... -
Identifizierung und Charakterisierung der Dihydroorotat Dehydrogenase als Zielstruktur von 1-Hydroxyquinolonen in Toxoplasma gondii
(2014-01-06)1-Hydroxyquinolones were recently described as effective inhibitors of Toxoplasma gondii replication. These compounds (e.g. HDQ and compound B) were previously shown to inhibit the alternative NADH dehydrogenase (NADH2-I) ... -
IFN-γ-vermittelte Infektabwehr von <i>Toxoplasma gondii</i> in murinen Skelettmuskelzellen <i>in vitro</i>
(2011-05-17)Toxoplasma gondii is a widespread intracellular parasite which is able to infect any nucleated cell of warm-blooded animals and humans leading to a lifelong persistence of T. gondii ... -
Impact of rainforest conversion: How prokaryotic communities respond to anthropogenic land use changes
(2020-12-03)In this thesis, the impact of rainforest conversion to the managed land use systems jungle rubber, rubber plantation and oil palm plantation on structure and function of soil microbial communities was investigated. The ... -
Impact of Toxoplasma gondii on STAT1 activity and epigenetic regulation during IFN-γ signaling of its host cell
(2018-08-21)Toxoplasma gondii is an obligate intracellular parasite which infects up to 30% of humans world-wide. To control T. gondii, the host mounts a strong IFN-γ-driven immune response via the signal transducer and activator of ... -
Insights into the regulation of RNA helicases by protein cofactors
(2019-02-12)RNA helicases comprise a large family of ubiquitously expressed enzymes that remodel RNA structures and RNA-protein complexes in an NTP-dependent manner. These proteins are essential regulators of every RNA-related process, ... -
Intramembrane signal transduction and cell envelope stress response in <i>Bacillus subtilis</i>
(2008-02-04)The bacterial cell envelope is the first and major line of defence against threats from the environment. It is an essential and vulnerable structure that gives the cell its shape and ...