Dokumente Fakultät für Biologie und Psychologie (inkl. GAUSS) nach Gutachter "Stegmüller, Judith Dr."
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Analyses of improved long term memory in SHARP1 and SHARP2 double knockout mice
(2015-09-15)The transition of recent experiences into stable and remote memory traces is an important task that mainly occurs during sleep. Sleep-associated consolidation of remote long-term memory is based on cortical networks that ... -
Analysis of protein SUMOylation and its role in Alzheimer's disease using mouse models
(2017-04-26)Post-translational modifications serve as a cellular mechanism for the regulation of the activity, stability and localization of proteins. SUMOylation is a dynamic and reversible post-translational modification, which ... -
HECT-type Ubiquitin Ligases in Nerve Cell Development
(2016-10-11)Development of neurons begins in the middle of embryogenesis after closure of the neural tube. In the process of neurogenesis, neural stem cells generate nerve cells by asymmetric cell divisions at the ventricular zone of ... -
Investigation of myelin membrane adhesion and compaction in the central nervous system
(2013-02-13)Myelin is a multi-layered membrane which enwraps the axons in peripheral (PNS) and central nervous system (CNS). The formation and assembly of this structure is a multi-step process that is regulated by a variety of ... -
The Role of the E3 Ubiquitin Ligase Cdh1-APC in Axon Growth in the Mammalian Brain
(2012-09-14)Neuronal differentiation begins with initiation of the axon. Both extrinsic factors in the neuronal environment and cell-autonomous players contribute to successful axonal morphogenesis. The E3 ubiquitin ligase, ...