Dokumente Fakultät für Biologie und Psychologie (inkl. GAUSS) nach Gutachter "Stein, Alexander Dr."

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    • Biochemical characterization of human shieldin complex 

      Susvirkar, Vivek (2022-08-01)
      Shieldin is a newly identified DNA repair effector involved in repair of double strand breaks (DSBs) in G1 phase of cell cycle. Shieldin is a four-component complex consisting of proteins SHLD1, SHLD2, SHLD3 and HORMA REV7. ...

    • HORMA domain proteins in Autophagy initiation 

      Lugarini, Francesca (2022-08-01)
      The autophagic pathway is an evolutionarily conserved strategy among eukaryotic cells for maintaining cell homeostasis at the basal level and during stressful conditions. It removes protein aggregates, damaged organelles, ...

    • Structural characterization of human spliceosome activation by cryo-EM 

      Townsend, Cole (2022-01-27)
      Eukaryotic genes are transcribed as precursor mRNA (pre-mRNA), in which coding regions (exons) are interrupted by non-coding regions (introns). Introns are excised and exons are ligated together in a two-step process ...