Dokumente Fakultät für Biologie und Psychologie (inkl. GAUSS) nach Gutachter "Wimmer, Ernst A. Prof. Dr."
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A novel pathway for VLDL assembly in the mouse liver
(2006-12-11)LDL is thought to be endocytosed and completely degraded by peripheral cells and the liver. Using primary mouse hepatocytes, mouse liver perfusion and intravenous LDL-injection in mice, it ... -
Analyses of improved long term memory in SHARP1 and SHARP2 double knockout mice
(2015-09-15)The transition of recent experiences into stable and remote memory traces is an important task that mainly occurs during sleep. Sleep-associated consolidation of remote long-term memory is based on cortical networks that ... -
Analysis of peroxisomal turnover and myelin maintenance in mice with oligodendrocyte-specific MFP2-deficiency
(2016-11-02)Although caused by distinct genetic mutations, the peroxisomal disorders X-linked adrenoleukodystrophy (X-ALD), pseudoneonatal adrenoleukodystrophy (pseudo NALD), and neonatal adrenoleukodystrophy (NALD) share several ... -
Analysis of two kinetically distinct components of transmitter release at a fast synapse of the mammalian central nervous system
(2006-01-06)Two kinetically distinct components of transmitter release have been observed in Ca2+ uncaging experiments at a CNS synapse in rats, and both release components showed a steep dependence ... -
Application of RNA Interference for the Study of Lethal Genes and Dynamic Processes
(2016-02-08)RNA interference (RNAi) is a highly conserved cellular mechanism and in the last years it has become to a major tool for functional analyses of genes in different species. Moreover, RNAi has recently been suggested as a ... -
Bilaterale Koordination kommissuraler Interneurone im Mesothorakalganglion von Locusta migratoria migratorioides
(2009-03-26)Bilateral left-right-coordination of insect pairs of legs must involve commissural interneurons (CINs) which cross the midline of the segmental ganglion. This study describes two types ... -
Biology of odoriferous defensive stink glands of the red flour beetle Tribolium castaneum
(2015-09-15)Chemical warfare is a very common defense strategy in the insect world. A broad range of coleopteran beetles react to predators, invaders, and parasitic microbes with the release of toxic and repellent substances, which ... -
Biotechnological approaches to fight fruit flies of agricultural importance
(2012-10-08)Tephritid fruit flies destroy fruits and vegetables, causing tremendous economic losses and bringing a barrier to trade in fruits, vegetables and their associated products. The Sterile Insect Technique (SIT), a target-specific ... -
Brain derived neurotrophic factor (BDNF): Untersuchungen zur Expression und Regulation in vitro sowie zur funktionellen Relevanz in der experimentellen autoimmunen Enzephalomyelitis (EAE)
(2010-07-14)The neurotrophin brain derived neurotrophic factor (BDNF) is essential for the development and maintenance of the nervous system. Neurons are the main cellular source of this neurotrophin, ... -
Characterization of foetal hepatic cells during rat liver development
(2006-11-06)During embryonic development the embryonic/foetal liver is the site where hepatogenesis and hematopoiesis take place. Hepatoblasts have been partly characterized in several previous studies. ... -
Characterization of proneural bHLH transcription factor target genes in X. laevis
(2022-09-23)Zc3h12c is a member of the Zc3h12 endoribonuclease family (also known as MCPIP/Regnase), which contains four members (Zc3h12a-c). This family of proteins is characterized by the presence of a single centrally located ... -
Comparative DNA‐Protein Interaction and Epithelial Tight Junctions Modulation Potential of Immunosuppressive Regime
(2016-01-28)Mycophenolic acid (MPA) is an important immunosuppressive drug (ISD) prescribed to prevent graft rejection in the organ transplanted patients. However, its use is sporadically linked to the leak flux diarrhea and other ... -
Comprehensive Morphological and Transcriptomic Analysis of the Chemosensory System in the Red Flour Beetle, Tribolium castaneum
(2016-11-18)The red flour beetle, Tribolium castaneum is an emerging coleopteran model system and thus represents the largest insect order with several agricultural and forest pests. Despite the ecological and economic importance of ... -
Computational analysis of transcriptional regulation and chromatin assembly
(2023-12-07)Primordial germ cells (PGCs), the precursors of gametes, are specified from post-implantation epiblast cells in response to bone morphogenetic protein (BMP) signaling at the onset of gastrulation in mouse. Followed by ... -
Determination of Genetic Interactions Required for Dystrophin-Dystroglycan Function and Regulation in a Drosophila Model of Muscular Dystrophy
(2010-01-20)In humans genetically diverse forms of muscular dystrophy (MD) are associated with a disrupted Dystrophin-Glycoprotein Complex (DGC). The DGC consists of dystrophin, dystroglycans, sarcoglycans, ... -
Development and metamorphosis in the male pedipalp of the cob-web spider Parasteatoda tepidariorum
(2019-02-12)Tracing from marine ancestors, spiders have adapted to a terrestrial lifestyle independent from the insects. Many of the adaptations of spiders to life on land involve the shape and function of their appendages. From these ... -
Development of a biotechnologically enhanced sterile insect technique to fight coleopteran pests
(2021-06-30)Tribolium castaneum commonly referred to as the Red Flour Beetle (RFB) belongs to the class Insecta and order Coleoptera, and it’s the best model organism for coleopterans. About 380,000 coleopteran species, constituting ... -
Development of Transgenic Sterile Insect Technique Strains for the Invasive Fruit Pest Drosophila suzukii
(2020-12-03)Globalization has contributed enormously to emergence and expansion of invasive pests. A recent example is the invasion in Europe and the USA by the cherry vinegar fly Drosophila suzukii. The pest has high potential to ... -
Differential gene expression of chemokines in KRAS and BRAF mutated colorectal cell lines: Role of cytokines
(2013-06-07)Background: Worldwide, colorectal cancer is the third most common malignancy. The development of the colorectal cancer (CRC) is a multistep process that involves e.g. an accumulation of mutations in tumor-growth promoting ... -
Downstream targets of transcription factor Pax6 in cortical development
(2008-04-22)Pax6 is a transcription factor with key functional roles in patterning and arealization of the cortex. We studied regulation of gene expression in Pax6 mutants through microarray analysis. This allowed us to focus on ...