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• Enhancing RNAi-Based Pest Control through Effective Target Gene Selection and Optimal dsRNA Design 

  Cedden, Doga (2025-12-04)

  The growing global population demands new strategies for sustainable pest management. Chemical insecticides, while historically successful in controlling pest populations to protect agricultural yields and suppress disease ...

• Generation and characterization of an otic bioengineered neuronal organoid (oBENO) from human pluripotent stem cells 

  Koufali, Angeliki (2025-12-03)

  Hearing loss impacts nearly 20% of the global population, and according to estimations its prevalence will increase by 2050, affecting around 1 in 4 individuals. The most common form of hearing impairment, sensorineural ...

• Community assembly processes of intertidal salt marsh microarthropods 

  Haque, Md Ekramul (2025-12-01)

  Salt marshes are highly dynamic ecosystems at the land–sea interface, shaped by steep environmental gradients and frequent disturbances. They provide critical ecosystem services, including coastal protection, nutrient ...

• Untersuchungen zum Wasserhaushalt tropischer Bäume in Abhängigkeit von der Meereshöhe in Süd-Ecuador 

  Schuldt, Bernhard (2025-11-27)

  The scope of this research study examines the influence elevation has on the water status in tropical montane rainforests in southern Ecuador. The investigation focused upon the vessel anatomy of branches and roots as well ...

• Ecological and functional significance of plant hydraulics in a changing climate 

  Schuldt, Bernhard (2025-11-27)

  This habilitation treatise evolved from seven years of postdoctoral work in the Department of Plant Ecology and Ecosystem research at the University of Göttingen. During this time, I had the opportunity to continue my ...

• Network hyperexcitability and dopaminergic neuron loss in a novel A30P-driven Parkinson’s midbrain organoid model 

  Schmoll, Kea Aline (2025-11-24)

  Midbrain dopaminergic (mDA) neurons are essential for motor control, reward processing, emotional regulation and motivation. The degeneration of these neurons, seen in Parkinson’s disease (PD), disrupts fine motor control, ...

• Uncovering the interactome of peripheral myelin protein 22 kDa (PMP22) to understand its role in health and neuropathy 

  Stausberg, Daniela Katharina (2025-11-20)

  PMP22, a hydrophobic glycoprotein, is crucial for proper myelination in Schwann cells of the peripheral nervous system. Dosage alterations lead to the neuropathies Charcot-Marie-Tooth disease 1A (CMT1A), where PMP22 is ...

• Functional relevance of oligodendroglial CDC42 effector proteins CDC42EP1 and CDC42EP2 in myelin morphogenesis 

  Hümmert, Sophie (2025-11-12)

  Myelin sheaths are composed of multiple compacted membrane layers that tightly encase the underlying axon. Structural abnormalities of myelin indicate pathological processes and are frequently associated with neurological ...

• Computational analysis of nucleosome assembly and cis-regulatory DNA elements 

  Dovgusha, Oleksandr (2025-11-12)

  Induced pluripotent stem cells (iPSCs) represent embryonic stem cells (ESCs) that are reprogrammed from somatic stem cells. iPSCs can be directed to differentiate into any cell type in the human body, therefore, holding ...

• Comparative Cognitive Flexibility Assessment: Multidimensional set-shifting in monkeys, adult humans and children and adolescents with Attention Deficit Hyperactivity Disorder (ADHD) 

  Yurt, Pinar (2025-11-10)

  This thesis aims to provide a be0er and more comprehensive understanding of one of the crucial execu8ve func8ons: cogni8ve flexibility (Chapters 2 and 3). To that end, we have developed a novel mul8-dimensional set-shiEing ...

• Optimierung der Diagnostik von der Posttraumatischen Belastungsstörung und der komplexen Posttraumatischen Belastungsstörung nach ICD-11 

  Treptow, Marit (2025-10-30)

  The establishment of the diagnosis of complex post-traumatic stress disorder (cPTSD) in the new classification system (ICD-11) has brought with it new diagnostic procedures. However, these procedures do not differentiate ...

• Role of bacterial rhamnolipids in plant tolerance to abiotic stresses 

  Bouchrati, Maoulida Ali (2025-10-29)

  Rhamnolipids (RLs), glycolipids produced by Pseudomonas and Burkholderia species, have been described as potential biocontrol agents due to their antagonistic activity against pathogens and their ability to induce plant ...

• Bringing bioinformatics to the bench: SubtiWiki 5.0 and new web tools for research 

  Elfmann, Christoph (2025-10-29)

  Model organisms are central to biological research, as their study provides crucial insights into fundamental processes of life and enables biotechnological applications. The intensive research on these organisms spans ...

• Complex Coacervation of Disordered Proteins: focus on α-Synuclein and Polyamines 

  Percival, Matthew (2025-10-28)

  The discovery of phase-separated bodies in cells has revealed an additional mesoscale layer of organisation in cellular and molecular biology. The enrichment of RNA in these biomolecular condensates suggests that charge ...

• Addressing Habits in Anorexia Nervosa 

  Zielke-Rössel, Eva Dorothea (2025-10-23)

  Anorexia Nervosa (AN) is a mental disorder that affects up to 0.3% of men and 6.2% of women worldwide and places a significant burden on the individual, their social environment and the healthcare system. Although ...

• Studies on Testicular Development and Aging in the Common Marmoset (Callithrix jacchus) and the Establishment of Somatic Testicular Cell Lines 

  Hassan, Syed Bilal (2025-10-15)

  The phenomenon of reproductive ageing in women has been known for a long time and some aspects of this phenomenon are well understood. However, ageing effects in the testes were not recognized for a long time, as aged males ...

• Design-based Research on Promoting Relevance Perceptions in Socioscientific Teaching and Learning – Sustainable Oil Palm Cultivation in Science Teacher and Forestry Education 

  Matthiesen, Finn Kristen (2025-10-02)

  Recent interdisciplinary scientific research has suggested evidence-based management strategies for more sustainable oil palm cultivation, such as reducing agrochemicals and establishing agroforestry systems. For this ...

• The evolution of an unusual adult sex ratio in wild redfronted lemurs (Eulemur rufifrons) 

  Pethig, Leonie (2025-09-19)

  Variation in adult sex ratios (ASR), defined as the proportion of adult males to females, reflects complex demographic and evolutionary processes. Female-biased ASRs characterize the vast majority of non-monogamous mammals, ...

• Investigations towards a link of morphodynamics and transcriptional pattern in embryonic tissues during morphogenesis 

  Abbaszadeh, Roya (2025-09-16)

  The acquisition and loss of epithelial characteristics—such as apico-basal polarity, cell–cell adhesion, and barrier integrity—are essential processes during development, regeneration, and disease. While epithelial–mesenchymal ...

• Advancing soil nematode research: molecular, morphological and stable isotope analyses 

  Wang, Simin (2025-09-16)

  The overarching aim of this dissertation was to explore the impact of environmental variances on soil nematode communities, their trophic interactions and their ecological roles by integrating traditional morphological ...

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