Fakultät für Biologie und Psychologie (inkl. GAUSS)
Recent Submissions
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Evolution of polyploidy and apomixis in the pantropically distributed and species-rich genus Zanthoxylum (Rutaceae)
(2025-04-22)The proto-Rutaceae group includes genera with significant economic and evolutionary importance, yet their phylogenetic relationships and evolutionary mechanisms remain incompletely understood. This thesis focuses on the ... -
Lying with Deceptive Implicatures: The Roles of Commitment, Culture, and Partisan Bias
(2025-03-25)The aim of the present work is to advance our understanding of how ordinary speakers use the term lying to categorize deceptive behaviours they inevitably encounter in their everyday lives. Although a firm grasp of how ... -
Social evaluation and decision-making in nonhuman primates
(2025-03-25)One of the challenges of living in a group is constantly having to decide when, how, and whom to interact with among several conspecifics in plenty of different contexts. For optimal decision-making, social animals can ... -
The role of chromatin hubs in the regulation of gene expression and maintenance of genomic integrity
(2025-03-20)The correct development and functioning of complex organisms rely on precise spatiotemporal regulation of gene expression and on efficient maintenance of their genomic stability. Regulation of gene expression during ... -
The Melody of Miscommunication in the Heart Decoding LZTR1 deficiency with a Multicellular Focus
(2025-03-20)LZTR1 deficiency is a known cause of Noonan syndrome (NS) and is linked to early-onset and severe hypertrophic cardiomyopathy (HCM). Despite the recognized importance of paracrine communication in cardiac pathology, the ... -
Fast inference in flexible high dimensional models of gene co-expression and genotype-gene expression interaction
(2025-03-20)As more high-throughput sequencing data is produced from ever-growing human cohorts, understanding human biology becomes a more and more quantitative and statistical task. Starting notably with the data made available in ... -
Decision-making under risk in Barbary macaques (Macaca sylvanus)
(2025-02-24)Risk is ubiquitous in the everyday lives of all animals. Individuals often face precarious situations, such as unpredictable resources and exposure to predators, in which their decisions may lead to a variety of possible ... -
The roles of long non-coding RNAs in CNS diseases with a focus on astroglial-neuronal communication
(2025-02-14)Aging is accompanied by a decline of cognitive functions and represents a major risk factor for the development of neurodegenerative diseases such as Alzheimer’s disease (AD). Key pathological changes linked to AD are the ... -
A nidulans development and secondary metabolism requires coordinated VeA nuclear import and export
(2025-02-14)Survival of multicellular organisms requires the functional interplay between complex regulatory networks including gene expression, the ubiquitin proteasome protein degradation system, and intracellular transport control. ... -
Alpha-synuclein amyloid aggregation: From basic to translational research
(2025-02-05)Neurodegenerative diseases are a heterogeneous group of disorders affecting the lives of millions of people worldwide. A shared pathologic hallmark is the appearance of insoluble aggregates in the brain. The components of ... -
Single-cell studies of mammalian ovaries
(2025-01-31)Ovarian aging progresses more rapidly than in other organs. Female fertility declines exponentially after the age of 35, and as women increasingly delay childbearing, it is paramount to understand the underlying etiology ... -
Proteogenomic peptide discovery in large search spaces
(2025-01-30)Novel peptide and protein discovery is of therapeutical relevance and ignited the development of methods for their identification, commonly done via mass spectrometry. The latter relies on a well-characterised proteogenomic ... -
Microbial Communities in the Terrestrial Subsurface
(2025-01-23)Terrestrial subsurface habitats represent a significant portion of Earth's prokaryotic biomass. However, our understanding of microbial diversity and functions in these environments, particularly in arid regions, remains ... -
Children’s Language Learning and Processing in Digital Social Interactions
(2025-01-10)Language is inherently a social tool, and nearly all questions concerning its origins, development, and processing raise a discussion of social interactions. As technological advancements transform how we communicate – ... -
The long-term effects of fire, climate, and human impact in the highland and lowland ecosystems of Sumatra Indonesia
(2025-01-09)Sumatra, Indonesia is one of the outstanding biodiversity hotspots of the world. Over the past few decades, the primary forests of this island, from the highlands to the lowlands, have experienced a remarkable transformation ... -
Time-sensitive reconstruction of joint evolutionary trees in a host-parasite model with host switches
(2024-12-20)This thesis focuses on mathematical models that describe the joint evolution of host-parasite systems in the presence of host switches, or in other words, horizontal transfers. This is a phenomenon where a parasite individual ... -
Social evaluation and partner choice in the tolerant multi-level society of Guinea baboons
(2024-12-18)Group living animals must navigate complex social environments, continuously updating their knowledge of group members to help them make appropriate social decisions in both competitive and cooperative interactions with ... -
Structural basis of human mitochondrial RNA processing
(2024-12-16)Mitochondrial transcription produces polycistronic transcripts, in which ribosomal RNA (rRNA) and messenger RNA (mRNA) regions are interspersed with transfer RNA (tRNA) sequences. Endonucleolytic cleavages at the 5' and ... -
The dual role of MTG3 during human mitoribosome biogenesis
(2024-12-05)Mitochondria are the main energy provider of the cell, and because of the endosymbiotic event they arise from, still contain a small independent genome. Only with the vast ATP production through the mitochondrial OXPHOS ... -
Computational Analysis of Prognostic Factors, Immune Microenvironment, and T-Cell Receptor Repertoires in Lymphoma
(2024-11-22)The immune system plays an important role in the development and progression of cancer. While solid cancers like carcinomas primarily affect specific organs and tissues, hematologic malignancies are not always so localized, ...