Browsing Fakultät für Agrarwissenschaften (inkl. GAUSS) by Advisor & Referee "Brenig, Bertram Prof. Dr. Dr."
Now showing items 1-20 of 25
-
Molekulargenetische und proteinanalytische Untersuchungen trächtigkeitsassoziierter Glykoproteine beim Rind
(2022-10-11)The dissertation addresses molecular genetic and protein analytical studies of bo-vine pregnancy-associated glycoproteins (boPAGs) and their practical application as pregnancy markers. Bovine PAGs are expressed by trophoblast ... -
Identification of molecular genetic causes of bull infertility
(2021-11-18)This is a cumulative thesis that includes three different topics around male infertility in cattle and canine diseases. Whole genome association analysis (GWAS) and whole genome sequencing (WGS), as well as additional ... -
Genetic Analysis of Dog Congenital Deafness and Herding Behavior
(2021-10-05)Strong artificial selections of canine morphological and behavioral traits lead to the formation of more than 400 modern dog (Canis familiaris, CFA) breeds within the past 300 years. Most dog breeds are derived from small ... -
Selection and characterization of human recombinant antibodies against Orthopoxviruses from an immunoglobulin library and mapping of functional epitopes of Vaccinia virus surface proteins
(2020-04-07)The genus Orthopoxvirus (OPXV) contains a group of large (130-380 kb) and closely related double-stranded DNA viruses within the Poxviridae family, which replicates in the cytoplasm of vertebrate or invertebrate cells. ... -
Identification of molecular-genetic causes for osteogenesis imperfecta, interdigital hyperplasia and ribosomopathies in cattle
(2020-02-06)Musculoskeletal anomalies are a heterogeneous group of fairly common, often with severe clinical symptoms, but mostly fatal disorders in human and animals. By far, complex vertebral malformation (CVM) and Brachyspina are ... -
Molekulargenetische Untersuchungen zu Augenerkrankungen beim Holstein Friesian Rind
(2017-09-29)The current study deals with ophthalmological anomalies in Holstein Friesian (HF) cattle and is divided into two parts. The first part of the study considers the development of congenital cataracts in HF cattle. In total ... -
Identification of molecular role of Pelota protein in proliferation and differentiation of male germ stem cells by analysis of conditional knock-out mice
(2015-05-27)Pelota (Pelo) is an evolutionally conserved gene, which has been characterized in various species. In Drosophila, Pelo deficiency affects both male and female fertility. The molecular function of PELO has been extensively ... -
Aufklärung aktueller tierzüchterischer und verbraucherrelevanter Fragestellungen durch molekulargenetische Strategien
(2014-08-26)Claw diseases and disorders are the third leading reason for dairy cows leaving the herds and 90% of lameness cases are due to various claw diseases. As part of the FUGATO-plus GENE-FL project, the genetic causes of ...
-
Dissection of molecular basis on a causative mutation for ear size QTL on chromosome 7 in pigs
(2013-07-15)The pinna，an important component of the external ear, first appeared in mammals. It plays a vital role in collecting sounds, radiating heat and signaling mood. In humans, the most common ear defect is microtia with prevalence ... -
Functional analysis of Zfp819 in pluripotency and embryonic development
(2013-03-21)Pluripotency is established and maintained by many pluripotent stem cell-specific transcription factors such as Oct3/4, Nanog, and Sox2 and by the function of their coordinated regulatory network. Several studies have ... -
Untersuchungen zur Rolle von Klf10 und Klf11 als Mediatoren von NGF- und TGF-β-vermittelten Effekten in Zellen neuraler Herkunft
(2012-11-15)The TGF-β1/Klf-family of transcription factors. They play important roles in development and maintenance of various tissues and cell types. The publications consolidated in this thesis describe, that Klf11 mimics TGF-β ... -
Temperature Dependent Sex Determination In Zebrafish (Danio rerio)
(2012-02-23)Summary Despite zebrafish (Danio rerio) is an important model for understanding vertebrate development during the last decades, sex determination and differentiation are not ... -
Molekulargenetische Untersuchungen zur Verbesserung der männlichen Fruchtbarkeit und Bekämpfung des Erbdefektes Hernia inguinalis/scrotalis in der Schweinezucht
(2010-02-10)Artificial insemination (AI) is a very common and efficient reproduction method in pig breeding. About 90% of all breeding sows in Germany were inseminate by artificial insemination in 2007. ... -
Analysis of DNA sequence variants in candidate genes for bovine spongiform encephalopathy (BSE) susceptibility located in a QTL region on bovine chromosome 17q23-q24
(2010-02-08)Bovine spongiform encephalopathy (BSE) belongs to a group of diseases called transmissible spongiform encephalopathies (TSE). With the occurrence of the BSE crisis, several studies have ... -
Molekulargenetische und physiologische Untersuchungen zur Vererbung des Erbdefektes Hernia inguinalis/scrotalis beim Schwein
(2009-11-20)Hernia inguinalis/scrotalis (i/s) in pigs are known as congenital defects which occur with a frequency of 1-3% and a heritability of h2 = 0.02 to h2 = 0.86 in German pig breeds and ... -
A Whole Genome Scanning for QTL Affecting Leg Weakness and Its Related Traits in a White Duroc × Erhualian Resource Population
(2009-02-23)A linkage map comprising 194 microsatellite markers across the pig genome was constructed with a large scale White Duroc × Erhualian resource population. The marker order on this linkage ... -
Handbuch der monogenen Erbmerkmale beim Hund
(2008-10-01)The objective of the present thesis was to compile all monogenic hereditary diseases and traits whose molecular genetic causes have been identified to date (status quo in October 2007). ... -
Genomanalyse beim landwirtschaftlichen Nutztier
(2008-05-09)The thesis is divided into two parts. The studies presented in the first part describe the results of molecular analyses on the inheritance of congenital inguinal and scrotal hernia in the pig. The second part covers ... -
Towards the genetic dissection of the complex maternal infanticide behaviour using a white Duroc x Erhualian pig F2 design
(2008-03-18)Aggressive behaviour by newly farrowed sows towards their own offspring, known as savaging or maternal infanticide, occurs commonly in the domestic pig, with a significant impact upon both the agricultural economy and ... -
Deciphering the genetics of pig complex traits through QTL mapping and positional candidate cloing
(2007-02-12)Most traits in livestock are controlled by multiple genes and are therefore called genetically complex traits. In this thesis, we firstly report the molecular characterization and evaluation ...