Dokumente GZMB - Göttinger Zentrum für molekulare Biowissenschaften nach Gutachter "Doenecke, Detlef Prof. Dr."
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Characterization of Mitochondrial Calcium Uniporter in Barth Syndrome Models
(2020-07-15)The Barth Syndrome (BTHS) is caused by the loss of the mitochondrial acyltransferase tafazzin, which is involved in the remodeling process of the hallmark mitochondrial glycerophospholipid cardiolipin. Cardiolipin maintains ... -
Proteome-wide Identification of New Molecular Targets Affected by Methotrexate in Acute Promyelocytic Leukaemia Cell Line
(2007-06-11)Methotrexate (MTX) was first introduced as a cytotoxic agent that inhibits nucleotide biosynthesis in various cancer disorders. Accumulating evidences suggest that MTX inhibits the proliferation of malignant cells by ...