Browsing Fakultät für Chemie (inkl. GAUSS) by Referee "Ackermann, Lutz Prof. Dr."
Now showing items 21-40 of 77
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Dynamics, Intermolecular Interactions, and Organization of Transmembrane β-Peptides
(2018-02-01)Cellular membranes contain a vast variety of proteins, which are practically required for every vital mechanism, such as selective transportation of ions and organic molecules, cell-cell recognition and signal transduction.[1] ... -
Earth-Abundant Transition Metal-Catalyzed Electro-Reductive Cross-Electrophile Coupling Reactions and C–H Activation by Cobaltaelectro-Catalysis
(2021-12-13)Within the last decades, immense progresses have been made with transition metal-catalyzed cross-electrophile reactions and C–H activation reactions. The merger of electrocatalysis with such powerful methods have further ... -
Electrochemical Benzylic C−H Fluorination and 4d-Metallaelectro-Catalyzed C−H and C−C Functionalizations
(2023-03-15)Direct functionalizations of C−H and C−C bonds have emerged as time-saving and cost-effective alternatives to established cross-coupling reactions. However, oxidative coupling variants require stoichiometric amounts of ... -
Electrochemical C-H Activations with 3d and 4d Transition Metal Catalysts
(2021-12-20)The oxidative metal-catalyzed C–H activation of inert bonds is a powerful tool for the functionalization of complex molecules. This platform allowed the broadening of the organic chemists’ toolbox and improved the ... -
Electronic Structure and Reactivity of Bioinspired Organometallic Iron Complexes Relevant to Small Molecule Activation
(2017-06-15)This PhD thesis focuses on the development and characterization of new organometallic iron complexes as models for abundant enzymatic systems. The use of a macrocyclic tetracarbene ligand system results in novel features ... -
Entwicklung regio- und enantioselektiver Transformationen an Alkenen mittels λ3-Iodan-Reagenzien bzw. chiraler Selen-π-Säure-Katalysatoren
(2020-09-02)In this thesis three novel oxidative functionalisations of alkenes are presented. The focus lay on the one hand on the development of the first aerobic phosphatation of alkens using a dual selenium-pi-acid-photoredox ... -
Experimental and Computational Studies on Ruthenium- and Manganese-Catalyzed C-H and C-C Activation
(2019-11-07)During the last years, transition metal-catalyzed C–H and C–C activation has emerged as a powerful tool for the selective construction of C–C and C–Het bonds. In this context, a detailed mechanistic understanding of these ... -
Exploring Metal-Ligand Interactions of Pyrrole Based Pincer Ligands
(2014-02-18)This thesis is based on the exploration of metal-ligand interactions of pyrrole based pincer ligands. By analyzing the carbon-carbon bond lengths within the pyrrole heterocycle inferences were drawn about the metal-ligand ... -
Homogeneous and Heterogeneous Chelation-Assisted Ruthenium(II)-Catalyzed C–H Functionalizations
(2017-01-03)Ruthenium(II)-catalyzed direct C–H functionalizations have emerged as a powerful tool for organic chemists to construct C–C and C–Het bonds. In order to rationally improve the efficiency of these methods a mechanistic ... -
Investigations towards the design, synthesis and application of new sulfur-based transfer reagents
(2019-06-20)New dibenzothiophenium-based alkynylation reagents were prepared and their versatile reactivity was demonstrated in reactions with benchmark C-, S-, N- and P-nucleophiles. Straightforward experiments applying 13C-labeled ... -
Iron- and Ruthenium-Catalyzed Site-Selective C–C Forming Direct C–H Functionalizations
(2015-04-09)During the last decades, C‒C bond forming reactions have been established as one of the most important tools for modern organic synthesis for the functionalization of otherwise difficult to activate compounds. The inexpensive ... -
Iron-Catalyzed C–H/N–H Activations for Annulation of Allenes, Alkynes, and Bicyclopropylidenes
(2020-11-16)Iron-catalyzed C–H/N–H activations for the annulation of allenes, alkynes, and bicyclopropylidenes were realized by using a customizable clickable triazole amide under mild reaction conditions. The powerful iron catalysis ... -
Kupfer- und palladiumkatalysierte N H- und C H-Bindungsfunktionalisierungen zur effizienten Synthese von Heterocyclen
(2011-05-20)Several approaches for the synthesis of substituted indoles, (benz)oxazoles and oxazolines using copper- and palladium-catalyzed reactions are examined. A copper-catalyzed synthesis of ... -
Late-Stage Peptide Diversification via Transition Metal-Catalyzed C─H Activation
(2020-10-13)The late-stage modification of peptide is of great value to drug discovery and medicinal chemistry. Metal catalyzed C─H activation has emerged as efficient and step-economic strategy for post-translational peptide engineering. ... -
Late-Stage Peptide Functionalization by Ruthenium-Catalyzed C H Arylations and Alkylations
(2018-11-08)The thesis contents methods for the selective activation and functionalization of C–H bonds of the C2 position of a tryptophan moiety incorporated into peptides. Palladium-catalyzed C-H arylation reactions applying ... -
Late-Stage Peptide Functionalization by Transition Metal-free and Palladium-Catalyzed C–H Arylations
(2022-03-31)The focus of this thesis was set on the late-stage modification of peptides through transition metal-free and palladium-catalyzed C–H arylations. At first, the scope of the transition metal-free C2-arylation of the ... -
Merging Electrosynthesis with 3d Transition Metal-Catalyzed C–H Transformations
(2021-07-12)In recent years, oxidative C–H transformations have emerged as increasingly powerful tools in molecular syntheses. However, despite great progress towards more atom and step economic synthetic methods, oxidative couplings ... -
Metal complexes of a new polyimido sulfur phosphanyl ligand
(2015-02-10)Within this thesis, a new synthetic access to diverse metal complexes of polyimido sulfur phosphanyl ligands was developed. The coordination behaviour of either the lithiated ligand [(tmeda)Li{(NtBu)3SCH2PPh2}] (1) or the ... -
METAL COMPLEXES OF SCORPIONATE-LIKE POLYIMIDO SULPHUR PHOSPHANYL LIGANDS
(2011-11-01)In this thesis a new synthetic access to side-arm functionalized sulphur diimide ligands is developed. They can be tuned in their steric demand as well as in their electronic properties. ... -
Mikroskopische Reaktivität Metallorganischer Spezies
(2023-03-15)In oder to better understand cross-coupling reactions, the oxidative addition between organo halides and organometallates based on iron, cobalt and copper was investigated by using ion-molecule reactions in the gas phase. ...