Browsing Fakultät für Chemie (inkl. GAUSS) by Advisor & Referee "Ackermann, Lutz Prof. Dr."
Now showing items 21-40 of 90
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Merging Electrosynthesis with 3d Transition Metal-Catalyzed C–H Transformations
(2021-07-12)In recent years, oxidative C–H transformations have emerged as increasingly powerful tools in molecular syntheses. However, despite great progress towards more atom and step economic synthetic methods, oxidative couplings ... -
Resource-Economical C–H Activation for Late-Stage Functionalization
(2021-07-07)Organic synthesis has traditionally relied on step-, time- and resource-intensive strategies, namely the functional group interconversion and, more recently, on cross-coupling reactions. These approaches have enabled the ... -
Resource-Economical Synthesis by Selective Metal-Catalyzed C–H Activations
(2021-04-30)The advent of new synthetic strategies has enriched the synthetic organic chemistry to access molecules with tremendous complexity. In this context, transition metal-catalyzed C−H activation has emerged as a powerful tool ... -
C–H and C–F Activation by Manganese, Nickel and Ruthenium Catalysis
(2021-04-19)The development of novel environment-friendly, step- and atom-economical methodologies is one of the main goals in organic chemistry. In this context, the direct functionalization of inert C–(Het) and C–H bonds has ... -
Design and synthesis of multifunctional ligands to study and prevent aggregation processes in Amyotrophic Lateral Sclerosis proteins
(2021-02-22)Amyotrophic lateral sclerosis (ALS) is an incurable lethal disease that affects motor neurons and its heterogeneity is reflected in various mutations among the sporadic ALS (sALS) and familial ALS (fALS) disease types. ... -
Selective C–H Activation by Ruthenium(II) Carboxylate and Nickelaelectro-Catalysis
(2021-01-28)This doctoral thesis was divided into two main parts. In the first part, ruthenium(II)-catalyzed ortho-C–H alkynylations of diverse benzoic acids were achieved for the synthesis of aromatic alkynes. And meta-C–H activations, ... -
Synthesis and reactivity of succinylthioimidazolium salts: A unified strategy for the preparation of thioethers
(2020-12-21)Sulfur is one of the main group elements on our planet with a natural abundance of (0.46±0.15)w%. In its most common allotropic form sulfur is a yellow powder and exhibits a cyclic S8 structure. Apart of the cyclic S8 ... -
C–H Activation by Iron(III), Manganese(II) and Rhoda(III)electro Catalysis
(2020-12-15)While major progress was realized with noble transition metal catalysts, the employment of cost-effective and earth-abundant 3d metals has gained significant momentum during the last decade. As stoichiometric amounts of ... -
Iron-Catalyzed C–H/N–H Activations for Annulation of Allenes, Alkynes, and Bicyclopropylidenes
(2020-11-16)Iron-catalyzed C–H/N–H activations for the annulation of allenes, alkynes, and bicyclopropylidenes were realized by using a customizable clickable triazole amide under mild reaction conditions. The powerful iron catalysis ... -
Transition Metal-Free Catalytic Systems for the Utilization of CO2 to Achieve Valuable Chemicals
(2020-11-03)The utilization of one of the most threatening greenhouse gases regarding the climate change could help changing its reputation from a harmful waste toward a green alternative feedstock. For the afore-mentioned reason, it ... -
Late-Stage Peptide Diversification via Transition Metal-Catalyzed C─H Activation
(2020-10-13)The late-stage modification of peptide is of great value to drug discovery and medicinal chemistry. Metal catalyzed C─H activation has emerged as efficient and step-economic strategy for post-translational peptide engineering. ... -
Studies Toward Selenium-pi-Acid Catalyzed Oxidative Functionalizations of Olefinic and Acetylenic Multiple Bonds
(2020-09-24)The focus of this thesis was the oxidative functionalization of alkenes via selenium-pi-acid catalysis. In the realm of dual photoredox/selenium-pi-acid catalysis, the known methodology was expanded to the use of alcohols ... -
Site-Selectivity in Ruthenium-Catalyzed C–H and C–C Activations
(2020-09-23)During the past decades, transition metal-catalyzed C–H and C–C activation has been recognized as a powerful platform in organic synthesis to access the selective construction of new C–C and C–Het bonds. The full control ... -
Metallaelectro-Catalyzed C─H Activations by 3d Transition Metals
(2020-09-17)The functionalization of C–H bonds largely relies on organic (pseudo-)halide electrophiles as coupling partners, which results in stoichiometric quantities of undesired by-products. Therefore, to achieve better resource ... -
Entwicklung regio- und enantioselektiver Transformationen an Alkenen mittels λ3-Iodan-Reagenzien bzw. chiraler Selen-π-Säure-Katalysatoren
(2020-09-02)In this thesis three novel oxidative functionalisations of alkenes are presented. The focus lay on the one hand on the development of the first aerobic phosphatation of alkens using a dual selenium-pi-acid-photoredox ... -
Constitution and Reactivity of Palladium Ate Complexes in Cross-Coupling Reactions
(2020-02-18)Palladium-catalyzed cross-coupling reactions are among the most widely used tools for the formation of new carbon-carbon or carbon-heteroatom bonds in organic synthesis. Usually, the intermediates involved in the ... -
Sustainable Synthesis by 3d Transition Metal Electro-Catalyzed C─H Activation
(2020-01-20)During the last years, new opportunities are represented by the development of 3d transition metal-catalyzed C–H activation, with possible benefits due to the significantly lower toxicity, high natural abundance and ... -
Development of Photo-Induced C–H Activation by Copper and Ruthenium Catalysis
(2019-11-08)Within recent decades, transition metal-catalyzed C–H activation has become a valuable and versatile tool for organic synthesis. As C–H bonds are ubiquitous in organic molecules, the direct site-selective functionalization ... -
Experimental and Computational Studies on Ruthenium- and Manganese-Catalyzed C-H and C-C Activation
(2019-11-07)During the last years, transition metal-catalyzed C–H and C–C activation has emerged as a powerful tool for the selective construction of C–C and C–Het bonds. In this context, a detailed mechanistic understanding of these ... -
Selectivity Control in 3d Transition Metal-Catalyzed C–H Activation
(2019-08-23)Methods for the selective functionalization of otherwise inert C–H bonds have been recognized as a transformative tool in synthetic organic chemistry, with applications ranging from the synthesis of complex bioactive ...