Browsing Fakultät für Chemie (inkl. GAUSS) by Advisor & Referee "Zeeck, Axel Prof. Dr."
Now showing items 21-40 of 44
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One-pot, Two-step Queuing Cascades Involving a Heck Coupling, π-Allylpalladium Trapping and Diels-Alder Reaction
(2006-01-23)In the first part of this study, palladium catalyzed reactions of mono-substituted bicyclopropylidenes (66B E) with iodobenzene (67) in the presence of dienophiles 68a b have been performed. ... -
Aufbau einer HPLC-UV-ESI-MS/MS-Datenbank und ihre Anwendung im Screening arktischer und antarktischer Meeresbakterien
(2005-10-21)Microorganisms from uncommon habitats are an attractive source for chemically and biologically outstanding natural compounds, for the interaction between different species in complex living ... -
Isolierung, Strukturaufklärung und Biosynthese von Sekundärmetaboliten endophytischer Pilze aus Algen und Pflanzen mariner Habitate
(2005-10-18)The core of the present thesis is the study of endophytic fungi with regard to their production of secondary metabolites. Altogether 56 fungal strains were both chemically and biologically ... -
Isolierung und Strukturaufklärung neuer Naturstoffe aus Bakterien und endophytischen Pilzen durch chemisches Screening
(2005-09-26)The present work deals with the isolation and structure elucidation of new secondary metabolites from bacteria and endophytic fungi, found by chemical screening. The antimicrobial and ... -
Beiträge zur Biosynthese von Strobilurin A und Oudemansin A sowie Gewinnung neuer halogenierter Strobilurine durch vorläufer-dirigierte Biosynthese
(2005-09-26)The integral part of this thesis are studies of the biosynthesis of the antifungal strobilurin A as well as experiments to modify the metabolite by precurser directed biosynthesis.Earlier ... -
Untersuchungen zur Biosynthese und Aktivität ausgewählter Plecomakrolide sowie chemisches Screening von Actinomyceten
(2005-06-10)This Ph.D. thesis deals with the isolation and structure elucidation of microbial secondary metabolites and comprises studies of their biosynthesis and biological activity.The first part ... -
Dynamics of the B-A Transition of DNA Double Helices
(2005-05-20)Although the B-A transition of DNA is known for about 50 years, the dynamics of this transition has not been characterized yet. Experiments with stopped flow instrument showed that the ... -
Bioactive Secondary Metabolites from Marine and Terrestrial Bacteria: Isoquinolinequinones, Bacterial Compounds with a Novel Pharmacophor
(2005-01-17)After a chemical and biological pre-screening of bacterial extracts, 17 Streptomycetes (including eleven terrestrial and six marine-derived strains) and ten North Sea bacteria (including ... -
Allene, Dihydronaphthalenon-Derivate und andere Sekundärmetabolite aus Pilzen mariner Habitate sowie Beiträge zu deren Biosynthese
(2004-12-15)The aim of this thesis was the isolation and structure elucidation of novel natural products from marine fungi as well as studies of their biosynthesis.Twelve fungal strains from marine ... -
Towards a Total Synthesis of Mensacarcin
(2004-12-09)The work in this thesis has been concerned with attempts to develop concise synthetic routes to the natural product mensacarcin, which is a novel polyfunctionalised hexahydroanthracene ... -
Reaktionen des Bis(tert-butyl-methyl)ketazins mit Halogensilanen
(2004-10-22)This thesis refers to the synthesis of unknown acyclic und cyclic silylketazines. Reactions of monolithiated bis(tert-butyl-methyl)ketazine with chloro- and fluorosilanes lead to acyclic ... -
Darstellung bor- und phosphorhaltiger Ringe durch Reaktionen von Halogenboranen und -phosphanen mit Bis(tert.-butyl-methyl)ketazin
(2004-10-22)The first part of this thesis refers to the reactions of boroles, especially substitutions of remaining halogens and dehydrohalogenation reactions. The second part deals with similarities ... -
Synthetisch interessante Transformationen von Ring-anellierten (E,Z,E)-1,3,5-Hexatrienen
(2004-10-05)Twofold palladium-catalyzed coupling reactions (Heck reactions) of 1,2-dibromocycloalkenes with styrene or acrylates afforded 1,6-diphenyl- and 1,6-dialkoxycarbonyl-substituted ... -
Final Elucidation of the Absolute Configuration of Hormaomycin - Total Synthesis of Hormaomycin and Analogs
(2004-09-14)This work has been focused on the synthesis of hormaomycin and analogs, and prior to that, on the assignment of the absolute structure of unusual amino acids, which comprise hormaomycin, ... -
Strukturaufklärung der Phenalinolactone und Beiträge zur Biosynthese der Hexacyclinsäure
(2004-04-27)This work concentrated on biosynthetic studies as well as the isolation and structure elucidation of natural substances of streptomycetes. In line with a cooperation with the workgroup of ... -
Chemisches Screening von ausgewählten Actinomyceten sowie Strukturaufklärung von Sekundärmetaboliten aus Micromonospora sp. und Pflanzen
(2004-04-27)The core of this thesis is the study of microorganisms and plants of different sources with regard to their production of secondary metabolites.The first part deals with 35 actinomycete ... -
Reaktionen des Amino-di-<i>tert</i>-butylsilanols
(2003-11-26)In contrast to carbon chemistry in silicon chemistry a kinetic stabilization of compounds with two or three OH or NH2 groups bonded to one silicon atom is possible. The reaction of (Me3C)2Si(OH)Cl with liquid ammonia affords ... -
Metabolite aus marinen und terrestrischen Bakterien und Pilzen sowie Untersuchungen von Invertebraten der Tiefsee
(2003-07-25)In this work 24 bacterial and eight fungi strains were submitted to the chemical screening for their ability to produce secondary metabolites. 17 of the bacterial and all fungi strains were ... -
Investigation of Secondary Metabolites of North Sea Bacteria: Fermentation, Isolation, Structure Elucidation and Bioactivity
(2003-06-24)In this work 39 bacterial strains from the North Sea were submitted to the chemical and biological screening and due to the results four strains were examined thoroughly for interesting ... -
Molecular mechanisms of AMPA and kainate receptor gating and its implication in synaptic transmission
(2002-11-25)In this work we have studied the biophysical properties of AMPA and kainate receptors, which are found mainly in central synapses. AMPA receptors are thought to be tetrameric in nature. The ...