Browsing Fakultät für Chemie (inkl. GAUSS) by Referee "Koszinowski, Konrad Prof. Dr."
Now showing items 21-40 of 58
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Resource-Economical C–H Activation for Late-Stage Functionalization
(2021-07-07)Organic synthesis has traditionally relied on step-, time- and resource-intensive strategies, namely the functional group interconversion and, more recently, on cross-coupling reactions. These approaches have enabled the ... -
C–H and C–F Activation by Manganese, Nickel and Ruthenium Catalysis
(2021-04-19)The development of novel environment-friendly, step- and atom-economical methodologies is one of the main goals in organic chemistry. In this context, the direct functionalization of inert C–(Het) and C–H bonds has ... -
Ion mobility mass spectrometry as a powerful tool to analyze complex macromolecular systems
(2021-02-01)Modern applications of polymers rely on intricately tailored macromolecules exhibiting very specific properties and therefore require extensive analysis. In this context, IMMS is an immensely powerful technique since it ... -
Synthesis and reactivity of succinylthioimidazolium salts: A unified strategy for the preparation of thioethers
(2020-12-21)Sulfur is one of the main group elements on our planet with a natural abundance of (0.46±0.15)w%. In its most common allotropic form sulfur is a yellow powder and exhibits a cyclic S8 structure. Apart of the cyclic S8 ... -
C–H Activation by Iron(III), Manganese(II) and Rhoda(III)electro Catalysis
(2020-12-15)While major progress was realized with noble transition metal catalysts, the employment of cost-effective and earth-abundant 3d metals has gained significant momentum during the last decade. As stoichiometric amounts of ... -
Visible Light-Mediated Metal-Free Photocatalytic Oxidative Reactions and Cycloadditions
(2020-11-16)Currently, there is a strong demand for the development of sustainable chemistry by reducing hazardous substances and using less energy during the process. Hence, ‘Green Chemistry’ or ‘Sustainable Chemistry’ has become the ... -
Transition Metal-Free Catalytic Systems for the Utilization of CO2 to Achieve Valuable Chemicals
(2020-11-03)The utilization of one of the most threatening greenhouse gases regarding the climate change could help changing its reputation from a harmful waste toward a green alternative feedstock. For the afore-mentioned reason, it ... -
Schwingungsspektroskopische Untersuchungen zur Chiralitätserkennung und Torsionsdynamik bei Alkoholen
(2020-10-20)In this thesis different implications of molecular chirality are explored by experimental and quantum chemical methods. Discriminating interactions between molecules of different handedness, termed chirality recognition, ... -
Late-Stage Peptide Diversification via Transition Metal-Catalyzed C─H Activation
(2020-10-13)The late-stage modification of peptide is of great value to drug discovery and medicinal chemistry. Metal catalyzed C─H activation has emerged as efficient and step-economic strategy for post-translational peptide engineering. ... -
Studies Toward Selenium-pi-Acid Catalyzed Oxidative Functionalizations of Olefinic and Acetylenic Multiple Bonds
(2020-09-24)The focus of this thesis was the oxidative functionalization of alkenes via selenium-pi-acid catalysis. In the realm of dual photoredox/selenium-pi-acid catalysis, the known methodology was expanded to the use of alcohols ... -
Site-Selectivity in Ruthenium-Catalyzed C–H and C–C Activations
(2020-09-23)During the past decades, transition metal-catalyzed C–H and C–C activation has been recognized as a powerful platform in organic synthesis to access the selective construction of new C–C and C–Het bonds. The full control ... -
Entwicklung regio- und enantioselektiver Transformationen an Alkenen mittels λ3-Iodan-Reagenzien bzw. chiraler Selen-π-Säure-Katalysatoren
(2020-09-02)In this thesis three novel oxidative functionalisations of alkenes are presented. The focus lay on the one hand on the development of the first aerobic phosphatation of alkens using a dual selenium-pi-acid-photoredox ... -
Novel Cationic Sulfur Reagents and their Application in Electrophilic Group-Transfer Reactions
(2020-06-08)The two major research achievements of this work are the development of novel sulfur-based electrophilic transfer reagents based on pyridinium, as well as the extension of the reactivity of already established imidazolium ... -
Constitution and Reactivity of Palladium Ate Complexes in Cross-Coupling Reactions
(2020-02-18)Palladium-catalyzed cross-coupling reactions are among the most widely used tools for the formation of new carbon-carbon or carbon-heteroatom bonds in organic synthesis. Usually, the intermediates involved in the ... -
Sustainable Synthesis by 3d Transition Metal Electro-Catalyzed C─H Activation
(2020-01-20)During the last years, new opportunities are represented by the development of 3d transition metal-catalyzed C–H activation, with possible benefits due to the significantly lower toxicity, high natural abundance and ... -
From Copper to Gold: Identification and Characterization of Coinage-Metal Ate Complexes by ESI Mass Spectrometry and Gas-Phase Fragmentation Experiments
(2020-01-09)Organocuprates are important reagents with numerous applications in preparative organic chemistry, which has led to extensive investigations regarding their molecular composition. However, while lithium organocuprates have ... -
Theoretical high-resolution spectroscopy for reactive molecules in astrochemistry and combustion processes
(2019-12-19)Rovibrational spectroscopy is a prime tool for the indirect investigation of molecular potential energy surfaces (PES). Naturally, theoretical predictions of molecular spectra have been the focus of numerous works since ... -
Development of Photo-Induced C–H Activation by Copper and Ruthenium Catalysis
(2019-11-08)Within recent decades, transition metal-catalyzed C–H activation has become a valuable and versatile tool for organic synthesis. As C–H bonds are ubiquitous in organic molecules, the direct site-selective functionalization ... -
Experimental and Computational Studies on Ruthenium- and Manganese-Catalyzed C-H and C-C Activation
(2019-11-07)During the last years, transition metal-catalyzed C–H and C–C activation has emerged as a powerful tool for the selective construction of C–C and C–Het bonds. In this context, a detailed mechanistic understanding of these ... -
C-H Activation by Nickel and Iron Catalysis
(2019-08-08)The thesis contents methods for the selective activation and functionalization of C–H bonds, among the most abundant bonds in organic molecules. In particular, earth-abundant and cost-effective nickel and iron complexes ...