Browsing Fakultät für Chemie (inkl. GAUSS) by Title
Now showing items 318-337 of 758
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Konzeptualisierung des Themas "Nano" für den Chemieunterricht
(2016-11-23)Nanotechnology is considered as one of the 21st century’s key technologies that can be helpful in solving some of the greatest challenges of our time. Because of this technology’s distinct influence on our future, it is ... -
Kristallographische Analyse von pathologischen Kristallen, Periplasmischen dömane von ligandfreien CitA Sensor Kinasen und PDI-verwandten Chaperone
(2006-11-08)The current work reports on developing methods to elucidate crystal structure of nonmerohedrally twinned protein crystals and analysis of structures of different proteins that mediate signal ... -
Die Kristallstruktur der α-Amylase A aus dem hyperthermophilen Bakterium Thermotoga maritima MSB8
(2003-04-03)α-Amylases catalyze the hydrolytic cleavage of α-glycosidic linkages in starch, glycogen and a number of other related compounds and play an important role in the metabolism of plants, ... -
Kristallstrukturen der Aldose-Reduktase und der C2A-Domäne von Rabphilin3A sowie Überprüfungen neuer Restraints.
(2006-11-06)The high resolution (0.82 Å) structure of Aldose Reductase (an enzyme implicated in the polyol pathway) is presented. The aim of the work was a careful inspection of the model with particular ... -
Kristallstrukturen der C2B-Domäne von Rabphilin-3A und der PP2C-ähnlichen Phosphatase tPphA von Thermosynechococcus elongatus BP-1
(2006-09-28)The first part of this thesis deals with the x-ray crystal structure of the C2B domain of Rabphilin-3A, which includes part of the linker region between the C2A and C2B domain. The second ... -
Kristallstrukturuntersuchungen zum Katalyse- und Regulationsmechanismus der Tyrosin-regulierten 3-Deoxy-D-arabino-Heptulosonat-7-Phosphat-Synthase aus Saccharomyces cerevisiae
(2003-08-06)The ability to synthesize the aromatic amino acids tyrosine, phenylalanine and tryptophan is confined to prokaryotes, yeast, algae and plants. The first common step in biosynthesis for ... -
Kupfer- und palladiumkatalysierte N H- und C H-Bindungsfunktionalisierungen zur effizienten Synthese von Heterocyclen
(2011-05-20)Several approaches for the synthesis of substituted indoles, (benz)oxazoles and oxazolines using copper- and palladium-catalyzed reactions are examined. A copper-catalyzed synthesis of ... -
Laserspektroskopische Untersuchungen zur Dynamik von ionischen Flüssigkeiten mit Hilfe molekularer Sonden
(2011-08-24)Ionic liquids have been studied by transient absorption spectroscopy. Relaxation processes after photo excitation of molecular probes were used as an indicator to study the microscopic ... -
Late-Stage Peptide Diversification via Transition Metal-Catalyzed C─H Activation
(2020-10-13)The late-stage modification of peptide is of great value to drug discovery and medicinal chemistry. Metal catalyzed C─H activation has emerged as efficient and step-economic strategy for post-translational peptide engineering. ... -
Late-Stage Peptide Functionalization by Ruthenium-Catalyzed C H Arylations and Alkylations
(2018-11-08)The thesis contents methods for the selective activation and functionalization of C–H bonds of the C2 position of a tryptophan moiety incorporated into peptides. Palladium-catalyzed C-H arylation reactions applying ... -
Late-Stage Peptide Functionalization by Transition Metal-free and Palladium-Catalyzed C–H Arylations
(2022-03-31)The focus of this thesis was set on the late-stage modification of peptides through transition metal-free and palladium-catalyzed C–H arylations. At first, the scope of the transition metal-free C2-arylation of the ... -
Lateral Organization and Thermodynamics of Coiled-coil Lipopeptides - Implications for Docking and Fusion Efficiency
(2013-01-24)Specific cellular membrane interaction is a crucial point in nature as it facilitates key processes like cell-cell communication or membrane fusion. The latter one is highly controlled frequently mediated by the superfamily ... -
Laterale Organisation von Shiga Toxin gebunden an Gb3-haltige Modellmembranen
(2009-07-15)The aim of this study was to elucidate lateral organization of bound STxB (Shiga Toxin, B-subunit) and the reorganization of lipids upon protein binding by means of high-resolution scanning ... -
Lichtinduzierte Primärprozesse in reversibel photoschaltbaren fluoreszierenden Proteinen: Zeitaufgelöste Spektroskopie von Padron0.9 und rsFastLime
(2015-05-18)Within this project, the photodynamics of the reversibly switchable fluorescent proteins Padron0.9 and rsFastLime after photoexcitation were investigated. Cis/trans-isomerization of the chromophore is an essential element ... -
Ligand Design of Sulfur-Centered Chelates
(2010-04-21)Owing to their electrophilic sulfur atom nearly any nucleophile can be added to the sulfurimides, yielding a variety of diimidosulfinates and triimidosulfonates. This trait opens up a lot ... -
Liganden mit N/S-Donorsets in der Münzmetallchemie: Modellkomplexe für Methanobactin und multinukleare, lumineszierende Pyrazolat-Komplexe
(2013-03-12)The synthesis and characterization of pyrazolate and oxazolone ligands with attached thioether functions is described. These ligands were used either to synthesize copper(I) complexes as model complex for the methanobactin ... -
Light-Control of Biomimetic and Bioactive Molecules
(2025-08-19)Light-controlled molecules enable precise spatial and temporal regulation of biological activity, supporting both fundamental research and the development of new therapeutics. In this work, photolipids and photocaged ... -
Lithiumamide, -hydrazonide und -ketazide als Bausteine acyclischer, cyclischer und spirocyclischer Bor-, Phosphor- und Siliciumverbindungen sowie monomerer und dimerer Amino-imino-borene
(2009-02-09)Flurorosilylhydrazones are obtained from the reaction of lithiated hydrazones with fluorosilanes. On subsequent reaction with tert-butyllithium, cyclization takes place, to give ... -
Live Cell STED Microscopy using Genetically Encoded Markers
(2009-08-05)Far-field fluorescence microscopy is a tool of outstanding importance in the biological sciences, due to its non-invasiveness especially for the investigation of living cells, tissue and ... -
Local Orbital Analysis of Electronic Correlation in Molecular Systems
(2023-12-12)This thesis explores chemical problems through a combination of experiments and theoretical studies, leveraging advancements in computer hardware and quantum chemical algorithms to tackle challenges beyond the scope of ...