Upon myocardial infarction, the natural healing response triggers the fibroblast-to-myofibroblast transition (FMT). Through this process, fibroblasts acquire a myofibroblast phenotype by which they present increased mobility, ...

The quadrupolar nature of approximately 75% of all nuclei is often perceived as troubling for nuclear magnetic resonance (NMR) spectroscopists, since the quadrupolar interaction between the nuclear quadrupole moment and ...

The advent of new synthetic strategies has enriched the synthetic organic chemistry to access molecules with tremendous complexity. In this context, transition metal-catalyzed C−H activation has emerged as a powerful tool ...

Activation, splitting and fixation of dinitrogen remains one of the most challenging reactions in coordination chemistry. In this thesis, osmium and rhenium complexes based on a PNP pincer ligand are synthesized and ...

In der vorliegenden Arbeit werden Röntgenstrukturuntersuchungen an Glycopeptiden vorgenommen. Dabei gliedert sich die Dissertation in zwei Teile. Der erste Teil beschäftigt sich ...

Transition metal-catalyzed cross-coupling reaction as one of the greatest chemical innovations of 20th century has to utilize stoichiometric amounts of prefunctionalized reagents. In comparison, the transition metal-catalyzed ...

Ruthenium catalyzed C-N, C-O and C-C formation is achieved by C-H activation. access to primary aminoketones leds to synthetic synthons for different heterocycles. removable and reusability was shown first time in C-O bond ...

The thesis contents methods for the ruthenium- and cobalt catalyzed C-H activation of arenes. Ruthenium(II) catalysis was used to alkenylate arylacetamides using acrylates or alkynes. Further, ruthenium-catalyzed C-H ...

Catalytic C−H functionalization has emerged as an economically-attractive and environmentally-benign alternative to conventional cross-coupling approaches. Thus, major efforts have been made on transformations of inert C–H ...

The main focus of this work was the development of new methodologies for the efficient and step-economical synthesis of biaryls cores by direct arylation through direct C–H bond cleavage. In this aim, the first ruthenium-catalyzed ...