Browsing Fakultät für Chemie (inkl. GAUSS) by Title
Now showing items 574-593 of 763
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Sticky triangles: New tools for experimental phasing of biological macromolecules
(2010-12-07)X-ray crystallography is the prime method for the elucidation of three-dimensional molecular structures. It enables the structure determination of biological macromolecules such as proteins ... -
Stoßwellenuntersuchungen und Modellierung der Pyrolyse von Pentafluorethan und 2-H-Heptafluorpropan
(2014-02-20)The pyrolysis of C2HF5 and C3HF7 have been studied in shock waves by monitoring die UV-absorption of CF2 at 248nm and temperatures in the range of 1400 - 2000 K. Ar was used as bath gas with concentrations in the range ... -
Structural analysis of organometallic deprotonation agents and computational studies on formally hypervalent molecules
(2010-10-22)The following thesis targets two topics. The first one deals with the synthesis and crystallization of reactive organometallic deprotonation agents and important metalated intermediates ... -
Structure and Mechanics of Membrane-bound Vimentin Filaments and Networks under Strain
(2022-12-16)The shape and mechanical properties of eukaryotic cells are determined by the cytoskeleton, composed of actin filaments, microtubules and intermediate filaments (IFs). Among these, IFs are considered to be the main ... -
Structure determination of peptides with antimicrobial action
(2004-07-28)Peptide antibiotics belonging to three different families were investigated using X-ray crystallography. The peptaibol antibiotics cephaibol A, B and C gave well-diffracting crystals and ... -
Structure, Dynamics and Phase Behaviors of Cationic Micellar Solutions:
(2006-12-11)In this work, the combination of Raman spectroscopy and Small Angle Neutron scattering (SANS) have been used for the first time, to understand the aggregational behavior of micelles ... -
Structure, Mechanism and Inhibition of the human Glutaminyl Cyclase
(2017-03-24)The mammalian zinc-dependent enzyme glutaminyl cyclase (QC, EC 2.3.2.5) belongs to the family of transferases and plays a crucial role in hormone maturation by cyclizing irreversibly N-terminal glutamines post-translationally ... -
Structure-Property Correlations in Luminescent Anthracene Derivatives
(2022-02-17)This thesis aims to investigate the structure-property relationship of luminescent Anthracene derivatives. For this purpose, the Anthracene fluorophore was functionalized in various positions and with different substituents. ... -
Struktur und Biosynthese von Collinolacton aus Streptomyces sp. und Beiträge zum Screening neuer Wirkstoffe
(2006-10-16)The cyclodecatrien collinolactone is a new microbial natural product from Streptomyces sp. Gö 40/10 and represents a hitherto unknown chemical class of substances. The structure elucidation ... -
Struktur und Biosynthese von Spirodionsäure und Kirromycin aus Streptomyces sp.
(2009-04-09)The first project is about the investigation of the biosynthesis of the novel microbial metabolite spirodionic acid and its absolute stereoconfiguration. Within the scope of these biosynthetic ... -
Die Strukturabhängigkeit der Festkörperfluoreszenz bei Phosphanylanthracenen
(2008-05-30)Four major aims have been pursued in the course of this thesis: 1. Synthesis and charactarization of 9-bromo-10-phosphanylanthracenes. 2. Investigation of the relationship between crystal ... -
Strukturaufkälrung von Natrium-Solvens-Clustern durch IR-anregungsmodulierte Photoionisatiosnspektroskopie
(2012-10-09)In this work the method of IR-excitation modulated photoionisation mass spectroscopy is introduced. As a preparation, it is shown in a photoionization study that at least two classes of isomers exist for larger sodium doped ... -
Strukturaufklärung der Phenalinolactone und Beiträge zur Biosynthese der Hexacyclinsäure
(2004-04-27)This work concentrated on biosynthetic studies as well as the isolation and structure elucidation of natural substances of streptomycetes. In line with a cooperation with the workgroup of ... -
Strukturdynamik wasserhaltiger Aggregate in Überschallexpansionen
(2014-07-08)Isolated molecular clusters can be investigated by Fourier transform infrared spectroscopy of supersonic expansions. It is shown how multi slit nozzles of different geometries can be used both for the elucidation of the ... -
Strukturelle und funktionelle Charakterisierung von dem mitochondrialen Membranprotein Menschlicher Spannungsabhängiger Anionen Kanal (HVDAC) und dem Membranprotein bindenden Conotoxin Conkunitzin-S1 mit Flüssigphasen NMR
(2007-08-02)This thesis sheds light on the mode of action of membrane proteins and their ligands. Two model systems were chosen: the membrane protein was the human voltage dependent anion channel (HVDAC) ... -
Strukturelle Untersuchungen an Varianten des Ecballium elaterium Trypsin Inhibitors-II (EETI-II)
(2001-08-15)The inhibitor cystine-knot family is composed of a large number of small, around 30 amino acids long proteins, that show a diversity of inhibitory functions. The characteristic structural ... -
Strukturuntersuchungen zum Reaktionsmechanismus an der Alkylsulfatase AtsK aus Pseudomonas putida S-313
(2004-01-21)The alkylsulfatase AtsK is one of several proteins expressed by Pseudomonas putida under sulfate starvation, which enable the organism to use various organic sulfonates and sulfate esters ... -
Studien zur Ansamitocin-Biosynthese sowie Sekundärstoffproduktion durch mikrobielle Interaktion
(2009-06-23)This thesis is structured in four separate sections. The main part is about biosynthetic investigations of Ansamitocin, a high-potent antitumor agent belonging to the family of the maytansins. ... -
Studien zur oxidativen Funktionalisierung von Alkenen mittels Selen-pi-Säure-Katalyse
(2019-01-24)The application of diselenides as catalysts for the oxidative functionalization of alkenes via selenium-pi-acid catalysis was researched. Besides a method for the diselenide-catalyzed formation of indoles relying on NFSI ... -
Studies on the Crystallographic Phasing of Proteins: Substructure Validation and MAD-phased Electron Density Maps at Atomic Resolution
(2004-01-09)X-ray crystallography is one of the most important methods in structural biology. The availability of heavy atom derivatives of proteins facilitates the application of the crystallographic ...