Browsing Fakultät für Chemie (inkl. GAUSS) by Advisor & Referee "Meijere, Armin de Prof. Dr."
Now showing items 1-20 of 34
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Photoaktivierungsfähige Rhodamine als Bio-Calcium-Sensoren und Markierungen für Tetracystein-Tags in Proteinen
(2011-02-25)New xanthenes with differently located azacrown ether residues were conceived and synthesized, and their spectral as well as calcium-binding properties evaluated. Three derivatives with an ... -
Novel Syntheses of Nitrogen Heterocycles from Isocyanides
(2010-02-22)The direct copper(I)-catalyzed synthesis of 2,3,4-trisubstituted and 3,4-disubstituted pyrroles from substituted methyl isocyanides and acceptor-substituted acetylenes as well as the newly ... -
Fluorescent and Photochromic Fluorescent Compounds for Applications in Optical Nanoscopy
(2009-11-05)New 1,2-bis(3-thienyl)perfluorocyclopentenes, which can be reversibly switched between colorless and colored forms using near-UV (375 nm) or visible light, were synthesized, and their ... -
Totalsynthese der Mansouramycine A-E aus Streptomyces sp. und Rhodium-katalysierte 1,2-Additionen an cyclische Enone
(2009-10-02)The following thesis is divided into two sections. The first part deals with the total synthesis of Mansouramycin A-E. The second part shows a new high enantioselective rhodium catalyzed ... -
Synthese und Anwendung eines radioaktiven Photoaffinitätslabels zur Wirkortbestimmung von Naturstoffen sowie Beiträge zur Totalsynthese des Collinolactons
(2009-05-05)Starting form Dibromobenzene, an effective synthesis of a radioactive labeled photoaffinity-probe was realized. By using a double-silylated diaziridine as an intermediate the first direct ... -
Synthesis of Diverse Polyfunctional Amides as Precursors to Potentially Interesting Peptidomimetics
(2008-10-22)First chapter is dedicated to the applying of the Ugi multicomponent reaction for the synthesis of the compound containing small ring systems such as cyclopropane and its structure ... -
Catalytic Insertion Reactions into the Cyclopropane Ring Syntheses of Various Belactosin C Congeners and Analogues
(2008-09-17)Catalytic insertion reactions of various cyclic (4-phenyl-1,2,4-triazoline-3,5-dione, PTAD) and acyclic (azobenzene, ethyl phenyldiazenecarboxylate and diisopropyl azodicarboxylate) diazene ... -
Total Synthesis of Various Hormaomycin Analogues with Modified Amino Acid Residues
(2008-07-28)Hormaomycin 1 and its all-peptide aza-analogue 53 were synthesized in quantities of 39 and 34 mg respectively, using the protocol developed by B. Zlatopolskiy, to have enough material for ... -
Die Iromycine und das Collinolacton: Synthese mikrobieller Naturstoffe aus Streptomyces sp.
(2007-10-19)In this work the total synthesis of two natural products - iromycins A and collinolacton was studied. The total synthesis of iromycin A, a microbial metabolite combining a novel structure ... -
Beiträge zur Biosynthese der antiparasitären Naturstoffe Hormaomycin und Borrelidin sowie Strukturaufklärung von Sekundärmetaboliten aus Actinomyceten
(2006-11-29)The core of the present thesis deals with studies of the natural products hormaomycin and borrelidin. Furthermore the isolation and structure elucidation of secondary metabolites from ... -
Synthese und Untersuchung von Nukleobasen-funktionalisierten Peptiden
(2006-08-17)This thesis dealt with the properties of nucleobase-functionalized peptides. Influences of aromatic sidechains on the structure and aggreagation of peptides could be shown. The knowledge ... -
One-pot, Two-step Queuing Cascades Involving a Heck Coupling, π-Allylpalladium Trapping and Diels-Alder Reaction
(2006-01-23)In the first part of this study, palladium catalyzed reactions of mono-substituted bicyclopropylidenes (66B E) with iodobenzene (67) in the presence of dienophiles 68a b have been performed. ... -
Synthesis of New Spirocyclopropanated beta-Lactams and Their Application as Building Blocks for beta-Amino Acid Peptides
(2005-12-12)Several differently substituted monocyclic 3-spirocyclopropanated β-lactams, formally derived from α-cyclopropyl-modified β-alanine, have been prepared through the rearrangement of ... -
Ein Baukastensystem zum universellen Aufbau kleiner rigidifizierter Peptidomimetika und spirocyclopropanierter Wirkstoffanaloga
(2005-10-28)In contrast to the various synthetic accesses to biologically active peptidomimetics developed by other groups, we start from a single readily available class of building blocks. As in a ... -
New Applications of Methyl 2-Chloro-2-cyclopropylideneacetate Towards the Synthesis of Biologically Important Heterocycles
(2005-09-23)The work in this thesis starts with the advanced synthesis of methyl 2-chloro- and 2-bromo-2-cyclopropyledeneacetate (4-Me and 5). The cyclopropanol derivative (31) obtained by Kulinkovich ... -
Development of Viable Synthetic Approaches to Highly Functionalized Small Ring Systems - Synthesis of Novel Cyclopropylacrylates as Monomers for Low-Shrinkage Polymer-Composites
(2005-07-13)Twenty-eight new alkyl 2-cyclopropylacrylates with various substitution patterns were synthesized from readily available precursors applying appropriately modified variants of standard transformations or newly developed ... -
β-Aminosubstituted α,β-Unsaturated Fischer Carbene Complexes as Precursors for Complex Oligocyclic Molecules - Basics and Applications
(2005-01-24)Under the optimized conditions, a wide range of β-Aminosubstituted α,β-unsaturated Fischer carbene complexes were easily prepared in a four-step one-pot operation. Reaction of Fischer ... -
Versuche zur Erzeugung des Pentacyclopropylcyclopentadienyl-Kations, und Synthese von Cyclopropylierten Oligoenen, Carbo- und Heterocyclen
(2004-12-27)The objective of this dissertation on the one hand was to generate the pentacyclopropylcyclopentadienyl cation under stable cation conditions and its characterization by low-temperature ... -
Synthesis of Potentially Biologically Active Cyclopropane- and Spirocyclopropane-annelated Oligoazaheterocycles
(2004-11-23)In this work the synthesis of new cyclopropane- and spirocyclopropane-annelated heterocyclic compounds containing nitrogen has been reported. The Ti-mediated intramolecular reductive ... -
Intramolekulare Titan-vermittelte Aminocyclopropanierung als Zugang zu N-Benzyl-4-alkyl-2-azabicyclo[3.1.0]hexanen - Synthese von tri- und tetrasubstituierten Alkenen durch Palladium-katalysierte Kreuzkupplung von Alkin-Titan-Komplexen
(2004-11-02)Alkene- and alkadiene-substituted formamides were intramolecularly amino-cyclopropanated. Furthermore, titanium-complexes of unsaturated compounds were cross-coupled with severa bromobenzenes via ...