Browsing Fakultät für Chemie (inkl. GAUSS) by Advisor & Referee "Thomas, Franziska Dr."
Now showing items 1-12 of 12
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Revealing atomic resolution structural insights into membrane proteins in near-native environments by proton detected solid-state NMR
(2021-05-18)Membrane proteins are an essential part of any living organism. They are cellular switches that trigger metabolic cascades regulating the cell metabolism, including cell division, gene expression and others functions as ... -
Investigations towards the design, synthesis and application of new sulfur-based transfer reagents
(2019-06-20)New dibenzothiophenium-based alkynylation reagents were prepared and their versatile reactivity was demonstrated in reactions with benchmark C-, S-, N- and P-nucleophiles. Straightforward experiments applying 13C-labeled ... -
Synthesis and Characterization of Polydentate C3 Symmetric Ligand Systems in Metal Coordination
(2019-06-03)Tripodal ligand systems are of key interest in the synthesis of new and promising metal complexes since their tridentate coordination sphere can be used to generate a multitude of different bonding motifs with a suitable ... -
Organoferrate als Intermediate in Eisen-Katalysierten Kreuzkupplungsreaktionen
(2019-05-24)In the context of this work a combination of ESI mass spectrometry, mößbauer spectroscopy and electrical conductometry was used to identify and characterize a large number of organoferrates. These anionic species, which ... -
Late-Stage Peptide Functionalization by Ruthenium-Catalyzed C H Arylations and Alkylations
(2018-11-08)The thesis contents methods for the selective activation and functionalization of C–H bonds of the C2 position of a tryptophan moiety incorporated into peptides. Palladium-catalyzed C-H arylation reactions applying ... -
Synthesis, Structure and Applications of Cationic Phosphonites
(2018-11-07)Phosphorus based ligands are a hugely important class of ligands for homogenous catalysis, owing to the easy fine-tuneability of their steric and electronic properties. In α-cationic phosphines, the incorporation of a ... -
Aerobic Ruthenium-Catalyzed C–H Activations
(2018-08-31)Within the last decades C–H activation processes have evolved from a promising concept to a powerful class of reactions for the construction of organic molecules, especially pharmaceutically active compounds. Within this ... -
Nitric Oxide Reactivity and Unusual Redox Properties of Biomimetic Iron-Sulfur Clusters with Alternative Cluster Ligands
(2018-05-02)This work describes the nitrosylation of biomimetic [2Fe–2S] clusters with phenylbis(benzimidazol-2-yl)methane or benzimidazolthiophenol ligands in different iron oxidation states and ligand protonation states. Mixed-valent ... -
Hybrids of SNARE Transmembrane Domains and Artificial Recognition Motifs as Membrane Fusion Inducing Model Peptides
(2018-03-13)Protein mediated fusion of membranes is a crucial biological process. For instance, SNARE (soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein receptor) proteins are involved in neuronal exocytosis. However, ... -
Dynamics, Intermolecular Interactions, and Organization of Transmembrane β-Peptides
(2018-02-01)Cellular membranes contain a vast variety of proteins, which are practically required for every vital mechanism, such as selective transportation of ions and organic molecules, cell-cell recognition and signal transduction.[1] ... -
C-H and C-C Activation by Cobalt and Ruthenium Catalysis
(2017-12-18)The thesis contents methods for the selective activation and functionalization of C–H and C–C bonds, among the most abundant bonds in organic molecules. In particular, earth-abundant and cost-effective cobalt complexes ... -
Design, Synthesis and Applications of new cationic ligands of the 15th main group elements
(2017-12-08)The dissertation focuses on the development of new cationic phosphines and their applications in transition metal catalyses. In pi-acid catalysis they proved their superiority in comparison with state of the art ligand ...