Browsing Fakultät für Chemie (inkl. GAUSS) by Advisor "Meijere, Armin de Prof. Dr."
Now showing items 1-20 of 28
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Ein Baukastensystem zum universellen Aufbau kleiner rigidifizierter Peptidomimetika und spirocyclopropanierter Wirkstoffanaloga
(2005-10-28)In contrast to the various synthetic accesses to biologically active peptidomimetics developed by other groups, we start from a single readily available class of building blocks. As in a ... -
Catalytic Insertion Reactions into the Cyclopropane Ring Syntheses of Various Belactosin C Congeners and Analogues
(2008-09-17)Catalytic insertion reactions of various cyclic (4-phenyl-1,2,4-triazoline-3,5-dione, PTAD) and acyclic (azobenzene, ethyl phenyldiazenecarboxylate and diisopropyl azodicarboxylate) diazene ... -
Design und Synthese neuer flüssigkristalliner Substanzen mit zentraler Bicyclo[3.1.0]hexaneinheit
(2003-07-10)Starting from the first observations of the phenomenon of liquid crystallinity by Reinitzer in 1888 and by Lehmann in 1889, the design and preparation of molecules possessing liquid crystalline ... -
Development of Viable Synthetic Approaches to Highly Functionalized Small Ring Systems - Synthesis of Novel Cyclopropylacrylates as Monomers for Low-Shrinkage Polymer-Composites
(2005-07-13)Twenty-eight new alkyl 2-cyclopropylacrylates with various substitution patterns were synthesized from readily available precursors applying appropriately modified variants of standard transformations or newly developed ... -
Final Elucidation of the Absolute Configuration of Hormaomycin - Total Synthesis of Hormaomycin and Analogs
(2004-09-14)This work has been focused on the synthesis of hormaomycin and analogs, and prior to that, on the assignment of the absolute structure of unusual amino acids, which comprise hormaomycin, ... -
Fluorescent and Photochromic Fluorescent Compounds for Applications in Optical Nanoscopy
(2009-11-05)New 1,2-bis(3-thienyl)perfluorocyclopentenes, which can be reversibly switched between colorless and colored forms using near-UV (375 nm) or visible light, were synthesized, and their ... -
Intramolekulare Titan-vermittelte Aminocyclopropanierung als Zugang zu N-Benzyl-4-alkyl-2-azabicyclo[3.1.0]hexanen - Synthese von tri- und tetrasubstituierten Alkenen durch Palladium-katalysierte Kreuzkupplung von Alkin-Titan-Komplexen
(2004-11-02)Alkene- and alkadiene-substituted formamides were intramolecularly amino-cyclopropanated. Furthermore, titanium-complexes of unsaturated compounds were cross-coupled with severa bromobenzenes via ... -
Die Iromycine und das Collinolacton: Synthese mikrobieller Naturstoffe aus Streptomyces sp.
(2007-10-19)In this work the total synthesis of two natural products - iromycins A and collinolacton was studied. The total synthesis of iromycin A, a microbial metabolite combining a novel structure ... -
Neue Übergangsmetall-vermittelte Reaktionen zum effizienten Aufbau cyclopropanhaltiger Oligocyclen
(2004-10-20)The objective of this thesis is the development of new transition metal-mediated reactions for the construction of cyclopropanated oligocycles. In the first part of the thesis, the ... -
New Applications of Methyl 2-Chloro-2-cyclopropylideneacetate Towards the Synthesis of Biologically Important Heterocycles
(2005-09-23)The work in this thesis starts with the advanced synthesis of methyl 2-chloro- and 2-bromo-2-cyclopropyledeneacetate (4-Me and 5). The cyclopropanol derivative (31) obtained by Kulinkovich ... -
Novel Syntheses of Nitrogen Heterocycles from Isocyanides
(2010-02-22)The direct copper(I)-catalyzed synthesis of 2,3,4-trisubstituted and 3,4-disubstituted pyrroles from substituted methyl isocyanides and acceptor-substituted acetylenes as well as the newly ... -
One-pot, Two-step Queuing Cascades Involving a Heck Coupling, π-Allylpalladium Trapping and Diels-Alder Reaction
(2006-01-23)In the first part of this study, palladium catalyzed reactions of mono-substituted bicyclopropylidenes (66B E) with iodobenzene (67) in the presence of dienophiles 68a b have been performed. ... -
Palladium-Catalyzed Oligocyclizations of Some 2-Bromotetradec-1-ene-7,13-diynes Under Heck Reaction Conditions
(2003-12-16)Synthesis of different substituted 2-bromotetradec-1-ene-7,13-diyne precursors can be easily achieved by using 1,7-octadiyne. The cyclization outcome of these precursors depends on the type ... -
Palladium-katalysierte Domino-Reaktionen zum Aufbau bi- und tricyclischer Systeme
(2001-08-30)Domino-processes between palladium-catalyzed cross-coupling reactions - Heck-reaction and Enyne-Cycloisomerization - followed by Diels-Alder-reactions have been studied. The ... -
Palladium-katalysierte Kreuzkupplungen zu 1,2-Dialkenylcycloalkenen: Ausgangsstoffe zur Synthese vielfältiger cyclischer Kohlenstoffgerüste
(2001-10-24)Palladium-catalyzed coupling reactions of 1,2-dibromocycloalkenes with styrene and acrylates afforded 1,6-diphenyl- and 1,6-bisalkoxycarbonyl-substituted (E,Z,E)-1,3,5-hexatrienes ... -
Photoaktivierungsfähige Rhodamine als Bio-Calcium-Sensoren und Markierungen für Tetracystein-Tags in Proteinen
(2011-02-25)New xanthenes with differently located azacrown ether residues were conceived and synthesized, and their spectral as well as calcium-binding properties evaluated. Three derivatives with an ... -
Sesquiterpen-Analoga aus b-Dimethyamino-substituierten a,b-ungasättigten Fischer-Carbenkomplexen
(2004-04-26)Alkines undergo in Pyridine as a solvent one formal [3 + 2]-addition with aminocarben-Complexes and gives protected high reactive cyclopentadienones, which can be used for building of ... -
Synthese und Anwendung eines radioaktiven Photoaffinitätslabels zur Wirkortbestimmung von Naturstoffen sowie Beiträge zur Totalsynthese des Collinolactons
(2009-05-05)Starting form Dibromobenzene, an effective synthesis of a radioactive labeled photoaffinity-probe was realized. By using a double-silylated diaziridine as an intermediate the first direct ...