Browsing Fakultät für Chemie (inkl. GAUSS) by Referee "Ackermann, Lutz Prof. Dr."
Now showing items 1-20 of 81
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A. Asymmetrische Organokatalyse mit kleinen Peptiden und neuen bifunktionellen organischen Verbindungen. B. Ansätze zur asymmetrischen Produktkatalyse und zur Synthese der Naturstoffhybride
(2007-07-24)The structure/activity relationship for some (S)-histidine-based dipeptide catalysts in direct aldol reactions have been examined. The reactivities and stereoselectivities are shown to be ... -
Aerobic Ruthenium-Catalyzed C–H Activations
(2018-08-31)Within the last decades C–H activation processes have evolved from a promising concept to a powerful class of reactions for the construction of organic molecules, especially pharmaceutically active compounds. Within this ... -
Application of Asymmetric Gold-Catalyzed Hydroarylation in the Enantioselective Synthesis of Helicenes
(2022-04-07)A novel family of electron deficient, α-cationic ligands was synthesized, combining a chiral TADDOL-backbone with an electron withdrawing 1,2,3-triazolium moiety. Coordination to Au(I) gave the respective catalysts. Both ... -
C-H Activation by Nickel and Iron Catalysis
(2019-08-08)The thesis contents methods for the selective activation and functionalization of C–H bonds, among the most abundant bonds in organic molecules. In particular, earth-abundant and cost-effective nickel and iron complexes ... -
C-H Activation for Sustainable Synthesis: Base Metal- and Electro-Catalysis
(2018-08-07)In the recent decades, metal-catalyzed C-H activation greatly expanded the available tools for the sustainable synthesis of bioactive molecules and organic materials. Within this thesis, new synthetic transformations based ... -
C-H and C-C Activation by Cobalt and Ruthenium Catalysis
(2017-12-18)The thesis contents methods for the selective activation and functionalization of C–H and C–C bonds, among the most abundant bonds in organic molecules. In particular, earth-abundant and cost-effective cobalt complexes ... -
Carboxylate-Assisted Ruthenium(II)-Catalyzed C-H Alkylation and Alkenylation
(2015-10-30)Carboxylate-assisted ruthenium(II)-catalyzed C-H alkylation and alkenylation by triazole assistance and the efficient synthesis of isoindolinones -
Carboxylate-Assisted Ruthenium-Catalyzed C-H Bond meta-Alkylations and Oxidative Annulations
(2013-03-26)Site-selective ruthenium-catalyzed C-H bond functionalization was achieved under carboxylate-assistance. Direct ortho- and meta-alkylations on various arenes with unactivated alkyl halides has been accomplished and ... -
Carboxylate-Assisted Ruthenium-Catalyzed Direct C-H Bond Functionalizations
(2014-03-03)Ruthenium-catalyzed direct C–H bond functionalizations was shown to be an attractive approach for the development of sustainable chemical processes. The significant rate acceleration of cycloruthenations by carboxylates ... -
Catalytic syntheses and copper- or ruthenium-catalyzed direct C H bond arylations of (hetero)arenes
(2011-08-15)The work presented in this thesis represents recent advances in late-transition metal catalyzed cross-coupling reactions and direct arylations. The results described in section 3.1 focus ... -
Charakterisierung von Intermediaten in Cobalt-vermittelten Reaktionen
(2019-04-03)Homogeneous catalysis is from outstanding importance for modern chemical synthesis. In addition to palladium- and nickel-based catalyst systems, which are well established for a long time, also cobalt-based catalysts are ... -
Chelation-Assisted C–H Activation by Ruthenium and Osmium Catalysts and Recyclable Hybrid Catalysts
(2021-10-25)Since hydrocarbons are omnipresent structural units in organic compounds, the utilization of C–H bonds of hydrocarbons has great potential. Thereby, organic chemists have had utmost interests in the transformation of ... -
Chemically- and photo-convertible dyes for fluorescence detection of biomolecules
(2024-01-24)Further progress in fluorescence microscopy and nanoscopy depends, among other factors, on the ease of detection, analysis, and selective imaging of bioconjugates prepared from fluorescent dyes with reactive groups and ... -
Cobalt- and Nickel-Catalyzed Functionalization of Unactivated C–Hal, C–O and C–H Bonds
(2013-11-20)First row transition-metal-catalyzed C–C/C–N bond formations through the functionalization of unactivated C–Hal, C–O and C–H bonds have been developed. The inexpensive nickel and cobalt complexes were introduced to facilitate ... -
Constitution and Reactivity of Palladium Ate Complexes in Cross-Coupling Reactions
(2020-02-18)Palladium-catalyzed cross-coupling reactions are among the most widely used tools for the formation of new carbon-carbon or carbon-heteroatom bonds in organic synthesis. Usually, the intermediates involved in the ... -
C–H Activation by Ruthenium(II), Cobalt(III) and Manganese(I) Catalysis
(2017-07-07)C–H functionalizations have expanded the toolbox of organic chemistry and found widespread applications in the synthesis of complex and bioactive molecules. Within this thesis, several new synthetic transformations by ... -
C–H Activation via Iridium and Rhodium Electrocatalysis and Undirected Electrochemical Fluorination
(2022-06-24)In past decades, transition metal-catalyzed C–H activation has emerged as an increasingly viable toolbox for the step- and atom economic formation of C–C and C–Het bonds. However, oxidative C–H transformations heavily rely ... -
C–H and C–F Activation by Manganese, Nickel and Ruthenium Catalysis
(2021-04-19)The development of novel environment-friendly, step- and atom-economical methodologies is one of the main goals in organic chemistry. In this context, the direct functionalization of inert C–(Het) and C–H bonds has ... -
C−H Alkylations and Alkynylations Using Ruthenium, Nickel and Manganese Complexes
(2017-10-17)Transition metal-catalyzed C–H functionalizations have recently emerged as a reliable tool for the efficient chemo- and site-selective construction of C–C and C–Het bonds, which is of major importance for the preparation ... -
Design and synthesis of multifunctional ligands to study and prevent aggregation processes in Amyotrophic Lateral Sclerosis proteins
(2021-02-22)Amyotrophic lateral sclerosis (ALS) is an incurable lethal disease that affects motor neurons and its heterogeneity is reflected in various mutations among the sporadic ALS (sALS) and familial ALS (fALS) disease types. ...