Browsing Fakultät für Chemie (inkl. GAUSS) by Referee "Thomas, Franziska Prof. Dr."
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Design and synthesis of small organic molecules to stabilize ALS-associated SOD1 mutants
(2021-06-25)Amyotrophic Lateral Sclerosis is a globally occurring neurodegenerative disease with serious implications for the patient’s life as well as imposing a heavy economic burden both on the affected individuals and society. Due ... -
Templat-vermittelte Synthese zyklischer Peptide an programmierten Coiled-Coil-Gerüsten
(2022-12-12)In recent years, macrocyclic peptides have experienced a renaissance in research. Due to their restricted conformation, they have a high substrate specificity and, relative to their size, a large surface area. This is ... -
Untersuchungen zur Aggregation des ALS-relevanten TDP-43(307-347)
(2022-12-12)Amyotrophic lateral sclerosis (ALS) is a fatal, multicausal, neurodegenerative disease for which there is so far no cure. Abnormal cytoplasmic aggregates of TDP-43, a multifunctional RNA-binding protein, are a pathological ...