Fakultät für Chemie (inkl. GAUSS)
Recent Submissions
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Synthesis of Pyrrolo[1,2-c]pyrimidine-1-ylidenes: Coordination Chemistry and Application as Ancillary Ligands for Metal Catalysis
(2025-03-20)N-heterocyclic carbenes (NHCs) represent an important class of ancillary ligands for transition metal catalysis due to their strong binding character and generally simple syntheses procedures. One important feature of these ... -
Cooperative Activation of Small Molecules on Preorganized Dinuclear Cobalt Complexes
(2025-03-14)The coordination chemistry of late-transition-metal dinitrogen complexes remains a topic of considerable interest. In this study, a pyrazolate-based dinucleating nacnac ligand was employed to construct a series of bimetallic ... -
Cell-Substrate Distance Fluctuations and their Impact on Wound Healing in Epithelial Tissues
(2025-03-13)Cellular movements are fundamental to a wide array of physiological processes essential for an organism's development, maintenance, and repair. Understanding the underlying mechanisms that regulate these movements provides ... -
Investigation of Framework-forming Aggregation of Peptide Helices on Membrane Surfaces
(2025-02-14)This study presents the development and investigation of peptide-based systems designed to induce controlled aggregation on membrane surfaces, potentially facilitating cell signaling by promoting lipid raft formation. The ... -
Identification and Characterization of Intermediates in Transmetalation Reactions from Boron to Lithium and Copper
(2025-02-14)Transmetalation is a crucial elementary step in cross-coupling reactions. In this context, boron nucleophiles are especially popular and versatile, however, the fundamental details of transmetalation reactions involving ... -
Development of a Bone Adhesive Material based on Diazirinyl-Collagen Mimetic Peptides
(2025-02-05)The treatment of small and inaccessible bone fractures with metallic implants is challenging. One potential solution to this issue is the use of an adhesive to adhere the affected fragments. In the search for new biocompatible ... -
On the chemistry of sulfur: Development of NOS bridge model systems and Stereoretentive 2,3-bis(trifluoromethyl)cyclopropanation of heteroarenes via sulfonium salts
(2025-02-05)This thesis presents research conducted across two distinct projects in sulfur chemistry. The first project focused on the synthesis of model systems based on biphenyl, xanthene, and triazamacrocyclic scaffolds to investigate ... -
Enantioselective Synthesis and Postsynthetic Functionalization of Thiahelicenes and their Oxa-analogues
(2025-01-30)Based on the Alcarazo group’s experience in enantioselective Au(I)-catalyzed synthesis of (hetero)helicenes employing alkyne hydroaryration reactions, the gold precatalyst 188c, combining a chiral BINOL-derived backbone ... -
Quantitative Estimation of Cell Mechanical Cues using Elastic Micropillars
(2025-01-24)Within the intricate landscape of the cellular microenvironment, the inter- play between biochemical and physical signaling emerges as a decisive force shaping the physiology and functions of living cells. Recent insights ... -
Reductive Small Molecule Transformations with Pyrazolate-Based Bimetallic Complexes
(2025-01-23)The activation of small molecules (NO, O2, CO, CO2, N2, etc.) is important in a multitude of fields such as biology, medicine and industrial catalysis. Many synthetic catalysts were inspired by the active sites of ... -
Electron Rich Metallo Nitrene Complexes For Nitrogen Transfer
(2025-01-10)The advent of C–N bond formation by catalytic C–H amination had a huge impact on the synthesis of nitrogen-containing compounds, in academia as well as industry. In contrast to nitrogen-group transfer, complementary ... -
Development of an efficient charge equilibration method for nonlocal neural network potentials with applications in redox chemistry
(2025-01-06)This thesis focuses on the development and application of new methodologies for machine learning potentials in atomistic simulations. The primary contribution of this work is the design and implementation of an optimized ... -
Mechanistic Studies of Hydrogen Recombination and Water Formation on Palladium Surfaces
(2024-12-19)In heterogeneous catalysis, one of the major challenges is to determine which microscopic processes are of importance for the reaction to occur with desired activity and selectivity. Efforts towards a fundamental understanding ... -
Pallada-Electrocatalyzed Non-Directed C–H Alkenylation and Double C–H Arylation
(2024-12-19)The merger of electrooxidation and transition metal-catalyzed C–H activation has emerged as an increasingly viable platform in molecular syntheses that can avoid stoichiometric chemical redox agents and circuitous functional ... -
Molecularly Imprinted Polymers via RAFT Polymerisation for Biological Applications
(2024-12-03)Antibodies are of great importance in therapeutic, diagnostic and research fields. Producing antibodies synthetically has been a longstanding goal of researchers and may be achieved using molecularly imprinted polymers ... -
Evaluation of a new VUV-FEL surface science end station using atomic beam surface scattering and velocity-resolved surface reaction dynamics
(2024-12-03)Abstract: 1. Atomic oxygen scattering from HOPG It has been unequivocally established that the electronic spin of a molecule significantly influences reactivity in gas phase reactions. However, the presence of clear ... -
Proton-Coupled Electron Transfer Studies on a Series of Osmium and Iridium Hydride Complexes
(2024-11-15)Due to the important role of transition metal hydrides in organometallic catalysis, their properties and reactivity have been thoroughly investigated and reviewed. Considering their importance, substantial efforts were ... -
Manganese and Ruthenium Catalysis for Sustainable C–H Functionalizations and Polymer Synthesis
(2024-10-28)The ever-growing scarcity of resources, energy crises, and environmental pollution demand the development of sustainable chemical processes for C–C bond formations and efficient post-consumer plastic waste recycling. While ... -
3d-Metall-Käfig-Komplexe als Modelle für aktive Zentren von nicht-Häm Proteinen
(2024-10-22)This thesis presents a broad study on a new ligand system, specially designed for the mimicry of the quasi-chelating coordination by amino acid side chain residues in enzymatic pockets. The ligand system is based on an ... -
Mechanistic Studies on flat and stepped Palladium Single Crystal Surfaces: Experimental Evidence of Reaction Intermediates for the Decomposition of Formic Acid and Oxidation of Ammonia
(2024-10-04)In this work, experimental and theoretical investigations of formic acid desorption, decomposition and ammonia oxidation on single crystal palladium surfaces are presented. The formic acid system is investigated using a ...