Dokumente Fakultät für Mathematik und Informatik (inkl. GAUSS) nach Erscheinungsdatum
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A knowledge base for generating patient-specific pathways for individualized treatment decisions in clinical applications
(2022-09-29)The vast amount of published data on molecular interactions makes it increasingly challenging for researchers and practitioners to find and extract the most relevant information to target the underlying diseases. Network ... -
Neural Network Based Methods for the Conformational Landscape Determination in High Resolution Cryo-Electron Microscopy
(2022-09-22)During the last decades 3D transmission electron cryo-microscopy (cryoEM) has emerged to be the method of choice for the study of motion in larger protein complexes. The aim of Single Particle Analysis (SPA) in cryoEM is ... -
Automated Static Analysis Tools: A Multidimensional view on Software Quality Evolution
(2022-08-31)Software use is ubiquitous. The quality and the evolution of quality over long periods of time is therefore of notable importance. Software engineering research investigates software quality in multiple areas. One of ... -
Robuste ANOVA-Typ-Statistik in hochdimensionalen Mehrgruppendesigns
(2022-08-25)This thesis proves a robustness property of the ANOVA type statistic in repeated measures designs, i.e. experimental designs with multiple measurements of the same scale on the same experimental unit. As the Huynh-Feldt-test, ... -
Computational methods for random tomography with applications to cryo-EM data
(2022-08-01)Over the last decade, Cryo Electron Microscopy (cryo-EM) has emerged as a powerful and reliable technique to determine the three-dimensional (3D) structure of large macro-molecular assemblies at near atomic resolution. ... -
A Process-Oriented Framework for Security Assessment of Cyber-Physical Systems
(2022-07-28)Due to digitalization and technological advancement, systems and their requirements are changing, and there is an increasing use of Cyber-Physical Systems (CPS) with a direct connection between the physical and the digital ... -
Ausbau des Probandenmanagementsystems der Universitätsmedizin Göttingen für standortübergreifende Kooperationen in der klinischen Forschung
(2022-07-21)Clinical research is key for medical progress. Clinical trials are the most important instrument of clinical research, which are used to test efficacy and safety of new drugs and new forms of treatment on human participants. ... -
Scientific Workflow Execution Using a Dynamic Runtime Model
(2022-07-18)Research projects consist of several kinds of steps covering, e.g., individual procedures to gather data, as well as different ways to process and analyze it. Moreover, the individual steps of the project consist of a ... -
Reconstruction of Exponential Sums from Fourier Data via Rational Approximation
(2022-07-08)We develop the new ESPIRA Algorithm to reconstruct exponential sums from discrete sample values, using the discrete Fourier transform of the given sample vector. We exploit the structure of the DFT values of samples from ... -
Machine learning and statistical analysis to identify determinants of survival in primary glioblastoma using genome wide expression studies
(2022-07-05)Glioblastoma (GBM) is the most common and highly aggressive brain tumor. GBM poses unique challenges due to high rates of tumor recurrence ( 34%) and resistance to treatment. Despite advances in treatment strategies, the ... -
Contributions to the Theory of Statistical Optimal Transport
(2022-07-01)The application of optimal transport based methodologies for statistical purposes has experienced a surge of interest and activity in recent years. This doctoral thesis collects the work of four research articles on the ... -
Fast methods for metagenomic sequence search and annotation
(2022-06-16)The past two decades have seen the development of metagenomics, the study of genes and genomes of multiple organisms simultaneously. In contrast to traditional genomic techniques, which require isolating and growing ... -
Nahms Equations and Nilpotent Orbits
(2022-05-31)P. Kronheimer has identified certain space of solutions to Nahms equations with a coadjoint orbit of a nilpotent element in a complex, semi-simple Lie algebra and that way equipped the orbit with an hyperkähler structure ... -
Improving IoT device transparency by means of privacy labels
(2022-05-20)The Internet of Things (IoT) is an umbrella-term that applies to sensors, actuators and other devices that can interact with each other, or with other systems over the Internet. This technology has the potential to improve ... -
Barycenters and ANOVA for Point Pattern Data
(2022-05-10)In this thesis a new metric for point patterns is developed. A heuristic algorithm is presented, that computes barycenters with respect to the new metric. The barycenters are then used in ANOVA procedures, to assess the ... -
Secure Localization in Wireless Sensor Networks
(2022-05-10)With the growing popularity of the Internet of Things, Wireless Sensor Networks also only grow more and more common in various different forms. However, sensor data is often only useful in connection with information about ... -
On minimax detection of localized signals from indirect or correlated data
(2022-05-05)This is a cumulative thesis consisting of two papers, in which we treat two problems related to the detectability of local anomalies within certain types of data. In the first paper, we suppose that a segment of a Gaussian ... -
6D-Posenbestimmung und 3D-Objektrekonstruktion mittels der 2D-Form von Bildsegmenten
(2022-04-14)This thesis presents a template-based method for the calculation of the 6D pose with a following 3D reconstruction of objects in a scene. In applications for computer-aided manipulations, e.g., in the field of robotics, ... -
A Bioinformatics Pipeline for Identifying Dysregulated Pathways in Cancer from Comparative RNA-Seq Transcriptome Analysis
(2022-04-07)Cancer is characterized as a multifactorial disease which undergoes genetic and epige- netic changes during invasive tumor growth. Thus, numerous tumor samples have been profiled using high-throughput sequencing technologies ... -
Harmonic analysis on 2-step stratified Lie groups without the Moore-Wolf condition
(2022-04-07)In this thesis we investigate harmonic analysis on a particular class of sub-Riemannian manifold, namely the 2-step stratified Lie groups $\mathbb{G}$, as well as its applications in partial differential equations. This ...