Dokumente Fakultät für Mathematik und Informatik (inkl. GAUSS) nach Gutachter "Habeck, Michael Dr."
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A Bayesian approach to initial model inference in cryo-electron microscopy
(2016-03-18)Single-particle cryo-electron microscopy (cryo-EM) is widely used to study the structure of macromolecular assemblies. Tens of thousands of noisy two-dimensional images of the macromolecular assembly viewed from different ... -
Computational methods for random tomography with applications to cryo-EM data
(2022-08-01)Over the last decade, Cryo Electron Microscopy (cryo-EM) has emerged as a powerful and reliable technique to determine the three-dimensional (3D) structure of large macro-molecular assemblies at near atomic resolution. ... -
Multiscale Change-point Segmentation: Beyond Step Functions
(2017-03-08)Many multiscale segmentation methods have been proven to work successfully for detecting multiple change-points, mainly because they provide faithful statistical statements, while at the same time allowing for efficient ... -
Probabilistic models for protein conformational changes
(2020-06-09)Proteins are macromolecules that perform multiple functions. They are not rigid molecules, but instead proteins can change their conformation to perform critical tasks driven by binding small ligands, by assembling into ...