Dokumente Fakultät für Mathematik und Informatik (inkl. GAUSS) nach Gutachter "Waack, Stephan Prof. Dr."
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A Biased Urn Model for Taxonomic Identification
(2009-03-24)We consider a stochastic model for the problem of taxonomic identification in bacterial genomes, motivated by the detection of horizontal gene transfer between non-closely related species. ... -
A Bioinformatics Pipeline for Identifying Dysregulated Pathways in Cancer from Comparative RNA-Seq Transcriptome Analysis
(2022-04-07)Cancer is characterized as a multifactorial disease which undergoes genetic and epige- netic changes during invasive tumor growth. Thus, numerous tumor samples have been profiled using high-throughput sequencing technologies ... -
A Fine-Grain Scalable and Channel-Adaptive Hybrid Speech Coding Scheme for Voice over Wireless IP
(2006-12-13)Wireless LANs (WLANs) are being more and more widely deployed at present. They are a key element in dynamic business environments where permanent access to network resources is vital. They ... -
A Study of VoIP Performance in Anonymous Network - The Onion Routing (Tor)
(2014-06-23)Information technology is developing rapidly, especially in the field of computer science, telecommunications and information systems. In the early days of telecommunications, voice networks could not be combined with data ... -
Alignment-free Phylogeny Reconstruction Based On Quartet Trees
(2020-03-11)Traditional methods for phylogeny reconstruction are based on multiple sequence alignments and character-based methods. This combination of computationally expensive methods leads to very accurate results, but it is ... -
Alignmentfreie Analyse von Proteinsequenzen mit Verfahren des maschinellen Lernens
(2008-10-08)Currently, alignment-based methods are routinely used for functional characterization of novel protein sequences. However, these methods are computationally demanding for large sequence ... -
Analysis of expression profile and gene variation via development of methods for Next Generation Sequencing data
(2018-11-27)Since the last ten to twenty years, the cost of sequencing the human genome decreased continuously. Therefore the interest in RNA sequencing (RNA-Seq) rose as it can be used to discover the molecular mechanisms behind ... -
Application of A Novel Triclustering Method in Analyzing Three Dimensional Transcriptomics Data
(2015-06-19)Due to the advancement of microarray technology over the last decade, it is feasible to monitor the gene expression dynamics not only over a set of replicates but also either a set of time points or doses of chemical ... -
Classifiers for Discrimination of Significant Protein Residues and Protein-Protein Interaction Using Concepts of Information Theory and Machine Learning
(2012-01-18)The field of protein-analysis is a major research area for bioinformatics. Especially the field of predicting important sites in proteins is in the focus of research to reduce the cost and ... -
Constructing Temporal Transcriptional Regulatory Cascades in the Context of Development and Cell Differentiation
(2020-07-14)Cell differentiation is a complex process orchestrated by sets of regulators appearing at precise temporal points, resulting in regulatory cascades that affect the expression of broader sets of genes, ending up in the ... -
Deep Learning Metadata Fusion for Traffic Light to Lane Assignment
(2019-08-01)This dissertation focuses on a novel deep fusion method with heterogeneous metadata and image data to resolve the one-to-many traffic light to lane assignment problem. The traffic light to lane assignment belongs to the ... -
Detektion und Analyse synergistischer Einflüsse multipler Stimuli auf zelluläre Signaltransduktionsnetzwerke in Säugetieren
(2013-11-21)Simultaneously working signals affect the behavior of organisms at systems level. Different signals have to be integrated and evaluated simultaneously by the cell. Synergistic interactions are one possibility how a cell ... -
Developer-Centric Software Assessment
(2018-06-14)Software systems are becoming more and more widespread in all areas of everyday life. Due to the increasing reliance on such systems, there is a need to keep them operational over longer periods of time under constantly ... -
Development and application of ontologies for biological applications
(2016-02-08)In the century of information technology automatic processing of knowledge is evolving to be a crucial challenge. However, it is usually not obvious to extract information from the syntax of texts. Hence, ontologies are ... -
Development and evaluation of a conceptual model with an electronic medical record system for diabetes management in Sub-Saharan Africa
(2011-04-08)Diabetes mellitus is today the cause of an important and expensive health crisis in Sub-Saharan Africa (SSA). Scientific publications and research reports of the World Health Organization ... -
Development of Agent-Based Simulation Models for Software Evolution
(2020-02-11)Software has become a part of everyday life for us. This is also associated with increasing requirements for adaptability to rapidly changing environments. This evolutionary process of software is being studied by a software ... -
Development of algorithms and next-generation sequencing data workflows for the analysis of gene regulatory networks
(2017-04-11)Unraveling genetic and epigenetic mechanisms behind various biological processes is possible with Next generation sequencing (NGS) methodologies, with a multitude of tools developed to analyze such data. Nevertheless, ... -
Development of novel Classical and Quantum Information Theory Based Methods for the Detection of Compensatory Mutations in MSAs
(2014-05-13)Multiple sequence alignments (MSAs) of homologous proteins are useful tools to characterize compensatory mutations between non-conserved residue sites. The identification of these residue sites in MSAs is an important ... -
Evaluierung des phylogenetischen Footprintings und dessen Anwendung zur verbesserten Vorhersage von Transkriptionsfaktor-Bindestellen
(2006-10-27)The human genome contains between 20000 and 25000 genes, which code for proteins, and RNA genes of different function, but approximately 95% of the human genome are presumably not transcribed. ... -
Fast methods for metagenomic sequence search and annotation
(2022-06-16)The past two decades have seen the development of metagenomics, the study of genes and genomes of multiple organisms simultaneously. In contrast to traditional genomic techniques, which require isolating and growing ...